Epilepsy Behav Case Rep
Circadian; Glucose; Hypometabolism; Insulin; Nonketotic; Stimulation
Objectives: To investigate if glucose levels influence seizure patterns.
Materials and methods: In a patient with RNS/NeuroPace implanted bi-temporally and type 1 diabetes mellitus, seizure event times and onset locations were matched to continuous tissue glucose.
Results: Left focal seizure (LFS, n = 22) glucoses averaged 169 mg/dL, while right focal seizure (RFS, n = 23) glucoses averaged 131 mg/dL (p = 0.03). LFS occurred at mean time 17:02 while RFS occurred at 04:23. LFS spread to the contralateral side (n = 19) more than RFS (n = 2).
Conclusion: Seizure onset laterality and spread vary with glucose and time of seizure.
Neurosciences (Brain & Spine)
Kinnear, Katie M; Warner, Nicole M; Haltiner, Alan M; and Doherty, Michael J, "Continuous monitoring devices and seizure patterns by glucose, time and lateralized seizure onset." (2018). Articles, Abstracts, and Reports. 611.