A large-scale database of T-cell receptor beta sequences and binding associations from natural and synthetic exposure to SARS-CoV-2.
Publication Title
Front Immunol
Document Type
Article
Publication Date
1-1-2025
Keywords
washington; isb; swedish; covid-19
Abstract
We describe the establishment and current content of the ImmuneCODE™ database, which includes hundreds of millions of T-cell Receptor (TCR) sequences from over 1,400 subjects exposed to or infected with the SARS-CoV-2 virus, as well as over 160,000 high-confidence SARS-CoV-2-associated TCRs. This database is made freely available, and the data contained in it can be used to assist with global efforts to understand the immune response to the SARS-CoV-2 virus and develop new interventions.
Specialty/Research Institute
Infectious Diseases
Specialty/Research Institute
Institute for Systems Biology
DOI
10.3389/fimmu.2025.1488851
COinS
