Robotic partial nephrectomy versus radical nephrectomy in elderly patients with large renal masses.

Publication Title

Minerva urologica e nefrologica = The Italian journal of urology and nephrology

Document Type

Article

Publication Date

9-13-2019

Abstract

BACKGROUND: Recent evidence suggests that the "oldest old" patients might benefit of partial nephrectomy (PN), but decisionmaking for this subset of patients is still controversial. Aim of this study is to compare outcomes of robotic partial (RPN) or radical nephrectomy (RRN) for large renal masses in patients older than 65 years.

METHODS: We identified 417 ≥65 years old patients who underwent robotic radical nephrectomy (RRN) or RPN for cT1b or ≥cT2 renal mass at 17 high volume centers. Propensity score match analysis was performed adjusting for age, ASA≥3, pre-operative eGFR, and clinical tumor size. Predictors of complications, functional and oncological outcomes were evaluated in multivariable logistic and Cox regression models.

RESULTS: After propensity score analysis, 73 patients in the RPN group were matched with 74 in the RRN group. R.E.N.A.L. Score (9.6±1.7 vs 8.6±1.7; p

CONCLUSIONS: RPN In elderly patientswith large renal masses provides RPN offers acceptable surgical, and oncological outcomes allowing better functional preservation relative to RRN. The decision to undergo RPN in this subset of patients should be tailored on a case by case basis.

Clinical Institute

Kidney & Diabetes

Specialty/Research Institute

Nephrology

Specialty/Research Institute

Geriatrics

Specialty/Research Institute

Urology

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