Effects of Obesity on Warfarin Reversal With Vitamin K.
Publication Title
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Document Type
Article
Publication Date
1-1-2019
Keywords
anticoagulants; bleeding; clinical pharmacology
Abstract
Phytonadione (vitamin K1, VK) is fat soluble and may be sequestered by adipose tissue, thus potentially altering drug distribution in obese patients requiring warfarin reversal. This single-center retrospective cohort study aimed to determine the effects of obesity (defined as body mass index [BMI] ≥ 30 kg/m
Specialty/Research Institute
Pharmacy
Specialty/Research Institute
Nutrition
COinS
