Use of ID4 for diagnosis and treatment of cancer
Methods for diagnosis and treatment of cancer using ID4 are disclosed. Specifically, epigenetic inactivation of ID4 in colorectal carcinomas and breast correlates with poor differentiation and unfavorable prognosis. Further, aberrant hypermethylation of ID4 gene promoter region increases risk of metastasis in colorectal and breast cancer.
John Wayne Cancern Institute (Santa Monica, CA)
Hoon, Dave S B and Umetani, Naoyuki, "Use of ID4 for diagnosis and treatment of cancer" (2006). Technology Transfer - Patents. 44.