Clostridioides difficile Colitis.

Publication Title

The Surgical clinics of North America

Document Type

Article

Publication Date

6-1-2024

Keywords

washington; swedish

Abstract

Clostridioides difficile colitis is an important source of hospital-acquired diarrhea associated with antibiotic use. Symptoms are profuse watery diarrhea, typically following a course of antibiotics; however, some cases of fulminant disease may manifest with shock, ileus, or megacolon. Nonfulminant colitis is treated with oral fidaxomicin. C difficile colitis has a high potential for recurrence, and recurrent episodes are also treated with fidaxomicin. Bezlotoxumab is another medication that may be used in populations at high risk for further recurrence. Fulminant disease is treated with maximal medical therapy and early surgical consultation. Antibiotic stewardship is critical to preventing C difficile colitis.

Clinical Institute

Digestive Health

Specialty

Gastroenterology

Specialty

Infectious Diseases

Specialty

Surgery

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