Molecular malignancy in melanocytic lesions

Authors

Hui Wang
Christopher Roberts
Krishna Maddula
Zhenquiang Lu
Tom Vasicek
BJ Kerns
Bruce E. Seligmann
Dave S B Hoon, Department of Translational Molecular Medicine, John Wayne Cancer Institute (JWCI) at Providence Saint John's Health Center, Santa Monica, CA 90404 USA.Follow

Document Type

Patent

Publication Date

6-24-2013

Abstract

Disclosed are methods for determining whether a melanocyte-containing sample (such as a nevus or other pigmented lesion) is benign or a primary melanoma. These methods can include detecting (at the molecular level, e.g., mRNA, miRNA, or protein) the expression of at least two disclosed genes in a biological sample obtained from a subject. Also provided are arrays and kits that can be used with the methods.

Area of Special Interest

Cancer

Location

United States

Comments

Patent Number: 9,758,829

Publication Title

United States Patent and Trademark Office, www.uspto.gov

Assignee

HTG Molecular Diagnostics, Inc. (Tucson, AZ); John Wayne Cancer Institute (Santa Monica, CA)

Family ID

49769469

Serial Number

14/405,739

Tech ID

12-JWCI-068