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Maternal, Child Health and Neonatal Nursing | Nursing


Objective: The aim of this IRB approved study was to evaluate the impact of ibuprofen on Mean Arterial Pressure (MAP) in the immediate postpartum period of women with preeclampsia.

Design: A retrospective chart audit of 633 preeclampsia patients who had treated severe hypertension (BP > 160/105) during their hospital stay.

Setting: Metropolitan Level 3 facility in Portland OR.

Patients/Participants: 169 patients met criteria; received magnesium sulfate postpartum and had severe hypertension postpartum. 60 were randomly selected, 30 received ibuprofen, 30 did not.

Methods: Baseline was obtained at 2 hours postpartum. Each patients MAP for each 24 hour interval were averaged. The Mean arterial pressures (MAP) were compared in women who received Ibuprofen versus those who did not. MAPs of the two groups of patients were then compared at the following intervals: 24, 48, 72 and 96 hours and compared using t-tests to determine statistical significance.

Results: When comparing the average overall MAP pressures between the two groups of patients, there was no significant difference. In other words there was no statistically significant difference in average blood pressure at the following time intervals: 2 to 24 (p=0.46), 24 to 48 (p=0.56), 48 to 72 (p=0.45), 72 to 96 (p=0.49) Average total hours (p=0.48)

Implications for nursing practice: Our data collection results revealed that there was not a significant increase in MAP for Preeclamptic patients who received Ibuprofen in the postpartum period which is consistent with the current literature. Based on this finding, Ibuprofen following birth should be included in the pain control plan in hopes to reduce narcotic use and dependence

Clinical Institute

Women & Children




Obstetrics & Gynecology

Conference / Event Name

Association of Women’s Health, Obstetric and Neonatal Nurses Convention


Atlanta, GA, United States


Updated version of the poster found here:

Ibuprofen Does Not Increase Blood Pressure in Preeclampsia