Title

Granuloma-like lesion at subcutaneous immunoglobulin site in a common variable immunodeficiency patient.

Authors

Ankmalika Gupta, Department of Medicine, Hoag Medical Group, Newport Beach, CA 92697, USA.
Beverly Wang
Sudhir Gupta

Document Type

Article

Publication Date

10-1-2019

Publication Title

Immunotherapy

Keywords

Common Variable Immunodeficiency; Granuloma; Humans; Immunization, Passive; Immunoglobulins, Intravenous; Injections, Subcutaneous; Middle Aged

Abstract

Immunoglobulin therapy is the main stay in the treatment of primary antibody deficiencies. Granulomatous lesions are common complication in patients with common variable immunodeficiency (CVID). We present the first case of cutaneous granuloma-like lesion at site of subcutaneous immunoglobulin injections in a patient with CVID. These lesions resolve overtime following switching treatment to intravenous immunoglobulin. Unlike granulomas associated with CVID, granulomatous lesion in this patient did not require any specific therapy, and resolved over a period of 4 weeks following switching subcutaneous immunoglobulin to intravenous immunoglobulin.

Department

Pathology & Laboratory Medicine

Recommended Citation

Gupta, Ankmalika; Wang, Beverly; and Gupta, Sudhir, "Granuloma-like lesion at subcutaneous immunoglobulin site in a common variable immunodeficiency patient." (2019). Articles, Abstracts, and Reports. 3211.
https://digitalcommons.providence.org/publications/3211