Second Malignant Neoplasms Following Treatment for Hepatoblastoma: An International Report and Review of the Literature.

Publication Title

Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology

Document Type

Article

Publication Date

3-1-2024

Keywords

Humans; Hepatoblastoma; Prospective Studies; Risk Factors; Incidence; Neoplasms, Second Primary; Hematologic Neoplasms; Liver Neoplasms; washington; spokane; pshmc

Abstract

Treatment intensification has improved survival in patients with hepatoblastoma (HB); however, these treatments are associated with an increased risk of late effects, including second malignant neoplasms (SMNs). Data is limited regarding SMNs following HB treatment. Cases of SMNs following treatment for HB reported in the literature and from personal communication were analyzed to further assess this late effect. Thirty-eight patients were identified. The median age at diagnosis of HB was 16 months (range

Area of Special Interest

Women & Children

Specialty/Research Institute

Pediatrics

Specialty/Research Institute

Hematology

Specialty/Research Institute

Oncology

DOI

10.1097/MPH.0000000000002824

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