Elucidating Diversity in Obesity-Related Phenotypes Using Longitudinal and Multi-omic Approaches
Publication Title
Natural Products in Obesity and Diabetes
Document Type
Book
Publication Date
3-9-2022
Keywords
oregon; portland; chiles; genomics
Abstract
Human obesity remains one of the most challenging diseases to comprehensively characterize due to a highly complex interplay between genetics and lifelong environmental factors spanning diet, lifestyle, and other factors. Due to rapid technological advances and decreased experimental costs, it is now possible to routinely monitor millions of diverse biomolecules in the blood and other biological specimens over time in order to develop a better understanding of physiological trajectories underlying weight gain and loss as well as biomarkers for obesity-associated comorbidities. In this chapter, we will discuss the evolution of molecular ‘omic assays in the context of bariatric and metabolism research and how this field will likely continue to develop in the future.
Area of Special Interest
Kidney & Diabetes
Area of Special Interest
Digestive Health
Specialty/Research Institute
Earle A. Chiles Research Institute
Specialty/Research Institute
Endocrinology
Specialty/Research Institute
Nutrition
