Effects of a topical botanically-enriched salve on cutaneous oxygenation.
Journal of wound care
Administration, Cutaneous; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Foot; Double-Blind Method; Female; Humans; Male; Middle Aged; Ointments; Oxygen; Plant Extracts; Skin; Treatment Outcome; Wound Healing
OBJECTIVE: There is a medical need to evaluate new treatments that may improve wound healing. This study aimed to determine if Original Healing Salve (OHS, Puremedy, Inc.) a topical, botanically-enriched salve (BES), changes distal leg tissue oxygenation in people with type 2 diabetes.
METHOD: A randomised, controlled, crossover, double-blinded clinical trial comparing changes in cutaneous oxygen delivery (mean TcPO
RESULTS: A total of 16 participants were recruited. Analysis of the primary outcome demonstrated no statistically significant difference in TcPO
CONCLUSION: These findings support consideration of topical treatments containing botanical ingredients to increase cutaneous oxygen delivery in the lower extremity in patients with type 2 diabetes.
Kidney & Diabetes
Corroon, Jamie; Bradley, Ryan; Erlandsen, Andrew; Taylor, Jan; and Hanes, Doug, "Effects of a topical botanically-enriched salve on cutaneous oxygenation." (2019). Articles, Abstracts, and Reports. 5309.