Title

Glioblastoma: Biology, Diagnosis, and Treatment

Authors

Akanksha Sharma, Department of Translational Neurosciences, Pacific Neuroscience Institute at Saint John Cancer Institute, Santa Monica, CA, USAFollow
Maciej M. Mrugala
Jan Buckner

Document Type

Book

Publication Date

2019

Publication Title

Encyclopedia of Cancer (Third Edition)

Keywords

california; sjci

Abstract

Glioblastoma accounts for the majority of malignant primary brain tumors and is an aggressive cancer with high morbidity and mortality. Despite surgical resection, radiation and chemotherapy, survival can still be as little as 15 months. This article aims to provide a concise summary of this cancer, discussing its history, epidemiology, etiology and classification, its clinical presentation and diagnosis, and current treatment modalities as well as their rationale. There continue to be significant advances that hold great promise for treatments for this tumor, and we discuss several key developments that are on the horizon.

Clinical Institute

Neurosciences (Brain & Spine)

Clinical Institute

Cancer

Department

Neurosciences

Department

Oncology

Recommended Citation

Sharma, Akanksha; Mrugala, Maciej M.; and Buckner, Jan, "Glioblastoma: Biology, Diagnosis, and Treatment" (2019). Articles, Abstracts, and Reports. 7435.
https://digitalcommons.providence.org/publications/7435