Methylation of estrogen receptor alpha and uses thereof

Authors

Dave S B Hoon, Department of Translational Molecular Medicine, John Wayne Cancer Institute (JWCI) at Providence Saint John's Health Center, Santa Monica, CA 90404 USA.Follow

Document Type

Patent

Publication Date

3-29-2007

Abstract

Methods for diagnosis, prognosis, and treatment of cancer based on the methylation status of the ER-.alpha. gene promoter are disclosed. Methylation of the ER-.alpha. gene promoter is indicative of cancer and unfavorable prognosis. The cancer can be treated with a demethylation agent.

Clinical Institute

Cancer

Specialty/Research Institute

Oncology

Location

United States

Comments

Patent Number: 7,829,283

Assignee

John Wayne Cancer Institute (Santa Monica, CA)

Family ID

38625489

Serial Number

11/693,673

Tech ID

06-JWCI-017