Title
Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research.
Document Type
Article
Publication Date
8-19-2022
Publication Title
iScience
Keywords
washington; isb; seattle
Abstract
The extracellular RNA communication consortium (ERCC) is an NIH-funded program aiming to promote the development of new technologies, resources, and knowledge about exRNAs and their carriers. After Phase 1 (2013-2018), Phase 2 of the program (ERCC2, 2019-2023) aims to fill critical gaps in knowledge and technology to enable rigorous and reproducible methods for separation and characterization of both bulk populations of exRNA carriers and single EVs. ERCC2 investigators are also developing new bioinformatic pipelines to promote data integration through the exRNA atlas database. ERCC2 has established several Working Groups (Resource Sharing, Reagent Development, Data Analysis and Coordination, Technology Development, nomenclature, and Scientific Outreach) to promote collaboration between ERCC2 members and the broader scientific community. We expect that ERCC2's current and future achievements will significantly improve our understanding of exRNA biology and the development of accurate and efficient exRNA-based diagnostic, prognostic, and theranostic biomarker assays.
Department
Institute for Systems Biology
Recommended Citation
Mateescu, Bogdan; Jones, Jennifer C; Alexander, Roger P; Alsop, Eric; An, Ji Yeong; Asghari, Mohammad; Boomgarden, Alex; Bouchareychas, Laura; Cayota, Alfonso; Chang, Hsueh-Chia; Charest, Al; Chiu, Daniel T; Coffey, Robert J; Das, Saumya; De Hoff, Peter; deMello, Andrew; D'Souza-Schorey, Crislyn; Elashoff, David; Eliato, Kiarash R; Franklin, Jeffrey L; Galas, David J; Gerstein, Mark B; Ghiran, Ionita H; Go, David B; Gould, Stephen; Grogan, Tristan R; Higginbotham, James N; Hladik, Florian; Huang, Tony Jun; Huo, Xiaoye; Hutchins, Elizabeth; Jeppesen, Dennis K; Jovanovic-Talisman, Tijana; Kim, Betty Y S; Kim, Sung; Kim, Kyoung-Mee; Kim, Yong; Kitchen, Robert R; Knouse, Vaughan; LaPlante, Emily L; Lebrilla, Carlito B; Lee, L James; Lennon, Kathleen M; Li, Guoping; Li, Feng; Li, Tieyi; Liu, Tao; Liu, Zirui; Maddox, Adam L; McCarthy, Kyle; Meechoovet, Bessie; Maniya, Nalin; Meng, Yingchao; Milosavljevic, Aleksandar; Min, Byoung-Hoon; Morey, Amber; Ng, Martin; Nolan, John; De Oliveira Junior, Getulio P; Paulaitis, Michael E; Phu, Tuan Anh; Raffai, Robert L; Reátegui, Eduardo; Roth, Matthew E; Routenberg, David A; Rozowsky, Joel; Rufo, Joseph; Senapati, Satyajyoti; Shachar, Sigal; Sharma, Himani; Sood, Anil K; Stavrakis, Stavros; Stürchler, Alessandra; Tewari, Muneesh; Tosar, Juan P; Tucker-Schwartz, Alexander K; Turchinovich, Andrey; Valkov, Nedyalka; Van Keuren-Jensen, Kendall; Vickers, Kasey C; Vojtech, Lucia; Vreeland, Wyatt N; Wang, Ceming; Wang, Kai; Wang, ZeYu; Welsh, Joshua A; Witwer, Kenneth W; Wong, David T W; Xia, Jianping; Xie, Ya-Hong; Yang, Kaichun; Zaborowski, Mikołaj P; Zhang, Chenguang; Zhang, Qin; Zivkovic, Angela M; and Laurent, Louise C, "Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research." (2022). Articles, Abstracts, and Reports. 6443.
https://digitalcommons.providence.org/publications/6443
