Commonly integrated epigenetic modifications of differentially expressed genes lead to adaptive resistance in cancer.

Publication Title

Epigenomics

Authors

Abdullah Al Emran
Diego M Marzese, Department of Translational Molecular Medicine, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CAFollow
Dinoop R Menon, Department of Translational Molecular Medicine, John Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA
Heinz Hammerlindl
Farzana Ahmed
Erika Richtig
Pascal Duijf
Dave S B Hoon, Department of Translational Molecular Medicine, John Wayne Cancer Institute (JWCI), Pacific Neuroscience Institute, Saint John's Health Center, Providence Health Systems, Santa Monica, CA, 90404, USAFollow
Helmut Schaider

Document Type

Article

Publication Date

5-1-2019

Keywords

DNA methylation; IDTC; LINE-1; adaptive resistance; differentially expressed genes; epigenetic remodeling; induced drug-tolerant cell; repressive histone marks; viral mimicry

Clinical Institute

Cancer

Specialty/Research Institute

Oncology