Updates in Management of Locally and Regionally Advanced Basal Cell Carcinoma.

Publication Title

The Surgical clinics of North America

Document Type

Article

Publication Date

6-1-2025

Keywords

california; santa monica; sjci

Abstract

Basal cell carcinoma (BCC) is a slow-growing skin cancer that tends to remain localized but that can occasionally grow extensively and penetrate deeper tissues (locally advanced BCC [laBCC]). The first line of treatment for laBCC is surgical excision, but when resection is not possible systemic therapies such as Hedgehog pathway inhibitors or immune checkpoint inhibitors are indicated. The management of laBCC relies on a multidisciplinary team approach; the goals of treatment include local control, palliation of symptoms, achieving acceptable cosmetic results, and reduce the risk of recurrence.

Area of Special Interest

Cancer

Specialty/Research Institute

Dermatology

Specialty/Research Institute

Oncology

Specialty/Research Institute

Surgery

DOI

10.1016/j.suc.2024.11.012

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