NCI Rectal-Anal Task Force consensus recommendations for design of clinical trials in rectal cancer.
Publication Title
Journal of the National Cancer Institute
Document Type
Article
Publication Date
12-6-2023
Keywords
oregon; chiles; United States; Humans; Consensus; National Cancer Institute (U.S.); Rectal Neoplasms; Chemoradiotherapy; Neoadjuvant Therapy
Abstract
The optimal management of locally advanced rectal cancer is rapidly evolving. The National Cancer Institute Rectal-Anal Task Force convened an expert panel to develop consensus on the design of future clinical trials of patients with rectal cancer. A series of 82 questions and subquestions, which addressed radiation and neoadjuvant therapy, patient perceptions, rectal cancer populations of special interest, and unique design elements, were subject to iterative review using a Delphi analytical approach to define areas of consensus and those in which consensus is not established. The task force achieved consensus on several areas, including the following
Clinical Institute
Digestive Health
Clinical Institute
Cancer
Specialty/Research Institute
Gastroenterology
Specialty/Research Institute
Oncology
DOI
10.1093/jnci/djad143
