Updates in Management of Locally and Regionally Advanced Basal Cell Carcinoma.
Publication Title
The Surgical clinics of North America
Document Type
Article
Publication Date
6-1-2025
Keywords
california; santa monica; sjci
Abstract
Basal cell carcinoma (BCC) is a slow-growing skin cancer that tends to remain localized but that can occasionally grow extensively and penetrate deeper tissues (locally advanced BCC [laBCC]). The first line of treatment for laBCC is surgical excision, but when resection is not possible systemic therapies such as Hedgehog pathway inhibitors or immune checkpoint inhibitors are indicated. The management of laBCC relies on a multidisciplinary team approach; the goals of treatment include local control, palliation of symptoms, achieving acceptable cosmetic results, and reduce the risk of recurrence.
Area of Special Interest
Cancer
Specialty/Research Institute
Dermatology
Specialty/Research Institute
Oncology
Specialty/Research Institute
Surgery
DOI
10.1016/j.suc.2024.11.012