Intraoperative Ischemic Stroke in Elective Spine Surgery: A Retrospective Study of Incidence and Risk.

Publication Title

Spine (Phila Pa 1976)

Authors

Basem Ishak, Swedish Neuroscience Institute, Swedish Medical Center, Seattle, WA, USAFollow
Amir Abdul-Jabbar, Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USAFollow
Amit Singla, Swedish Neuroscience Institute, Seattle, Washington.Follow
Emre Yilmaz, Swedish Medical Center, Swedish Neuroscience InstituteFollow
Alexander von Glinski, Swedish Neuroscience Institute, Swedish Medical CenterFollow
Wyatt L. Ramey, Department of Neurosurgery, Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USAFollow
Ronen Blecher, Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USAFollow
Zane Tymchak, Swedish Neuroscience Institute, Seattle, Washington, USAFollow
Rod J Oskouian, Swedish Neuroscience Institute, Swedish Medical Center, Seattle, Washington, USAFollow
Jens R Chapman, Swedish Neuroscience InstituteFollow

Document Type

Article

Publication Date

1-15-2020

Keywords

Aged; Aged, 80 and over; Brain Ischemia; Cerebrospinal Fluid Leak; Comorbidity; Diabetes Mellitus; Dyslipidemias; Elective Surgical Procedures; Female; Hospital Mortality; Humans; Hypertension; Incidence; Intraoperative Complications; Male; Middle Aged; Retrospective Studies; Risk Factors; Smoking; Spine; Stroke

Abstract

STUDY DESIGN: . Retrospective study.

OBJECTIVE: . To determine incidence, risk factors, complications, and early postoperative outcome in patients with intraoperative ischemic stroke during elective spine surgery.

SUMMARY OF BACKGROUND DATA: . Overall, stroke is the fifth leading cause of death in the United States and the second leading cause of death worldwide. It can be a catastrophic event and the main cause of neurological disability in adults.

METHODS: . A retrospective review of the electronic medical records of patients who underwent elective spine surgery between January 2016 and November 2018 at a larger tertiary referral center was conducted. Patients with infection and neoplastic disease were excluded. Patient demographics, pre- and postoperative neurological status, surgical treatment, surgical time, blood loss, intraoperative abnormalities, risk factors, history of stroke, medical treatment, diagnostics, hospital stay, complications, and mortality were collected.

RESULTS: . Out of 5029 surgically treated patients receiving elective spine surgery, a total of seven patients (0.15%) were identified who developed an ischemic stroke during the surgical procedure. Patients were predominantly females (n = 6). Ischemic pontine stroke occurred in two patients. Further distributions of ischemic stroke were: left caudate nucleus, left posterior inferior cerebellar artery, left external capsule, left middle cerebral artery, and acute ischemic supratentorial spots. The main risk factors identified for intraoperative ischemic stroke include hypertension, diabetes, smoking, dyslipidemia, and possibly major intraoperative CSF leak. Three patients (43%) had neurological deficits which did not improve during hospital stay. Two patients recovered fully and two patients died. Therefore, in-hospital mortality rate of this subset of patients was 29%.

CONCLUSION: . With the increase of spinal procedures, it is important to identify patients at risk for having an ischemic stroke and to optimize their comorbidities preoperatively. Patients with intraoperative ischemic stroke carry a higher risk for morbidity and mortality during the index hospitalization.

LEVEL OF EVIDENCE: 4.

Clinical Institute

Neurosciences (Brain & Spine)

Specialty/Research Institute

Neurosciences

Specialty/Research Institute

Surgery