Identification of the Causes for Chronic Hypokalemia: Importance of Urinary Sodium and Chloride Excretion.

Publication Title

The American journal of medicine

Document Type

Article

Publication Date

7-1-2017

Keywords

Acidosis, Renal Tubular; Adult; Anorexia Nervosa; Bartter Syndrome; Body Mass Index; Bulimia; Chlorides; Chronic Disease; Diuretics; Female; Gitelman Syndrome; Humans; Hypokalemia; Laxatives; Male; Prospective Studies; Sex Factors; Sodium; Substance-Related Disorders

Abstract

BACKGROUND: Uncovering the correct diagnosis of chronic hypokalemia with potassium (K

METHODS: Normotensive patients referred to our tertiary academic medical center for the evaluation of chronic hypokalemia were prospectively enrolled over 5 years. Clinical features, laboratory examinations-including blood and spot urine electrolytes, acid-base status, biochemistries, and hormones-as well as genetic analysis, were determined.

RESULTS: Ninety-nine patients with chronic normotensive hypokalemia (serum K

CONCLUSION: Besides body mass index, sex, and blood acid-base status, integrated interpretation of the urine Na

Area of Special Interest

Kidney & Diabetes

Specialty/Research Institute

Nephrology

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