Current perspectives into the evaluation and management of hepatitis B: a review.

Publication Title

Hepatobiliary Surg Nutr

Authors

Vignan Manne, Liver Care Network and Organ Care Research, Swedish Medical Center, 1124 Columbia Street, Suite 600, Seattle, WA, 98104, USAFollow
Eric Gochanour, Liver Care Network, Swedish Medical Center, Seattle, WA, USAFollow
Kris V Kowdley, Liver Care Network and Organ Care Research, Swedish Medical Center, 1124 Columbia Street, Suite 600, Seattle, WA, 98104, USAFollow

Document Type

Article

Publication Date

8-1-2019

Abstract

Hepatitis B is a widespread disease which affects millions of people worldwide. Chronic hepatitis B (CHB) can lead to significant morbidity and mortality due to complications such as cirrhosis and hepatocellular carcinoma. The pathophysiology of hepatitis is critical to diagnosing CHB. Deciding which patients with CHB should be treated is an important decision as treatment can often lead to better outcomes in the appropriate patient population. The nucleos(t)ide analog inhibitors entecavir and tenofovir are currently the mainstay of treatment as they are able to successfully suppress the virus and lead to fewer complications. Novel therapies are currently being developed which may offer a potential cure for this disease in the future.

Clinical Institute

Digestive Health

Specialty/Research Institute

Hepatology