Management of symptomatic, asymptomatic, and recurrent hiatal hernia: a systematic review and meta-analysis.

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Surgical endoscopy


Hernia, Hiatal; Humans; Recurrence; Fundoplication; Herniorrhaphy; Surgical Mesh; Asymptomatic Diseases; Reoperation; Fundoplication; Hernia; Hiatal; Mesh; Meta-analysis; Systematic review; oregon; portland; ppmc


BACKGROUND: The surgical management of hiatal hernia remains controversial. We aimed to compare outcomes of mesh versus no mesh and fundoplication versus no fundoplication in symptomatic patients; surgery versus observation in asymptomatic patients; and redo hernia repair versus conversion to Roux-en-Y reconstruction in recurrent hiatal hernia.

METHODS: We searched PubMed, Embase, CINAHL, Cochrane Library and the databases between 2000 and 2022 for randomized controlled trials (RCTs), observational studies, and case series (asymptomatic and recurrent hernias). Screening was performed by two trained independent reviewers. Pooled analyses were performed on comparative data. Risk of bias was assessed using the Cochrane Risk of Bias tool and Newcastle Ottawa Scale for randomized and non-randomized studies, respectively.

RESULTS: We included 45 studies from 5152 retrieved records. Only six RCTs had low risk of bias. Mesh was associated with a lower recurrence risk (RR = 0.50, 95%CI 0.28, 0.88; I

CONCLUSIONS: The evidence for optimal management of symptomatic and recurrent hiatal hernia remains controversial, underpinned by studies with a high risk of bias. Shared decision making between surgeon and patient is essential for optimal outcomes.

Clinical Institute

Digestive Health