Pharmacologic Strategies for Exercise-Induced Bronchospasm with a Focus on Athletes.
Publication Title
Immunology and allergy clinics of North America
Document Type
Article
Publication Date
5-1-2018
Keywords
Adrenergic beta-Agonists; Asthma, Exercise-Induced; Athletes; Doping in Sports; Exercise; Humans; Performance-Enhancing Substances; Respiratory System; Asthma; Doping; EIB; Exercise; Treatment
Abstract
Exercise-induced bronchoconstriction (EIB) is the transient narrowing of the airways during and after exercise that occurs in response to increased ventilation in susceptible individuals. It occurs across the age spectrum in patients with underlying asthma and can occur in athletes without baseline asthma. The inflammatory mechanisms underlying EIB in patients without asthma may be distinct from those underlying EIB in patients with asthma. This review summarizes mechanistic and clinical data that can guide the choice of chronic and acute pharmacologic therapies targeting control of EIB. Relevant regulations from the World Anti-Doping Agency are also discussed.
Clinical Institute
Orthopedics & Sports Medicine
Specialty/Research Institute
Sports Medicine
Specialty/Research Institute
Pulmonary Medicine
