Urethral Bulking With Polyacrylamide Hydrogel Compared With Other Treatments for Stress Urinary Incontinence: A Cost-Effectiveness Analysis.
Document Type
Article
Publication Date
3-1-2024
Publication Title
Obstetrics and gynecology
Keywords
Humans; Urinary Incontinence, Stress; Cost-Effectiveness Analysis; Acrylic Resins; Urethra; Treatment Outcome; Suburethral Slings; california; santa monica; sjci
Abstract
Our objective was to perform a cost-effectiveness analysis comparing polyacrylamide hydrogel urethral bulking with other surgical and nonsurgical treatments for stress urinary incontinence (SUI). We created a cost-effectiveness analysis using TreeAge Pro, modeling eight SUI treatments. Treatment with midurethral sling (MUS) had the highest effectiveness (1.86 quality-adjusted life-years [QALYs]), followed by polyacrylamide hydrogel (1.82 QALYs), with a difference (Δ 0.02/year) less than the minimally important difference for utilities of 0.03 annually. When the proportion of polyacrylamide hydrogel urethral bulking procedures performed in the office setting is greater than 58%, polyacrylamide hydrogel is a cost-effective treatment for SUI, along with pessary, pelvic floor physical therapy, and MUS. Although MUS is more effective and, therefore, the preferred SUI treatment, polyacrylamide hydrogel is a reasonable alternative depending on patient preferences and treatment goals.
Clinical Institute
Women & Children
Department
Urology
Department
Obstetrics & Gynecology
Recommended Citation
Chang, Olivia H; Shepherd, Jonathan P; Cadish, Lauren A; Wallace, Shannon L; St Martin, Brad; and Sokol, Eric R, "Urethral Bulking With Polyacrylamide Hydrogel Compared With Other Treatments for Stress Urinary Incontinence: A Cost-Effectiveness Analysis." (2024). Articles, Abstracts, and Reports. 8478.
https://digitalcommons.providence.org/publications/8478