Partial versus radical nephrectomy for complex renal mass: multicenter comparative analysis of functional outcomes (Rosula collaborative group).

Publication Title

Minerva Urol Nephrol

Document Type

Article

Publication Date

8-1-2023

Keywords

Humans; Kidney Neoplasms; Carcinoma, Renal Cell; Retrospective Studies; Nephrectomy; Kidney; washington; swedish urology

Abstract

BACKGROUND: Utility of partial nephrectomy (PN) for complex renal mass (CRM) is controversial. We determined the impact of surgical modality on postoperative renal functional outcomes for CRM.

METHODS: We retrospectively analyzed a multicenter registry (ROSULA). CRM was defined as RENAL Score 10-12. The cohort was divided into PN and radical nephrectomy (RN) for analyses. Primary outcome was development of de-novo estimated glomerular filtration rate (eGFR)/min/1.73 m

RESULTS: We analyzed 969 patients (RN=429/PN=540; median follow-up 24.0 months). RN patients had lower BMI (P

CONCLUSIONS: PN provides functional benefit in selected patients with CRM without significant increase in major complications compared to RN, and should be considered when technically feasible.

Area of Special Interest

Kidney & Diabetes

Specialty/Research Institute

Nephrology

Specialty/Research Institute

Urology

Specialty/Research Institute

Surgery

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