Publication Title

Epilepsy Behav Case Rep

Document Type

Article

Publication Date

1-1-2018

Keywords

Circadian; Glucose; Hypometabolism; Insulin; Nonketotic; Stimulation

Abstract

Objectives: To investigate if glucose levels influence seizure patterns.

Materials and methods: In a patient with RNS/NeuroPace implanted bi-temporally and type 1 diabetes mellitus, seizure event times and onset locations were matched to continuous tissue glucose.

Results: Left focal seizure (LFS, n = 22) glucoses averaged 169 mg/dL, while right focal seizure (RFS, n = 23) glucoses averaged 131 mg/dL (p = 0.03). LFS occurred at mean time 17:02 while RFS occurred at 04:23. LFS spread to the contralateral side (n = 19) more than RFS (n = 2).

Conclusion: Seizure onset laterality and spread vary with glucose and time of seizure.

Clinical Institute

Neurosciences (Brain & Spine)

Specialty

Neurosciences

Included in

Neurology Commons

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