GLP-1 receptor agonists for weight loss for perimenopausal and postmenopausal women: current evidence.

Publication Title

Current opinion in obstetrics & gynecology

Document Type

Article

Publication Date

4-1-2025

Keywords

Humans; Female; Postmenopause; Glucagon-Like Peptide-1 Receptor; Weight Loss; Perimenopause; Obesity; Middle Aged; Weight Gain; Glucagon-Like Peptide-1 Receptor Agonists; washington; swedish

Abstract

PURPOSE OF REVIEW: Glucagon-like peptide-1 receptor agonists (GLP-1 RA) have emerged as a leading pharmacologic for managing weight gain across most populations, including peri and postmenopausal women who frequently suffer from weight gain. There is a paucity of data about this specific population and how they respond to these medications. This review aims to discuss the data available about the use and effects of GLP-1 RAs in the peri and postmenopausal populations.

RECENT FINDINGS: GLP-1 RAs are consistently the most effective pharmacologic for weight loss and can be a valuable tool for use in peri and postmenopausal women.

SUMMARY: Additional research is needed to determine the risks and benefits and ideal use of GLP-1 RAs in peri and postmenopausal women.

Area of Special Interest

Women & Children

Area of Special Interest

Digestive Health

Specialty/Research Institute

Gastroenterology

Specialty/Research Institute

Pharmacy

Specialty/Research Institute

Obstetrics & Gynecology

DOI

10.1097/GCO.0000000000001015

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