Body Mass Index and Mortality in Cardiogenic Shock.
Document Type
Article
Publication Date
3-25-2024
Publication Title
ASAIO journal (American Society for Artificial Internal Organs : 1992)
Keywords
oregon; portland
Abstract
We explored the association of body mass index (BMI) with mortality in cardiogenic shock (CS). Using the Cardiogenic Shock Working Group registry, we assessed the impact of BMI on mortality using restricted cubic splines in a multivariable logistic regression model adjusting for age, gender, and race. We also assessed mortality, device use, and complications in BMI categories, defined as underweight (40 kg/m2) using univariable logistic regression models. Our cohort had 3,492 patients with CS (mean age = 62.1 ± 14 years, 69% male), 58.0% HF-related CS (HF-CS), and 27.8% acute myocardial infarction (AMI) related CS. Body mass index was a significant predictor of mortality in multivariable regression using restricted cubic splines (p < 0.0001, p = 0.194 for nonlinearity). When stratified by categories, patients with healthy weight had lower mortality (29.0%) than obese (35.1%, p = 0.003) or severely obese (36.7%, p = 0.01). In HF-CS cohort, the healthy weight patients had the lowest mortality (21.7%), whereas it was higher in the underweight (37.5%, p = 0.012), obese (29.2%, p = 0.003), and severely obese (29.9%, p = 0.019). There was no difference in mortality among BMI categories in AMI-CS.
Clinical Institute
Cardiovascular (Heart)
Clinical Institute
Digestive Health
Department
Cardiology
Department
Gastroenterology
Department
Nutrition
Recommended Citation
Guglin, Maya; Zweck, Elric; Kanwar, Manreet; Sinha, Shashank S; Bhimaraj, Arvind; Li, Borui; Abraham, Jacob; Vallabhajosyula, Saraschandra; Hernandez-Montfort, Jaime; Kataria, Rachna; Burkhoff, Daniel; and Kapur, Navin K, "Body Mass Index and Mortality in Cardiogenic Shock." (2024). Articles, Abstracts, and Reports. 8592.
https://digitalcommons.providence.org/publications/8592