Identification of the Causes for Chronic Hypokalemia: Importance of Urinary Sodium and Chloride Excretion.
Publication Title
The American journal of medicine
Document Type
Article
Publication Date
7-1-2017
Keywords
Acidosis, Renal Tubular; Adult; Anorexia Nervosa; Bartter Syndrome; Body Mass Index; Bulimia; Chlorides; Chronic Disease; Diuretics; Female; Gitelman Syndrome; Humans; Hypokalemia; Laxatives; Male; Prospective Studies; Sex Factors; Sodium; Substance-Related Disorders
Abstract
BACKGROUND: Uncovering the correct diagnosis of chronic hypokalemia with potassium (K
METHODS: Normotensive patients referred to our tertiary academic medical center for the evaluation of chronic hypokalemia were prospectively enrolled over 5 years. Clinical features, laboratory examinations-including blood and spot urine electrolytes, acid-base status, biochemistries, and hormones-as well as genetic analysis, were determined.
RESULTS: Ninety-nine patients with chronic normotensive hypokalemia (serum K
CONCLUSION: Besides body mass index, sex, and blood acid-base status, integrated interpretation of the urine Na
Clinical Institute
Kidney & Diabetes
Specialty/Research Institute
Nephrology