Sulfur Metabolites Play Key System-Level Roles in Modulating Denitrification.
washington; seattle; isb
Competition between nitrate-reducing bacteria (NRB) and sulfate-reducing bacteria (SRB) for resources in anoxic environments is generally thought to be governed largely by thermodynamics. It is now recognized that intermediates of nitrogen and sulfur cycling (e.g., hydrogen sulfide, nitrite, etc.) can also directly impact NRB and SRB activities in freshwater, wastewater, and sediment and therefore may play important roles in competitive interactions. Here, through comparative transcriptomic and metabolomic analyses, we have uncovered mechanisms of hydrogen sulfide- and cysteine-mediated inhibition of nitrate respiratory growth for the NRB
Institute for Systems Biology
Otwell, Anne E; Carr, Alex V; Majumder, Erica L W; Ruiz, Maryann K; Wilpiszeski, Regina L; Hoang, Linh T; Webb, Bill; Turkarslan, Serdar; Gibbons, Sean M; Elias, Dwayne A; Stahl, David A; Siuzdak, Gary; and Baliga, Nitin S, "Sulfur Metabolites Play Key System-Level Roles in Modulating Denitrification." (2021). Articles, Abstracts, and Reports. 4460.