International consensus statement on allergy and rhinology: Sinonasal tumors.


Edward C Kuan
Eric W Wang
Nithin D Adappa
Daniel M Beswick
Nyall R London
Shirley Y Su
Marilene B Wang
Waleed M Abuzeid
Borislav Alexiev
Jeremiah A Alt
Paolo Antognoni
Michelle Alonso-Basanta
Pete S Batra
Mihir Bhayani
Diana Bell
Manuel Bernal-Sprekelsen
Christian S Betz
Jean-Yves Blay
Benjamin S Bleier
Juliana Bonilla-Velez
Claudio Callejas
Ricardo L Carrau
Roy R Casiano
Paolo Castelnuovo
Rakesh K Chandra
Vasileios Chatzinakis
Simon B Chen
Alexander G Chiu
Garret Choby
Naweed I Chowdhury
Martin J Citardi
Marc A Cohen
Roi Dagan
Gianluca Dalfino
Iacopo Dallan
Camila Soares Dassi
John de Almeida
Angelo P Dei Tos
John M DelGaudio
Charles S Ebert
Ivan H El-Sayed
Jean Anderson Eloy
James J Evans
Christina H Fang
Nyssa F Farrell
Marco Ferrari
Nancy Fischbein
Adam Folbe
Wytske J Fokkens
Meha G Fox
Valerie J Lund
Gary L Gallia
Paul A Gardner
Mathew Geltzeiler
Christos Georgalas
Anne E Getz
Satish Govindaraj
Stacey T Gray
Jessica W Grayson
Bradley A Gross
Jordon G Grube
Ruifeng Guo
Patrick K Ha
Ashleigh A Halderman
Ehab Y Hanna
Richard J Harvey
Stephen C Hernandez
Adam L Holtzman
Claire Hopkins
Zhigang Huang
Zhenxiao Huang
Ian M Humphreys
Peter H Hwang
Alfred M Iloreta
Masaru Ishii
Michael E Ivan
Aria Jafari
David W Kennedy
Mohemmed Khan
Adam J Kimple
Todd T Kingdom
Anna Knisely, Department of Skull Base and Minimally Invasive Neurosurgery, Swedish Neuroscience Institute, Seattle, Washington, United States.Follow
Ying-Ju Kuo
Devyani Lal
Eric D Lamarre
Ming-Ying Lan
Hien Le
Matt Lechner
Nancy Y Lee
Jivianne K Lee
Victor H Lee
Corinna G Levine
Jin-Ching Lin
Derrick T Lin
Brian C Lobo
Tran Locke
Amber U Luong
Kelly R Magliocca
Svetomir N Markovic
Gesa Matnjani
Erin L McKean
Cem Meço
William M Mendenhall
Loren Michel
Shorook Na'ara
Piero Nicolai
Daniel W Nuss
Gurston G Nyquist
Gretchen M Oakley
Kazuhiro Omura
Richard R Orlandi
Nobuyoshi Otori
Peter Papagiannopoulos
Zara M Patel
David G Pfister
Jack Phan
Alkis J Psaltis
Mindy R Rabinowitz
Murugappan Ramanathan
Ryan Rimmer
Marc R Rosen
Olabisi Sanusi
Zoukaa B Sargi
Philippe Schafhausen
Rodney J Schlosser
Ahmad R Sedaghat
Brent A Senior
Raj Shrivastava
Raj Sindwani
Timothy L Smith
Kristine A Smith
Carl H Snyderman
C Arturo Solares
Satyan B Sreenath
Aldo Stamm
Katharina Stölzel
Baran Sumer
Pavol Surda
Bobby A Tajudeen
Lester D R Thompson
Brian D Thorp
Charles C L Tong
Raymond K Tsang
Justin H Turner
Mario Turri-Zanoni
Aaron M Udager
Thibaut van Zele
Kyle VanKoevering
Kevin C Welch
Sarah K Wise
Ian J Witterick
Tae-Bin Won
Stephanie N Wong
Bradford A Woodworth
Peter-John Wormald
William C Yao
Chien-Fu Yeh
Bing Zhou
James N Palmer

Document Type


Publication Date


Publication Title

Int Forum Allergy Rhinol


washington; swedish; adenocarcinoma; adenoid cystic carcinoma; adjuvant therapy; angiofibroma; biopsy; chemotherapy; concurrent; endoscopic endonasal approach; esthesioneuroblastoma; evidence-based medicine; head and neck cancer; head and neck oncology; immunotherapy; induction chemotherapy; inverted papilloma; lymphoma; margins; metastases; mucosal melanoma; nasopharyngeal carcinoma; neoadjuvant therapy; neuroectodermal carcinoma; neuroendocrine carcinoma; olfactory neuroblastoma; open approach; orbit; papilloma; quality of life; radiation; resectability; rhabdomyosarcoma; risk factors; sarcoma; sinonasal cancer; sinonasal malignancy; sinonasal neoplasm; sinonasal oncology; sinonasal papilloma; sinonasal tumor; sinonasal undifferentiated carcinoma; skull base; squamous cell carcinoma; surgery; surveillance; survival; survivorship


BACKGROUND: Sinonasal neoplasms, whether benign and malignant, pose a significant challenge to clinicians and represents a model area for multidisciplinary collaboration in order to optimize patient care. The International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors (ICSNT) aims to summarize the best available evidence and presents 48 thematic and histopathology-based topics spanning the field.

METHODS: In accordance with prior ICAR documents, ICSNT assigned each topic as an Evidence-Based Review with Recommendations, Evidence-Based Review, and Literature Review based on level of evidence. An international group of multidisciplinary author teams were assembled for the topic reviews using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses format, and completed sections underwent a thorough and iterative consensus-building process. The final document underwent rigorous synthesis and review prior to publication.

RESULTS: The ICNST document consists of 4 major sections: general principles, benign neoplasms and lesions, malignant neoplasms, and quality of life and surveillance. It covers 48 conceptual and/or histopathology-based topics relevant to sinonasal neoplasms and masses. Topics with a high level of evidence provided specific recommendations, while other areas summarized the current state of evidence. A final section highlights research opportunities and future directions, contributing to advancing knowledge and community intervention.

CONCLUSION: As an embodiment of the multidisciplinary and collaborative model of care in sinonasal neoplasms and masses, ICSNT was designed as a comprehensive, international, and multidisciplinary collaborative endeavor. Its primary objective is to summarize the existing evidence in the field of sinonasal neoplasms and masses. This article is protected by copyright. All rights reserved.

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