The NEALS primary lateral sclerosis registry.
Publication Title
Amyotroph Lateral Scler Frontotemporal Degener
Authors
Sabrina Paganoni
Fabiola De Marchi
James Chan
Sara K Thrower
Nathan P Staff
Neil Datta
Yaz Y Kisanuki
Vivian Drory
Christina Fournier
Erik P Pioro
Stephen A Goutman
Nazem Atassi
NEALS PLS Registry Study Group
Maryangel Jeon
Sarah Caldwell
Timothy Mcdonough
Caroline Gentile
Jianing Liu
Michelle Turner
Carol Denny
Kevin Felice
Misty Green
Stephanie Scarberry
Saad Abu-Saleh
Beatrice Nefussy
Debbie Hastings
Sangri Kim
Blake Swihart
Ximena Arcila-Londono
Daniel S Newman
Michael Silverman
Angela Genge
Kristiana Salmon
Lauren Elman
Leo Mccluskey
Kelly Almasy
Marc Gotkine
Kimberly Goslin, Providence ALS Center, Portland, OR, USA.Follow
Arlena Cummings, Providence ALS Center, Portland, OR, USA.Follow
Eli K Edwards, Providence ALS Center, Portland, OR, USA.
Michael Rivner
Kristy Bouchard
Brandy Quarles
Justin Kwan
Matthew Jaffa
Robert Baloh
Peggy Allred
David Walk
Samuel Maiser
Georgios Manousakis
Valerie Ferment
J Americo M Fernandes
Pariwat Thaisetthawatkul
Deborah Heimes
Melissa Phillips
Laura Sams
Melissa Kahler
Alecia Corcoran
Daniel G Larriviere
Sadie Chotto
Gracy Juba
Publication Date
11-1-2020
Keywords
oregon; portland; Adult; Amyotrophic Lateral Sclerosis; Humans; Motor Neuron Disease; Neurodegenerative Diseases; Registries; Retrospective Studies
Abstract
BACKGROUND AND OBJECTIVE: Primary lateral sclerosis (PLS) is a neurodegenerative disease characterized by progressive upper motor neuron dysfunction. Because PLS patients represent only 1 to 4% of patients with adult motor neuron diseases, there is limited information about the disease's natural history. The objective of this study was to establish a large multicenter retrospective longitudinal registry of PLS patients seen at Northeast ALS Consortium (NEALS) sites to better characterize the natural progression of PLS.
Area of Special Interest
Neurosciences (Brain & Spine)
Specialty/Research Institute
Neurosciences
