The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development.
Publication Title
medRxiv
Document Type
Article
Publication Date
10-3-2023
Keywords
washington; isb; genomics
Abstract
Non-coding variants increase risk of neuropsychiatric disease. However, our understanding of the cell-type specific role of the non-coding genome in disease is incomplete. We performed population scale (N=1,393) chromatin accessibility profiling of neurons and non-neurons from two neocortical brain regions
Area of Special Interest
Mental Health
Area of Special Interest
Neurosciences (Brain & Spine)
Area of Special Interest
Women & Children
Specialty/Research Institute
Behavioral Health
Specialty/Research Institute
Neurosciences
Specialty/Research Institute
Perinatology/Neonatology
DOI
10.1101/2023.10.02.23296067
COinS
