A water-soluble alternative to simethicone for gastrointestinal endoscopy: Results of a clinical trial.

Publication Title

American journal of infection control

Authors

Teri S Mallard, Providence Swedish Medical Center, Seattle, WA.Follow
Sandra S Roswell, Providence Swedish Medical Center, Seattle, WA.Follow
Evan P Sylvester, Providence Swedish Medical Center, Seattle, WA.Follow
Cori L Ofstead
James M Scanlan, Providence HRA, Providence Health and Services; Swedish Center for Research and Innovation, Swedish Medical Center Seattle.Follow
John J Brandabur, Providence Sacred Heart Medical Center, Spokane, WA.Follow
Amarnath V Ramakrishnan, Providence Swedish Medical Center, Seattle, WA.Follow

Document Type

Article

Publication Date

4-25-2023

Keywords

washington; swedish

Abstract

During endoscopy, simethicone defoaming agents are commonly used to improve visualization, but they leave residues and impact drying. This clinical trial involved patients undergoing colonoscopy procedures with substantial bubbles that impeded mucosal wall visibility. As an alternative to simethicone, investigators evaluated a water-soluble, ginger-based gastrointestinal supplement (GI-Ease) that did not contain sugars, thickeners, or binding agents. In 112/114 cases (98%), bubbles were reduced sufficiently to allow visualization of the gastrointestinal tract, with no adverse events.

Area of Special Interest

Digestive Health

Specialty/Research Institute

Gastroenterology

Specialty/Research Institute

Surgery

DOI

10.1016/j.ajic.2023.04.166