The NEALS primary lateral sclerosis registry.
Publication Title
Amyotroph Lateral Scler Frontotemporal Degener
Document Type
Article
Publication Date
11-1-2020
Keywords
oregon; portland; Adult; Amyotrophic Lateral Sclerosis; Humans; Motor Neuron Disease; Neurodegenerative Diseases; Registries; Retrospective Studies
Abstract
BACKGROUND AND OBJECTIVE: Primary lateral sclerosis (PLS) is a neurodegenerative disease characterized by progressive upper motor neuron dysfunction. Because PLS patients represent only 1 to 4% of patients with adult motor neuron diseases, there is limited information about the disease's natural history. The objective of this study was to establish a large multicenter retrospective longitudinal registry of PLS patients seen at Northeast ALS Consortium (NEALS) sites to better characterize the natural progression of PLS.
Area of Special Interest
Neurosciences (Brain & Spine)
Specialty/Research Institute
Neurosciences
