Agonist Abs to TNF Receptor Family Members
Publication Title
6th Annual Immuno-Oncology 360°
Document Type
Abstract
Publication Date
2-28-2020
Abstract
This talk provides a summary of Abs to TNFR family members and their advances to the clinic (OX40, 4-1BB, CD27, GITR and CD40). In particular, OX40 agonists will be the focus of this talk and their effects on targeting T cells within the tumor microenvironment. Optimal dose and scheduling of OX40 agonists will also be reviewed.
Clinical Institute
Cancer
Specialty/Research Institute
Oncology
Specialty/Research Institute
Earle A. Chiles Research Institute