Effects of Obesity on Warfarin Reversal With Vitamin K.

Publication Title

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

Document Type

Article

Publication Date

1-1-2019

Keywords

anticoagulants; bleeding; clinical pharmacology

Abstract

Phytonadione (vitamin K1, VK) is fat soluble and may be sequestered by adipose tissue, thus potentially altering drug distribution in obese patients requiring warfarin reversal. This single-center retrospective cohort study aimed to determine the effects of obesity (defined as body mass index [BMI] ≥ 30 kg/m

Specialty

Pharmacy

Specialty

Nutrition

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