Cervical Sagittal Alignment Revisited on the Path to Personalized Spine Surgery: A Big Picture Perspective Through Bibliometric Analysis and Visualization.

Publication Title

World Neurosurg

Authors

Luke L Jouppi, Seattle Science Foundation, Seattle, Washington, USA; Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USA. Electronic address: luke.l.jouppi@gmail.com.Follow
Clifford A Pierre, Seattle Science Foundation, Seattle, Washington, USA; Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USA.Follow
Anna Gorbacheva
Julius Gerstmeyer, Seattle Science Foundation, Seattle, Washington, USA; Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USA; Department of General and Trauma Surgery, BG University Hospital Bergmannsheil, Ruhr University Bochum, Bochum, Germany.Follow
Colin Gold, Seattle Science Foundation, Seattle, Washington, USA; Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USA.Follow
Cameron Hogsett, Seattle Science Foundation, Seattle, Washington, USA; Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USA.Follow
Nick Minissale, Seattle Science Foundation, Seattle, Washington, USA; Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USA.Follow
Mark Kraemer, Seattle Science Foundation, Seattle, Washington, USA; Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USA.Follow
Stephen Lockey
Amir Abdul-Jabbar, Seattle Science Foundation, Seattle, Washington, USA; Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USA.Follow
Rod J Oskouian, Seattle Science Foundation, Seattle, Washington, USA; Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USA.Follow
Jens R Chapman, Seattle Science Foundation, Seattle, Washington, USA; Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USA.Follow

Document Type

Article

Publication Date

10-1-2025

Keywords

Humans; Bibliometrics; Cervical Vertebrae; Precision Medicine; Alignment target; Cervical sagittal alignment; Cobb angle; Deformity; Kyphosis; Personalized medicine; Sagittal; Sagittal vertical axis; T1 slope.; washington; swedish; swedish neurosciences

Abstract

OBJECTIVE: Spinal alignment has become a focal point of spine deformity surgery amid an increased emphasis on global balance. Following a strong focus on thoracolumbar alignment, the cervical spine has recently emerged as a key area for further investigations. We applied formal bibliographic analytic techniques to assess trends regarding cervical sagittal alignment over time.

METHODS: Data was collected from the Clarivate Web of Science, PubMed, and Scopus databases on 08/02/2025 utilizing the keyword search ("cervical" OR "cervical spine") AND ("sagittal imbalance" OR "sagittal balance" OR "sagittal alignment" OR "sagittal malalignment"). Excel was used to create the publication years, citations per year, publishing journals, countries, author figures. VosViewer was used to create the network visualizations of keyword co-occurrence, cocitation, country copublication, and coauthorship analyses.

RESULTS: We identified an over ten-fold increase every fifteen years in cervical sagittal alignment-related publications, starting with one study published in 1994 rising to 161 published in 2023. This trend outpaces global increases in spine publications by over sixfold. Notable jumps occurred from both 2012-2013 and 2016-2017, with over 50% increases in publications year over year. In the last five years, there has been an increasing focus on deformity, laminectomy, and motion.

CONCLUSIONS: Cervical sagittal alignment has received a rapid and disproportionate increase in publications in the last ten years which may reflect increased interest in personalized surgery through deformity correction and motion preservation. Our study provides a graphic perspective on this topic and reflects the importance of spinal alignment in all sections of the spinal column.

Area of Special Interest

Neurosciences (Brain & Spine)

Area of Special Interest

Orthopedics & Sports Medicine

Specialty/Research Institute

Neurosciences

Specialty/Research Institute

Orthopedics

DOI

10.1016/j.wneu.2025.124387

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