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Submissions from 2022

Targeting mutant KRAS with TCR-gene therapy, E Tran

TCR-gene therapy targeting mutant KRAS, E Tran

Targeting mutant KRAS with TCR-gene therapy, Eric Tran

TILs Update, Eric Tran

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Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer. Reply., Eric Tran, Walter Urba, and Rom Leidner

The Impact of Remote Optimization of Guideline-Directed Medical Therapy in Patients with NYHA Stage II and III Heart Failure, MN Tran, Jacob Abraham, and See all authors in comments

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Center-Level Variation in Transplant Rates Following the Heart Allocation Policy Change., Zachary Tran, Roland A Hernandez, Josef Madrigal, Samuel T Kim, Arjun Verma, David G Rabkin, and Peyman Benharash

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Five Ways of Being to Impart on Managers., Sylvain Trepanier

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A Health Care System's Approach to Support Nursing Leaders in Mitigating Burnout Amid a COVID-19 World Pandemic., Sylvain Trepanier, Robin Henderson, and Arpan Waghray

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There's No Going Back: The Transformation of Psychiatry and Psychiatric Care Postpandemic., Robert L Trestman and Arpan Waghray

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A Nonrestrictive Approach to Fluoroquinolone Stewardship at Two Community Hospitals., William R Truong, Philip A Robinson, Richard C Beuttler, and Jason Yamaki

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Eight-year outcomes of aortic valve replacement with the Carpentier-Edwards PERIMOUNT Magna Ease valve., Steven Tsui, Michael Rosenbloom, James Abel, Jeffrey Swanson, Axel Haverich, Joseph Zacharias, Gilbert Schorlemmer, Gideon Cohen, Michael Moulton, and Rüdiger Lange

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The Effects of Magnesium Coadminstration During Treatment of Hypokalemia in the Emergency Department., Ashley Tuttle, Scott Fitter, Henry Hua, and Kayvan Moussavi

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ACID1-004: Euglycemic Ketoacidosis and Other Complications of SGLT2 Inhibitors, Katherine Tuttle

Advancing CKD Care Strategies for a Patient-Centered Team-Based Approach, Katherine Tuttle

Advancing Evidence-based Care in Diabetes & CKD, Katherine Tuttle

A Phase 2 Randomized Controlled Trial of Selonsertib in Moderate and Severe Diabetic Kidney Disease – Oral abstracts, Katherine Tuttle

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A Promising Weight-Loss Aid Emerges: Diabetes Drugs, Katherine Tuttle

Change in KDIGO Kidney Risk Category with Semaglutide Treatment – A Post-Hoc Analysis of the Sustain 6 Trial, Katherine Tuttle

Developments in managing DKD: Perspectives of a Nephrologist, Cardiologist & Diabetologist – a discussion of the main messages of the post hoc analysis of Figaro, Fidelio and Fidelity, Katherine Tuttle

Diabetic Kidney Disease: How Can We Improve Outcomes?, Katherine Tuttle

Effect of Dual Receptor Agonists on Cardiovascular System and the Kidney, Katherine Tuttle

Fatty Liver Disease in Diabetes: An Overlooked Complication, Katherine Tuttle

GLP-1 Receptor Agonists in Clinical Management of CKD & Diabetes, Katherine Tuttle

GLP-1 Receptor Agonists in Clinical Management of CKD & Diabetes, Katherine Tuttle

Glycemic Management in Diabetes and CKD, Katherine Tuttle

How to implement these heart failure guidelines in ambulatory patients around the world, Katherine Tuttle

Incretins in DKD. Mechanisms of action and clinical evidence, Katherine Tuttle

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Learnings from Throwing Paint at the Wall for COVID-19 with an SGLT2 Inhibitor., Katherine Tuttle

Long COVID Study, Katherine Tuttle

Targeting MR Overactivation, Katherine Tuttle

The Risks & Benefits of Finerenone, Katherine Tuttle

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Molecular mechanisms and therapeutic targets for diabetic kidney disease., Katherine Tuttle, Rajiv Agarwal, Charles E Alpers, George L Bakris, Frank C Brosius, Peter Kolkhof, and Jaime Uribarri

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Safety of Empagliflozin in Patients With Type 2 Diabetes and Chronic Kidney Disease: Pooled Analysis of Placebo-Controlled Clinical Trials., Katherine Tuttle, Adeera Levin, Masaomi Nangaku, Takashi Kadowaki, Rajiv Agarwal, Sibylle J Hauske, Amelie Elsäßer, Ivana Ritter, Dominik Steubl, Christoph Wanner, and David C Wheeler

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SGLT2 inhibitors as the bedrock of therapy for heart failure., Katherine Tuttle and Janani Rangaswami

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Incidence of Chronic Kidney Disease among Adults with Diabetes, 2015-2020., Katherine R Tuttle, Cami R Jones, Kenn B Daratha, Alain K Koyama, Susanne B Nicholas, Radica Z Alicic, O Kenrik Duru, Joshua J Neumiller, Keith C Norris, Nilka Ríos Burrows, and Meda E Pavkov

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Study Design of a Phase 2 Trial of the Aldosterone Synthase Inhibitor BI 690517 Alone and in Combination With Empagliflozin in Patients With Diabetic and Non-Diabetic CKD, Katherine Tuttle and See full list of authors in comments

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Moving from Evidence to Implementation of Breakthrough Therapies for Diabetic Kidney Disease., Katherine Tuttle, Leslie Wong, Wendy St Peter, Glenda Roberts, Janani Rangaswami, Amy Mottl, Alan S Kliger, Raymond C Harris, Patrick O Gee, Kevin Fowler, David Cherney, Frank C Brosius, Christos Argyropoulos, Susan E Quaggin, and Diabetic Kidney Disease Collaborative Task Force

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Are nephrometry scores accurate for the prediction of outcomes in patients with renal angiomyolipoma treated with robot-assisted partial nephrectomy? A multi-institutional analysis., Alessandro Uleri, Pietro Diana, Giovanni Lughezzani, Paolo Casale, Alberto Saita, Rodolfo Hurle, Massimo Lazzeri, Francesco Porpiglia, Cristian Fiori, Daniele Amparore, Paolo Verri, Giuseppe Rosiello, Alex Mottrie, Geert DE Naeyer, Ruben DE Groote, James R Porter, and Nicolomaria Buffi

Evolution of TCAR in my carotid practice: patient selection, learning curve, and lessons learned, Brant Ullery

Role of protocolization in the management of acute aortic syndromes, Brant Ullery

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Biolink Model: A universal schema for knowledge graphs in clinical, biomedical, and translational science., Deepak R Unni, Sierra A T Moxon, Michael Bada, Matthew Brush, Richard Bruskiewich, J Harry Caufield, Paul A Clemons, Vlado Dancik, Michel Dumontier, Karamarie Fecho, Gustavo Glusman, Jennifer J Hadlock, Nomi L Harris, Arpita Joshi, Tim Putman, Guangrong Qin, Stephen A Ramsey, Kent A Shefchek, Harold Solbrig, Karthik Soman, Anne E Thessen, Melissa A Haendel, Chris Bizon, Christopher J Mungall, and Biomedical Data Translator Consortium

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Routine frozen section during pancreaticoduodenectomy does not improve value-based care, Abhineet Uppal, Wade O Christopher, Trang Nguyen, Brooke Vuong, Stacey Stern, Juan Mejia, Roshanthi Weerasinghe, Evan Ong, and Anton J Bilchik

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The TARGIT-A Randomized Trial: TARGIT-IORT Versus Whole Breast Radiation Therapy: Long-Term Local Control and Survival., Jayant S Vaidya, Max Bulsara, Frederik Wenz, Elena Sperk, Samuele Massarut, Michael Alvarado, Norman R Williams, Chris Brew-Graves, Marcelle Bernstein, Dennis Holmes, Lorenzo Vinante, Steffi Pigorsch, Steinar Lundgren, Valery Uhl, David Joseph, Jeffrey S Tobias, and TARGIT-A authors

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Prevalence and Outcomes of Bicuspid Aortic Valve in Patients With Aneurysmal Sub-Arachnoid Hemorrhage: A Prospective Neurology Registry Report., Saarwaani Vallabhajosyula, Li-Tan Yang, Sarah C Thomas, Joseph J Maleszewski, Amber N Boler, Prabin Thapa, Maurice Enriquez-Sarano, Alejandro A Rabinstein, and Hector I Michelena

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Editorial: Mechanisms of Lymphocyte Exclusion in the Tumor Microenvironment., Rieneke van de Ven, Carlo Bifulco, Jason J Luke, and Sarah E Church

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Patient-Reported Outcomes for Fully Vaccinated COVID-19 Patients Over 6 Weeks: The Experiences of Clinical Breakthrough Cases., Keri B Vartanian, Daniel Fish, Benjamin Gronowski, Natalie Royal Kenton, and Ari Robicsek

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Patient experience and healthcare utilization for a COVID-19 telemedicine home monitoring program offered in English and Spanish., Keri B Vartanian, Megan Holtorf, Emily J Cox, George Diaz, Hargobind Khurana, Sherene Schlegel, Caroline Raganit, Brandon Ong, and Todd Czartoski

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Neoantigen-specific CD4 + T cells in human melanoma have diverse differentiation states and correlate with CD8 + T cell, macrophage, and B cell function, Joshua R Veatch, Sylvia M Lee, Carolyn Shasha, Naina Singhi, Julia L Szeto, Ata S Moshiri, Teresa S Kim, Kimberly Smythe, Paul Kong, Matthew Fitzgibbon, Brenda Jesernig, Shailender Bhatia, Scott S Tykodi, Evan T Hall, David R Byrd, John A Thompson, Venu G Pillarisetty, Thomas Duhen, A McGarry Houghton, Evan Newell, Raphael Gottardo, and Stanley R Riddell

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Robotic vs laparoscopic nephroureterectomy for upper tract urothelial carcinoma: a multicenter propensity-score matched pair "tetrafecta" analysis (ROBUUST collaborative group)., Alessandro Veccia, Umberto Carbonara, Hooman Djaladat, Reza Mehrazin, Daniel Eun, Adam C Reese, Xiaosong Meng, Robert Uzzo, Abhishek Srivastava, James R Porter, Jason Farrow, Marcus Jamil, Giuseppe Rosiello, Riccardo Tellini, Andrea Mari, Ali Al-Qathani, Koon Ho Rha, Linhui Wang, Riccardo Mastroianni, Matteo Ferro, Ottavio De Cobelli, Kevin Hakimi, Fabio Crocerossa, Alireza Ghoreifi, Giovanni Cacciamani, Amit Amit S Bhattu, Alexandre Mottrie, Firas Abdollah, Andrea Minervini, Zhenjie Wu, Giuseppe Simone, Ithaar H Derweesh, Mark L Gonzalgo, Vitaly Margulis, Chandru P Sundaram, and Riccardo Autorino

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Single-access for Impella-supported percutaneous coronary intervention using a sheathless technique with an 8 Fr guide., Louis Verreault-Julien, Nikoloz Shekiladze, Jason Wollmuth, and Stéphane Rinfret

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Strategies for Reducing Vascular and Bleeding Risk for Percutaneous Left Ventricular Assist Device-supported High-risk Percutaneous Coronary Intervention., George W Vetrovec, Amir Kaki, Jason Wollmuth, and Thom G Dahle

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Clinical application of the "sellar barrier's concept" for predicting intraoperative CSF leak in endoscopic endonasal surgery for pituitary adenomas with a machine learning analysis., J F Villalonga, D Solari, R Cuocolo, V De Lucia, L Ugga, C Gragnaniello, J I Pailler, A Cervio, A Campero, L M Cavallo, and P Cappabianca

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Attractor-Specific and Common Expression Values in Random Boolean Network Models (with a Preliminary Look at Single-Cell Data)., Marco Villani, Gianluca D'Addese, Stuart A Kauffman, and Roberto Serra

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Premature Death in Kidney Transplant Recipients: The Time for Trials is Now., Amanda J Vinson, Sunita Singh, Steven Chadban, David Cherney, Osama Gaber, John S Gill, Erika Helgeson, Charles A Herzog, Meg Jardine, Vivekanand Jha, Bertram L Kasiske, Roslyn B Mannon, Erin D Michos, Amy K Mottl, Kristin Newby, Prabir Roy-Chaudhury, Deirdre Sawinski, Adnan Sharif, Vikas S Sridhar, Katherine Tuttle, David M Vock, and Arthur Matas

"Let the games begin! How to use action to create fun meeting and learning environments", Mary Volenec

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Basic Science Session 1. Biomarkers for Psoriatic Arthritis Treatment Response and Joint Damage Progression: An Update on 2 Industry-GRAPPA Projects., James C Waddington, Orla Coleman, Philip Mease, Vinod Chandran, Denis O'Sullivan, Oliver FitzGerald, and Stephen R Pennington

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CTNI-51. FEASIBILITY AND SAFETY OF NEUROSURGICAL RESECTION AND INTRA-OPERATIVE RADIATION THERAPY USING THE XOFT AXXENT ELECTRONIC BRACHYTHERAPY SYSTEM AND BEVACIZUMAB IN RECURRENT GLIOBLASTOMA, Naveed Wagle, Garni Barkhoudarian, Lisa Chaiken, Robert Wollman, Akanksha Sharma, Jose Carrillo, Minhdan Nguyen, Judy D Truong, Jared Chow, Emma Chacon, and Santosh Kesari

Geno4ME: establishment of an equitable whole-genome sequencing-based platform for clinical screening in a large healthcare system, Josiah Wagner, I A. Lucas-Beckett, K R. Emery, B A. Cosgrove, John T. Welle, K Jade, N D. Wagner, J Rinaldi, Lindsay Dickey, K G. Jones, L Yuan, E M. Shull, J Clemens, Keri Vartanian, A T. Magis, M B. Campbell, Brian Piening, Carlo Bifulco, and Ora K. Gordon

Clinical Performance of Comprehensive Genomic Profiling Using a Wide Range of Input Quantities and Solid Tumor Tissue Types, Josiah Wagner, S Reynolds, A Dowdell, E Shull, J Welle, M Pukay, R Rattray, C Moung-Wen, T Ward, M Campbell, C Bifulco, and B Piening

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Novel Therapeutics and Treatment Strategies for Medullary Thyroid Cancer., Evan Walgama, Naifa Busaidy, and Mark Zafereo

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Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction., Dennis D Wang, Sophia Airhart, Bo Zhou, Laura M Shireman, Siyi Jiang, Carolina Melendez Rodriguez, James N Kirkpatrick, Danny D Shen, Rong Tian, and Kevin D O'Brien

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Another Year Has Come to an End., Jeffrey C Wang, Jens R Chapman, and Karsten Wiechert

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"Special Collections: Creating Order in the Chaos"., Jeffrey C Wang, Karsten Wiechert, and Jens R Chapman

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Three-Year Follow-Up of KTE-X19 in Patients With Relapsed/Refractory Mantle Cell Lymphoma, Including High-Risk Subgroups, in the ZUMA-2 Study., Michael Wang, Javier Munoz, Andre Goy, Frederick L Locke, Caron A Jacobson, Brian T Hill, John M Timmerman, Houston Holmes, Samantha Jaglowski, Ian W Flinn, Peter A McSweeney, David B Miklos, John M Pagel, Marie José Kersten, Krimo Bouabdallah, Rashmi Khanal, Max S Topp, Roch Houot, Amer Beitinjaneh, Weimin Peng, Xiang Fang, Rhine R Shen, Rubina Siddiqi, Ioana Kloos, and Patrick M Reagan

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Understanding the Role of Advanced Practice Providers & How They Influence Health Policy & Practice, Cindi Warburton and Justin Gill

Streamlining Solid Tumor Comprehensive Genomic Profiling Workflows Using Learned Variant and Sequencing Noise Autoclassification, Thomas Ward, S Reynolds, J Wagner, N Naidoo, E Shull, John Welle, R Rattray, C Moung-Wen, Mary Campbell, Brian Piening, and Carlo Bifulco

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Deep Learning System Boosts Radiologist Detection of Intracranial Hemorrhage., Roshan Warman, Anmol Warman, Pranav Warman, Andrew Degnan, Johan Blickman, Varun Chowdhary, Dev Dash, Rohit Sangal, Jason Vadhan, Tulio Bueso, Thomas Windisch, and Gabriel Neves

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Conclusions and recommendations of an AHPBA-commissioned assessment of strengths, weaknesses, opportunities, and threats facing fellowship training in HPB surgery., Susanne G Warner, Michele Babicky, Adnan Alseidi, Brendan Visser, and AHPBA SWOT Taskforce

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Prospective Case-control Study of Contact Tracing Speed for Emergency Department-based Contact Tracers., Sean C Weaver, Samuel S Byrne, Hollianne Bruce, Olivia L Vargas, and Thomas E Robey

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Identification of clinically actionable biomarkers via routine comprehensive genomic profiling across a large community health system, Roshanthi Weerasinghe, Ryan Meng, Alexa K Dowdell, Bela Bapat, Ann Vita, Brock Schroeder, Alisha Stein, Lauren Harold, Mark Schmidt, Shu-Ching Chang, Thomas R. Ward, Josiah T Wagner, Stanley Piotrowski, Phillip G. Febbo, Carlo Bifulco, and Brian D. Piening

Identification of clinically actionable biomarkers via routine comprehensive genomic profiling across a large community health system., Rosohanthi K. Weersinghe, Ryan Meng, Alexa K. Dowdell, Bela Bapat, Ann Vita, Brock Schroeder, Alisha Stein, Lauren Harold, Mark Schmidt, Shu-Ching Chang, Thomas Ward, Josiah Wagner, Stanley Piotrowski, Phillip G. Febbo, Carlo Bifulco, and Brian Piening

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Germline biomarkers predict toxicity to anti-PD1/PDL1 checkpoint therapy., Joanne Weidhaas, Nicholas Marco, Aaron W Scheffler, Anusha Kalbasi, Kirk Wilenius, Emily Rietdorf, Jaya Mini Gill, Mara Heilig, Caroline Desler, Robert K Chin, Tania Kaprealian, Susan McCloskey, Ann Raldow, Naga P Raja, Santosh Kesari, Jose Carrillo, Alexandra Drakaki, Mark Scholz, and Donatello Telesca

Enriching for tumor-reactive CD8 TIL using CD39/103 markers: Clinical implications, A Weinberg

Isolating/Expanding the Entire TIL Repertoire of Tumor-Reactive CD8 T Cells for Cell Therapy in H&N Cancer, Andrew Weinberg

Identifying tumor-reactive CD8+ TIL in patients with solid malignancies: clinical implications, Andrew D Weinberg

T Cell Agonists, Andrew D Weinberg

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Predicting Long-term Disability in Multiple Sclerosis: A Narrative Review of Current Evidence and Future Directions., Bianca Weinstock-Guttman, Maria Pia Sormani, and P Repovic

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Accepting social e-cigarette behaviors among fraternity members found utilizing egocentric network analysis, AC Welch, MS Patterson, Candice L. Wilshire, H Kathuria, CR Gilbert, and JA Gorden

The role of ego networks for college fraternity members who use e-cigarettes, AC Welch, MS Patterson, Candice L. Wilshire, H Kathuria, CR Gilbert, and JA Gorden

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Design and Validation of a Whole-Genome Sequencing- Based Assay for Population Health, John Welle, Brian D. Piening, Josiah T Wagner, Isabelle Lucas-Beckett, T Ward, Benjamin Cosgrove, Eric Shull, R Rattray, Marina Pukay, M Ricks, Kimberly K Childers, Jennifer M Linehan, Mary Campbell, Ora K Gordon, and Carlo Bifulco

Design and Validation of a Whole-Genome SequencingBased Assay for Population Health, John Welle, Brian Piening, Josiah Wagner, I Lucas-Beckett, Thomas Ward, B Cosgrove, Eric Shull, R Rattray, Marina Pukay, Milena Ricks, K Childers, J Linehan, M Campbell, Ora Gordon, and Carlo Bifulco

Racial Differences in Patients with Spontaneous Coronary Artery Dissection: A Report of the ISCAD Registry, BJ Wells, LM Tam, and See all authors in comments

Migraine Headache in Patients with SCAD: A Report of the iSCAD Registry, BJ Wells, L Tam, and See all authors in comments

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Adipocytes Encapsulating Telratolimod Recruit and Polarize Tumor-Associated Macrophages for Cancer Immunotherapy., Di Wen, Tingxizi Liang, Guojun Chen, Hongjun Li, Zejun Wang, Jinqiang Wang, Ruxing Fu, Xiao Han, Tianyuan Ci, Yuqi Zhang, Peter Abdou, Ruoxin Li, Linlin Bu, Gianpietro Dotti, and Zhen Gu

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Impacts of Healthy U: A cluster-randomized control trial of a sexual health education app developed for justice-involved male youth, Staci J. Wendt, Jonathan Nakamoto, Pamela MacDougall, and Anthony Petrosino

Families in palliative and end-of-life care, K Widger and Melissa Robinson

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Specialist-beliefs often prevent a genuinely effective approach to chronic low back pain., Karsten Wiechert, Jens R Chapman, and Jeffrey C Wang

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Spine Apps: Creating Order in the Chaos?, Karsten Wiechert, Jens R Chapman, and Jeffrey C Wang

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Spine Surgery has Always had Multi-Specialty Roots: Time for Nonoperative Spine Care to Catch up and Join the Club., Karsten Wiechert, Jens R Chapman, and Jeffrey C Wang

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How does gender-affirming hormone therapy affect QOL in transgender patients?, Sarah Wilhelm, Gary Kelsberg, and Sarah Safranek

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778 Botensilimab, a novel innate/adaptive immune activator, plus or minus balstilimab (anti-PD-1) in “cold” and I-O refractory metastatic solid tumors, Breelyn Wilky, Kim Margolin, Rachel E Sanborn, Steven O'Day, and See full list of authors in comments

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Healthy aging and the human gut microbiome: why we cannot just turn back the clock., Tomasz Wilmanski, Sean M Gibbons, and Nathan D Price

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Heterogeneity in statin responses explained by variation in the human gut microbiome., Tomasz Wilmanski, Sergey A Kornilov, Christian Diener, Matthew P Conomos, Jennifer C Lovejoy, Paola Sebastiani, Eric S Orwoll, Leroy Hood, Nathan D Price, Noa Rappaport, Andrew T Magis, and Sean M Gibbons

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Comparing Initial Surgery versus Fibrinolytics for Pleural Space Infections: A Retrospective Multicenter Cohort Study., Candice L. Wilshire, Anee Sophia Jackson, Austin M Meggyesy, Kerrie E Buehler, Shu-Ching Chang, Leah C Horslen, Joshua R Rayburn, Carson C Fuller, Alexander S Farivar, Adam J Bograd, Brian Louie, Eric Vallieres, Ralph W Aye, Christopher R Gilbert, and Jed A Gorden

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Lower paraspinous muscle index at first thoracentesis is associated with poor survival in non-small cell lung cancer, Candice L. Wilshire, AM Meggyesy, JA Gorden, and CR Gilbert

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Chronic Fatigue Predicts Hospital Nurse Turnover Intentions, Elizabeth Winokur, Dana N Rutledge, and Sara Douville

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Climate, Health, and Nursing Tool (CHANT): A confirmatory factor analysis., Anna Winquist, Elizabeth Schenk, Cara Cook, Shanda Demorest, and Ekaterina Burduli

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Early experience with UGN-101 for the treatment of upper tract urothelial cancer - A multicenter evaluation of practice patterns and outcomes., Solomon L Woldu, Craig Labbate, Katie S Murray, Kyle Rose, Wade Sexton, Isamu Tachibana, Hristos Kaimakliotis, Joseph Jacob, Rian Dickstein, Jennifer Linehan, Alan Nieder, Marc A Bjurlin, Mitchell Humphreys, Saum Ghodoussipor, Marcus L Quek, Michael O'Donnell, Brian H Eisner, Adam S Feldman, Surena F Matin, and Yair Lotan

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RTX-KG2: a system for building a semantically standardized knowledge graph for translational biomedicine., E C Wood, Amy K Glen, Lindsey G Kvarfordt, Finn Womack, Liliana Acevedo, Timothy S Yoon, Chunyu Ma, Veronica Flores, Meghamala Sinha, Yodsawalai Chodpathumwan, Arash Termehchy, Jared C Roach, Luis Mendoza, Andrew S Hoffman, Eric W Deutsch, David Koslicki, and Stephen A Ramsey