Metachronous metastasis of renal cell carcinoma to the contralateral ureter 8 years after nephrectomy presenting as hydronephrosis.

Publication Title

Urol Case Rep

Authors

• Kolos K Nagy
• Caroline J Cushman
• Jason R Jesudass
• Seshadri D Thirumala, Department of Pathology, Covenant Medical Center, Lubbock, TX, USAFollow
• Brian E Nicholson, Department of Urology, Covenant Medical Center, Lubbock, TX, USAFollow
• Donald P Quick, Department of Hematology and Oncology, Covenant Medical Center, Lubbock, TX, USAFollow

Document Type

Article

Publication Date

5-1-2026

Keywords

texas; covenant; lubbock

Abstract

Renal cell carcinoma (RCC) is characterized by a potential for unpredictable metastatic pattern and a capacity for delayed recurrence years after apparently curative surgical resection. Metastatic spread most commonly involves the lungs, bone, and lymph nodes, and involvement of the contralateral ureter is exceptionally rare, particularly when occurring as a true metachronous lesion years after primary tumor resection. Herein, we report a case of isolated contralateral distal ureteral metastasis identified 8 years after radical nephrectomy for RCC.

Area of Special Interest

Cancer

Area of Special Interest

Kidney & Diabetes

Specialty/Research Institute

Oncology

Specialty/Research Institute

Urology

Specialty/Research Institute

Nephrology

DOI

10.1016/j.eucr.2026.103447