Methods and compositions for inducing an immune response to EGFRvIII
Document Type
Patent
Publication Date
11-25-2015
Abstract
The present invention relates to methods of inducing a T-cell response against a EGFRvIII in a subject. These method comprise administering to a subject a composition which expresses at least one immunogenic polypeptide, the amino acid sequence of which comprise a plurality of EGFRvIII polypeptide sequences, the sequence of which each comprise EEKKGNYV (SEQ ID NO: 3), and/or administering the polypeptide itself.
Assignee
ADURO BIOTECH, INC. (Berkeley, CA); PROVIDENCE HEALTH & SERVICES--OREGON (Portland, OR)
Family ID
46084412
Serial Number
14/952,470
Tech ID
10-03-INV
COinS
Comments
Patent Number: 9,775,891