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Submissions from 2023

Minimal residual disease by circulating tumor DNA as a biomarker of recurrence free survival in resected high-risk melanoma patients treated with mRNA-4157/V940, a personalized cancer vaccine, and pembrolizumab, Matteo S. Carlino, Matthew H. Taylor, and See all authors in comments

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CT275 / 15 - Phase 1 clinical update of allogeneic invariant natural killer T cells (iNKTs), agenT-797, alone or in combination with pembrolizumab or nivolumab in patients with advanced solid tumors, B Carneiro

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CT275 / 15 - Phase 1 clinical update of allogeneic invariant natural killer T cells (iNKTs), agenT-797, alone or in combination with pembrolizumab or nivolumab in patients with advanced solid tumors, B Carneiro, Rachel E Sanborn, and See full list of authors in comments

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New Technology for the Breast Surgeon., Michele Carpenter and Julie Le

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Partial or radical nephrectomy for complex renal mass: a comparative analysis of oncological outcomes and complications from the ROSULA (Robotic Surgery for Large Renal Mass) Collaborative Group., Clara Cerrato, Devin Patel, Riccardo Autorino, Giuseppe Simone, Bo Yang, Robert Uzzo, Francesco Porpiglia, Umberto Capitanio, James Porter, Alp Tuna Beksac, Andrea Minervini, Alessandro Antonelli, Maria Angela Cerruto, Clayton Lau, Akbar Ashrafi, Daniel Eun, Alexandre Mottrie, Carmen Mir, Margaret F Meagher, Dhruv Puri, Mimi Nguyen, Sohail Dhanji, Franklin Liu, Savio D Pandolfo, Alexander Kutikov, Francesco Montorsi, Inderbir S Gill, Chandru Sundaram, Jihad Kaouk, and Ithaar H Derweesh

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Safety and Efficacy Outcomes From a Single-Center Study of Image-Guided Percutaneous Microwave Ablation for Primary and Metastatic Lung Malignancy., Stephen M Chan, Peter J Julien, Peter Kaganjo, Robert McKenna, Charles Forscher, Ronald Natale, Robert N Wolfe, Kristi Butenschoen, Rene J Siegel, and James Mirocha

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Secondary Breast Angiosarcoma After a Primary Diagnosis of Breast Cancer: A Retrospective Analysis of the Surveillance, Epidemiology, and End Results (SEER) Database., Bonny Chau, Elizabeth T Loggers, Lee D Cranmer, Harveshp Mogal, Jeremy M Sharib, Edward Y Kim, Stephanie K Schaub, Kelly G Paulson, Hannah M Linden, Jennifer M Specht, Janice N Kim, Sara H Javid, and Michael J Wagner

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A heterodimer of α and β hemoglobin chains functions as an innate anticancer agent., Maharrish Chelladurai, Dan Xu, Sivan Izraely, Shlomit Ben-Menachem, Roman Bengaiev, Orit Sagi-Assif, Weirong Yuan, Metsada Pasmanik Chor, Dave S Hoon, Wuyuan Lu, and Isaac P Witz

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Liver Metastases and Immune Checkpoint Inhibitor Efficacy in Patients With Refractory Metastatic Colorectal Cancer: A Secondary Analysis of a Randomized Clinical Trial., Eric X Chen, Jonathan M Loree, Emma Titmuss, Derek J Jonker, Hagen F Kennecke, Scott Berry, Felix Couture, Chaudharry E Ahmad, John R Goffin, Petr Kavan, Mohammed Harb, Bruce Colwell, Setareh Samimi, Benoit Samson, Tahir Abbas, Nathalie Aucoin, Francine Aubin, Sheryl Koski, Alice C Wei, Dongsheng Tu, and Chris J O'Callaghan

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Mosaic chromosomal alterations is associated with increased lung cancer risk: insight from the INTEGRAL-ILCCO cohort analysis., Chao Cheng, Wei Hong, Yafang Li, Xiangjun Xiao, James McKay, Younghun Han, Jinyoung Byun, Bo Peng, Demetrios Albanes, Stephen Lam, Adonina Tardon, Chu Chen, Stig E Bojesen, Maria T Landi, Mattias Johansson, Angela Risch, Heike Bickeböller, H-Erich Wichmann, David C Christiani, Gad Rennert, Susanne Arnold, Gary E Goodman, John K Field, Michael Pa Davies, Sanjay S Shete, Loic Le Marchand, Geoffrey Liu, Rayjean J Hung, Angeline S Andrew, Lambertus A Kiemeney, Meng Zhu, Hongbing Shen, Shan Zienolddiny, Kjell Grankvist, Mikael Johansson, Angela Cox, Yun-Chul Hong, Jian-Min Yuan, Philip Lazarus, Matthew B Schabath, Melinda C Aldrich, Paul Brennan, Yong Li, Olga Gorlova, Ivan Gorlov, and Christopher I Amos

HB-300, a novel arenavirus-based cancer immunotherapy in patients with metastatic castration-resistant prostate cancer, D Chism, Brendan Curti, and See all authors in comments

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Amivantamab plus lazertinib in osimertinib-relapsed EGFR-mutant advanced non-small cell lung cancer: a phase 1 trial., Byoung Chul Cho, Dong-Wan Kim, Alexander I Spira, Jorge E Gomez, Eric B Haura, Sang-We Kim, Rachel E Sanborn, Eun Kyung Cho, Ki Hyeong Lee, Anna Minchom, Jong-Seok Lee, Ji-Youn Han, Misako Nagasaka, Joshua K Sabari, Sai-Hong Ignatius Ou, Patricia Lorenzini, Joshua M Bauml, Joshua C Curtin, Amy Roshak, Grace Gao, John Xie, Meena Thayu, Roland E Knoblauch, and Keunchil Park

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Two-Stage Deep-Learning Classifier for Diagnostics of Lung Cancer Using Metabolites., Ashvin Choudhary, Jianpeng Yu, Valentina L Kouznetsova, Santosh Kesari, and Igor F Tsigelny

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Belzutifan plus cabozantinib for patients with advanced clear cell renal cell carcinoma previously treated with immunotherapy: an open-label, single-arm, phase 2 study., Toni K Choueiri, David F McDermott, Jaime Merchan, Todd M Bauer, Robert Figlin, Elisabeth I Heath, M Dror Michaelson, Edward Arrowsmith, Anishka D'Souza, Song Zhao, Ananya Roy, Rodolfo Perini, Donna Vickery, and Scott S Tykodi

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Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis., William Chour, Jongchan Choi, Jingyi Xie, Mary E Chaffee, Thomas M Schmitt, Kathryn Finton, Diana C DeLucia, Alexander M Xu, Yapeng Su, Daniel G Chen, Rongyu Zhang, Dan Yuan, Sunga Hong, Alphonsus H C Ng, Jonah Z Butler, Rick A Edmark, Lesley C Jones, Kim M Murray, Songming Peng, Guideng Li, Roland K Strong, John K Lee, Jason D Goldman, Philip D Greenberg, and James R Heath

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Clinician-Performed Thyroid Fine Needle Aspiration With On-Site Review Improves Diagnostic Yield., Isabelle Chu, Oliver Bellevue, Joseph C Sniezek, and Nuria Perez-Reyes

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Patterns of utilization and clinical adoption of 0.35 Tesla MR-guided radiation therapy in the United States - Understanding the transition to adaptive, ultra-hypofractionated treatments., Michael D Chuong, Mary Ann Clark, Lauren E Henke, Amar U Kishan, Lorraine Portelance, Parag J Parikh, Michael F Bassetti, Himanshu Nagar, Stephen A Rosenberg, Minesh P Mehta, Tamer Refaat, Justin M Rineer, Adam Smith, Steven Seung, Bassem I Zaki, Martin Fuss, and Raymond H Mak

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BETA prime: a first-in-man phase 1 study of AdAPT-001, an armed oncolytic adenovirus for solid tumors., Anthony P Conley, Christina L Roland, Alberto Bessudo, Brian R Gastman, Victoria M Villaflor, Christopher Larson, Tony R Reid, Scott Caroen, Bryan Oronsky, Meaghan Stirn, Jeannie Williams, Erica Burbano, Angelique Coyle, Minal A Barve, Naveed Wagle, Nacer Abrouk, and Santosh Kesari

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Abstract CT123: Trial in progress: First-in-human immunotherapy-trio for advanced head and neck squamous cell carcinoma, MA Couey, Matthew H Taylor, William L. Redmond, Brady Bernard, Richard Bryan Bell, Carlo Bifulco, Brian D. Piening, Walter Urba, Bernard A Fox, and Rom Leidner

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Phase 1 dose-escalation study of SEA-CD40: a non-fucosylated CD40 agonist, in advanced solid tumors and lymphomas., Andrew L Coveler, David C Smith, Tycel Phillips, Brendan D Curti, Sanjay Goel, Amitkumar N Mehta, Timothy M Kuzel, Svetomir N Markovic, Olivier Rixe, David L Bajor, Thomas F Gajewski, Martin Gutierrez, Hun Ju Lee, Ajay K Gopal, Paolo Caimi, Elisabeth I Heath, John A Thompson, Sahar Ansari, Celine Jacquemont, Ariel Topletz-Erickson, Peigen Zhou, Michael W Schmitt, and Juneko E Grilley-Olson

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Disparity in Breast Cancer Care: Current State of Access to Screening, Genetic Testing, Oncofertility, and Reconstruction., Angelena Crown, Soudabeh Fazeli, Allison W Kurian, Daniela A Ochoa, and Kathie-Ann Joseph

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Pregnancy-associated breast cancer: does timing of presentation affect outcome?, Angelena Crown, Damian McCartan, Michael A Curry, Sujata Patil, Sabrina Kamer, Shari Goldfarb, and Mary L Gemignani

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Comparison of robotic versus laparoscopic right colectomy node retrieval in the obese population., Karleigh R Curfman, Jessica M Gowing, Ruben M Lesnick, James M Scanlan, Ulrik G Wallin, John A Griffin, and Laila Rashidi

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Temporary Knockdown of p53 During Focal Limb Irradiation Increases the Development of Sarcomas., Andrea R Daniel, Chang Su, Nerissa T Williams, Zhiguo Li, Jianguo Huang, Omar Lopez, Lixia Luo, Yan Ma, Lorraine da Silva Campos, Sara R Selitsky, Jennifer L Modliszewski, Siyao Liu, Rosa Hernansaiz-Ballesteros, Yvonne M Mowery, Diana M Cardona, Chang-Lung Lee, and David G Kirsch

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Capicua (CIC) mutations in gliomas in association with MAPK activation for exposing a potential therapeutic target., Sourat Darabi, Joanne Xiu, Timothy Samec, Santosh Kesari, Jose Carrillo, Sonikpreet Aulakh, Kyle M Walsh, Soma Sengupta, Ashley Sumrall, David Spetzler, Michael Glantz, and Michael J Demeure

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Practical considerations when providing palliative care to patients with neuroendocrine tumors in the context of routine disease management or hospice care., Jaydira Del Rivero, Josh Mailman, Michael W Rabow, Jennifer A Chan, Sarah Creed, Hagen F Kennecke, Janice Pasieka, Jennifer Zuar, Simron Singh, and Lauren Fishbein

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Bempegaldesleukin Plus Nivolumab in Untreated Advanced Melanoma: The Open-Label, Phase III PIVOT IO 001 Trial Results., Adi Diab, Helen Gogas, Shahneen Sandhu, Georgina V Long, Paolo A Ascierto, James Larkin, Mario Sznol, Fabio Franke, Tudor E Ciuleanu, Caio Pereira, Eva Muñoz Couselo, Fernanda Bronzon Damian, Michael Schenker, Aldo Perfetti, Celeste Lebbe, Gaëlle Quéreux, Friedegund Meier, Brendan Curti, Carlos Rojas, Yull Arriaga, Haisu Yang, Ming Zhou, Shruthi Ravimohan, Paul Statkevich, Mary A Tagliaferri, and Nikhil I Khushalani

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Immunotherapy for brain metastases and primary brain tumors., Anna M Di Giacomo, Maximilian J Mair, Michele Ceccarelli, Andrea Anichini, Ramy Ibrahim, Michael Weller, Michael Lahn, Alexander M M Eggermont, Bernard Fox, and Michele Maio

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Identification and surveillance of rare relapse-initiating stem cells during complete remission post-transplantation., Marios Dimitriou, Teresa Mortera-Blanco, Magnus Tobiasson, Stefania Mazzi, Madeleine Lehander, Kari Högstrand, Mohsen Karimi, Gunilla Walldin, Monika Jansson, Sofie Vonlanthen, Per Ljungman, Saskia M C Langemeijer, Tetsuichi Yoshizato, Eva S Hellstrom-Lindberg, Petter S Woll, and Sten Eirik W Jacobsen

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MDR1-EXPRESSING CD4, Anthony Di Roio, Margaux Hubert, Laurie Besson, Marion Bossennec, Céline Rodriguez, Yenkel Grinberg-Bleyer, Guilhem Lalle, Lyvia Moudombi, Raphael Schneider, Cyril Degletagne, Isabelle Treilleux, Daniel J Campbell, Séverine Metzger, Thomas Duhen, Olivier Trédan, Christophe Caux, and Christine Ménétrier-Caux

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Impact of Variant Histology on Oncological Outcomes in Upper Tract Urothelial Carcinoma: Results From the ROBUUST Collaborative Group., Antoin Douglawi, Alireza Ghoreifi, Umberto Carbonara, Wesley Yip, Robert G Uzzo, Vitaly Margulis, Matteo Ferro, Ottavio De Cobelli, Zhenjie Wu, Giuseppe Simone, Riccardo Mastroianni, Koon H Rha, Daniel D Eun, Adam C Reese, James R Porter, Ithaar Derweesh, Reza Mehrazin, Giuseppe Rosiello, Riccardo Tellini, Marcus Jamil, Alexander Kenigsberg, Jason M Farrow, William P Schrock, Giovanni Cacciamani, Abhishek Srivastava, Amit S Bhattu, Alexandre Mottrie, Mark L Gonzalgo, Chandru P Sundaram, Firas Abdollah, Andrea Minervini, Riccardo Autorino, and Hooman Djaladat

CD4 and CD8 T cell responses in human solid tumors. Duhen T. Wilske Seminar- Benaroya Research Institute 2023 December 7; Seattle, WA., T Duhen

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Pembrolizumab in Patients With Tumors With High Tumor Mutational Burden: Results From the Targeted Agent and Profiling Utilization Registry Study., Herbert L Duvivier, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Eugene R Ahn, Tareq Al Baghdadi, Ajjai S Alva, Stephanie A Dublis, Timothy L Cannon, Carmen J Calfa, Rui Li, Deepti Behl, Vi K Chiu, Philip J Gold, Alissa S Marr, Kathryn F Mileham, Steven Francis Powell, Jordi Rodon, Ramya Thota, Gina N Grantham, Abigail Gregory, Dominique C Hinshaw, Susan Halabi, and Richard L Schilsky

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Results from a phase 1a/1b study of botensilimab (BOT), a novel innate/adaptive immune activator, plus balstilimab (BAL; anti-PD-1 antibody) in metastatic heavily pretreated microsatellite stable colorectal cancer (MSS CRC)., Anthony B. El-Khoueiry, K A Margolin, Rachel E Sanborn, and See all authors in comments

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Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial., Espen B Ellingsen, Steven O'Day, Artur Mezheyeuski, Agnieszka Gromadka, Trevor Clancy, Timothy S Kristedja, Mohammed Milhem, and Yousef Zakharia

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Construction and validation of a gene expression classifier to predict immunotherapy response in primary triple-negative breast cancer., Miquel Ensenyat-Mendez, Javier I J Orozco, Pere Llinàs-Arias, Sandra Íñiguez-Muñoz, Jennifer L Baker, Matthew P Salomon, Mercè Martí, Maggie L DiNome, Javier Cortés, and Diego M Marzese

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Pembrolizumab plus Chemotherapy in Advanced Endometrial Cancer., Ramez N Eskander, Michael W Sill, Lindsey Beffa, Richard G Moore, Joanie M Hope, Fernanda Musa, Robert Mannel, Mark S Shahin, Guilherme H Cantuaria, Eugenia Girda, Cara Mathews, Juraj Kavecansky, Charles A Leath, Lilian T Gien, Emily M Hinchcliff, Shashikant B Lele, Lisa M Landrum, Floor Backes, Roisin E O'Cearbhaill, Tareq Al Baghdadi, Emily K Hill, Premal H Thaker, Veena S John, Stephen Welch, Amanda N Fader, Matthew A Powell, and Carol Aghajanian

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Regarding: "Predicting Regional Lymph Node Recurrence in the Modern Age of Tumor-Positive Sentinel Node Melanoma," by Faries, Mark et al., Richard Essner and Jennifer Keller

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Objective assessment of intraoperative skills for robot-assisted partial nephrectomy (RAPN)., Rui Farinha, Alberto Breda, James Porter, Alexandre Mottrie, Ben Van Cleynenbreugel, Jozef Vander Sloten, Angelo Mottaran, and Anthony G Gallagher

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National Cancer Institute Imaging Data Commons: Toward Transparency, Reproducibility, and Scalability in Imaging Artificial Intelligence., Andrey Fedorov, William J R Longabaugh, David Pot, David A Clunie, Steven D Pieper, David L Gibbs, Christopher Bridge, Markus D Herrmann, André Homeyer, Rob Lewis, Hugo J W L Aerts, Deepa Krishnaswamy, Vamsi Krishna Thiriveedhi, Cosmin Ciausu, Daniela P Schacherer, Dennis Bontempi, Todd Pihl, Ulrike Wagner, Keyvan Farahani, Erika Kim, and Ron Kikinis

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Overall survival with adjuvant atezolizumab after chemotherapy in resected stage II-IIIA non-small-cell lung cancer (IMpower010): a randomised, multicentre, open-label, phase III trial., E Felip, N Altorki, C Zhou, Eric Vallieres, A Martínez-Martí, A Rittmeyer, A Chella, M Reck, O Goloborodko, M Huang, R Belleli, V McNally, M K Srivastava, E Bennett, B J Gitlitz, and H A Wakelee

NKG2A expression on tumor reactive CD8 T cells is induced by IL-12, O Fesneau, J Huang, T Duhen, and See full list of authors in comments

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Multidimensional biomarker predicts disease control in response to immunotherapy in recurrent or metastatic head and neck squamous-cell carcinoma., Kevin C Flanagan, Jon Earls, Ian Schillebeeckx, Jeffrey Hiken, Rachel L Wellinghoff, Natalie A LaFranzo, Zachary S Bradley, Joey Babbitt, William H Westra, Raymond Hsu, Lincoln Nadauld, Howard Mcleod, Sean D Firth, Brittany Sharp, Josh Fuller, Vera Vavinskaya, Leisa Sutton, Ida Deichaite, Samuel D Bailey, Vlad C Sandulache, Matthew J Rendo, Orlan K Macdonald, Karim Welaya, James L Wade, Andrew W Pippas, Jennifer Slim, Bruce Bank, Steven J Saccaro, Xingwei Sui, Adil Akhtar, Savitha Balaraman, Steven E Kossman, Scott A Sonnier, Todd D Shenkenberg, Warren L Alexander, Katherine A Price, Charles L Bane, Jessica Ley, David N Messina, Jarret I Glasscock, Ezra E W Cohen, Douglas R Adkins, and Eric J Duncavage

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Abstract 4876: A systems pharmacology approach to discover synergistic targeted therapy combinations, Cameron T. Flower, Chunmei Liu, James R Heath, Wei Wei, and Forest M. White

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American Society for Gastrointestinal Endoscopy guideline on endoscopic submucosal dissection for the management of early esophageal and gastric cancers: summary and recommendations., Nauzer Forbes, Sherif E Elhanafi, Mohammad A Al-Haddad, Nirav C Thosani, Peter V Draganov, Mohamed O Othman, Eugene P Ceppa, Vivek Kaul, Michael M Feely, Ilyas Sahin, James L Buxbaum, Audrey H Calderwood, Jean M Chalhoub, Nayantara Coelho-Prabhu, Madhav Desai, Larissa L Fujii-Lau, Divyanshoo R Kohli, Richard S Kwon, Jorge D Machicado, Neil B Marya, Swati Pawa, Wenly Ruan, Sunil G Sheth, Andrew C Storm, Nikhil R Thiruvengadam, and Bashar J Qumseya

Applying Proteogenomics to Identify Cancer’s Non-Canonical Alternative Neoantigens and the Development of Immunotherapies Targeting Those Antigens, B Fox

Applying Proteogenomics to Identify Cancer’s Non-Canonical Alternative Neoantigens and the Development of Immunotherapies Targeting Those Antigens and Other SLiPs, B Fox

Immune Interception of Pre-Malignancy, B Fox

Cancer Vaccines, Bernard Fox

Cancer Vaccine Strategies, Bernard Fox

Cellular Therapy, Bernard Fox

Developing Combination Immunotherapy that Includes Cancer Vaccines, Bernard Fox

Developing Combination Immunotherapy with Agents Lacking Strong Single Agent Therapeutic Activity: Cancer Vaccines - a Case in Point, Bernard Fox

Developing Combination Immunotherapy with Cancer Vaccines, Bernard Fox

Developing Combination Immunotherapy with Cancer Vaccines, Bernard Fox

Immunotherapy of Cancer, Bernard Fox

Peptidomics: identifying cancer’s dark matter and canonical targets- a possible strategy for universal cancer vaccines, Bernard Fox

Peptidomics: Unraveling the Universe of Peptides Cancer Cells Display. Fox B. European Society for Medical Oncology (ESMO) Immuno-Oncology Meeting; 2023 December 7; Geneva, Switzerland., Bernard Fox

Principles of Tumor Immunity. Fox B. ESMO-SITC Primer, ESMO Immuno-Oncology Meeting; 2023 December 6; Geneva, Switzerland., Bernard Fox

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Cancer's Dark Matter: Lighting the Abyss Unveils Universe of New Therapies., Bernard A Fox, Walter J Urba, Shawn M Jensen, David B Page, Brendan D Curti, Rachel E Sanborn, and Rom S Leidner

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Abstract 901: Monitoring of Neoantigens and Adoptively Transferred Personalized NeoTCR T Cell Populations in the Tumor and PBMCs of Patients with Solid Tumors, Susan Foy, Cliff Wang, Benjamin Yuen, Sara Said, Boi Quach, Jonathan Hoover, Saparya Nayak, Theresa Hunter, Zheng Pan, Chad Smith, Tyler Borrman, Eric Stawiski, Alphonsus H.C. Ng, Yue Lu, James R Heath, and Stefanie Mandl

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Inhibition of Microsomal Prostaglandin E2 Synthase Reduces Collagen Deposition in Melanoma Tumors and May Improve Immunotherapy Efficacy by Reducing T-cell Exhaustion., Yasunari Fukuda, Sun-Hee Kim, Matias A Bustos, Sung-Nam Cho, Jason Roszik, Jared K Burks, Hong Kim, Dave S B Hoon, Elizabeth A Grimm, and Suhendan Ekmekcioglu

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Spatial profiling of cancer-associated fibroblasts of sporadic early onset colon cancer microenvironment., Satoru Furuhashi, Matias A Bustos, Shodai Mizuno, Suyeon Ryu, Yalda Naeini, Anton J Bilchik, and Dave SB Hoon

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Pertuzumab Plus Trastuzumab in Patients With Lung Cancer With ERBB2 Mutation or Amplification: Results From the Targeted Agent and Profiling Utilization Registry Study, Apar K Ganti, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Elie G Dib, Herbert L Duvivier, Eugene R Ahn, Deepti Behl, Hossein Borghaei, Ani S Balmanoukian, Anu Gaba, Rui Li, Kwabena Osei-Boateng, Ramya Thota, Gina N Grantham, Abigail Gregory, Susan Halabi, and Richard L Schilsky

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Robot-assisted retroperitoneal lymph node dissection: a systematic review of perioperative outcomes., Harshit Garg, Ahmed M Mansour, Sarah P Psutka, Simon P Kim, James Porter, Christine S Gaspard, Furkan Dursun, Deepak K Pruthi, Hanzhang Wang, and Dharam Kaushik

Phase 1/2 study of PRO1160, a CD70-directed antibody-drug conjugate, in patients with advanced solid tumors and hematologic malignancies, B Garmezy, Brendan Curti, and See full list of authors in comments

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Feasibility of intraoperative injection of radioactive tracer and blue dye for sentinel lymph node biopsy in vulvar cancer., Alison A Garrett, Jason Ricciuti, Susan M Lang, Mary E Burriss, Margaret Flanigan, Emily O'Brien, Casey Hay, Jamie Lesnock, Jessica L Berger, and Sarah E Taylor

13. Long-term efficacy, safety and predictors of response to amivantamab among patients with post-platinum EGFR exon 20 insert (Ex20ins)-mutated advanced non-small cell lung cancer (aNSCLC) — CHRYSALIS (NCT02609776), P Garrido, Rachel E Sanborn, and See full list of authors in comments

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Timing and duration of bevacizumab treatment and survival in patients with recurrent ovarian, fallopian tube, and peritoneal cancer: a multi-institution study., Talayeh S Ghezelayagh, Emily S Wu, Emma L Barber, Minh D Dao, Emese Zsiros, Renata R Urban, Heidi J Gray, Barbara A Goff, Chirag A Shah, Nikki L Neubauer, James Y Dai, Janos L Tanyi, and John B Liao

Precise tumor & patient selection for CDR404: A bispecific & bivalent MAGE-A4 T cell engager, G Giacomazzi, Rom Leidner, and See full list of authors in comments

The presence of targetable mutations in metastatic non-small cell lung cancer patients with malignant pleural disease is not associated with improved survival The American Thoracic Society Washington, DC, CR Gilbert, CL Wilshire, and See all authors in comments

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Mammogram perceptions, communication, and gaps in care among individuals with non-English language preference in Oregon and Washington states., Monique Gill, Hannah Cohen-Cline, Megan Holtorf, and Keri Vartanian

Risk factors for venous thromboembolism (VTE) among patients with EGFR-mutated advanced non-small cell lung cancer (NSCLC) receiving amivantamab plus lazertinib versus either agent alone, N Girard, Rachel Sanborn, and See all authors in comments

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Characterization of Lymph Node Tumor Burden in Node-Positive Prostate Cancer Patients after Robotic-Assisted Radical Prostatectomy with Extended Pelvic Lymph Node Dissection., Josh Gottlieb, Shu-Ching Chang, Jane Choe, Gary Grunkemeier, Douglas Hanes, David L Krasne, Dave S B Hoon, and Timothy G Wilson

Characterization of immune cell trafficking to the draining lymph node following tumor radiation therapy using fluorescence tracking, MJ Gough

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Predictors of Intraoperative Difficulty and Postoperative Examination Abnormalities in 164 Orbital Operations., Akshay Govind, Shaban Demirel, Kristin Lee, Melissa Amundson, Richard Bryan Bell, and Eric Dierks

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Pap smear recommendations in older women, does the data support stopping?, Emma Grabinski and Rebecca Dunsmoor-Su

“Impact of Her2 Low on Survival in Patients Treated with Standard Therapies in Advanced Breast Cancer”, SL Graff, Bansal Rani, Adeyelu Tolulope, Elliott Andrew, Walker Phillip, MA Bustos, Rodriguez Estelamari, and See full list of authors in comments

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Newly Approved and Emerging Agents in HER2-Positive Metastatic Breast Cancer., Stephanie L Graff, Fengting Yan, and Yara Abdou

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Extraordinary clinical response to ibrutinib in low-grade ovarian cancer guided by organoid drug testing., Heidi J Gray, Payel Chatterjee, Rachele Rosati, Lauren R Appleyard, Grace J Durenberger, Robert L Diaz, Hallie A Swan, Danielle Peretti, Maddy Pollastro, Trevor Ainge, Katannya Kapeli, Shalini Pereira, Astrid L Margossian, Kalyan Banda, Barbara A Goff, Elizabeth M Swisher, Brady Bernard, Christopher J Kemp, and Carla Grandori

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Evidence-based procedures to improve the reliability of circulating miRNA biomarker assays., Sarah R Greytak, Kelly B Engel, Dave S B Hoon, Kevin M Elias, Christina M Lockwood, Ping Guan, and Helen M Moore

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HN-CLEAR: Head and Neck Consensus Language for Ease and Reproducibility, a Multidisciplinary Consensus Mechanism for Head and Neck Pathology., Ruta Gupta, Munita Bal, Justin A Bishop, Keith D Hunter, Kelly Magliocca, Raja R Seethala, Lester D R Thompson, Ilan Weinreb, Peter Angelos, Beth Beadle, R Bryan Bell, Jonathan R Clark, Robert Ferris, Shao Hui Huang, D Neil Hayes, Rahul Ladwa, Jean Yang, Nicole A Cipriani, Brenda L Nelson, Peter M Sadow, and James S Lewis

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A large-scale targeted proteomics of serum and tissue shows the utility of classifying high grade and low grade meningioma tumors., Ankit Halder, Deeptarup Biswas, Aparna Chauhan, Adrita Saha, Shreeman Auromahima, Deeksha Yadav, Mehar Un Nissa, Gayatri Iyer, Shashwati Parihari, Gautam Sharma, Sridhar Epari, Prakash Shetty, Aliasgar Moiyadi, Graham Roy Ball, and Sanjeeva Srivastava

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Monitoring and Surveillance of Patients with Gastroenteropancreatic Neuroendocrine Tumors Undergoing Radioligand Therapy., Thorvardur R Halfdanarson, Nadine Mallak, Scott Paulson, Chandrikha Chandrasekharan, Mona Natwa, Ayse Tuba Kendi, and Hagen F Kennecke

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Sentinel lymphatic mapping for gynecologic malignancies., Anjali Y Hari and Krishnansu S Tewari

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Three-Year Overall Survival with Tebentafusp in Metastatic Uveal Melanoma., Jessica C Hassel, Sophie Piperno-Neumann, Piotr Rutkowski, Jean-Francois Baurain, Max Schlaak, Marcus O Butler, Ryan J Sullivan, Reinhard Dummer, John M Kirkwood, Marlana Orloff, Joseph J Sacco, Sebastian Ochsenreither, Anthony M Joshua, Lauris Gastaud, Brendan Curti, Josep M Piulats, April K S Salama, Alexander N Shoushtari, Lev Demidov, Mohammed Milhem, Bartosz Chmielowski, Kevin B Kim, Richard D Carvajal, Omid Hamid, Laura Collins, Koustubh Ranade, Chris Holland, Constance Pfeiffer, and Paul Nathan

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An NKG2A biased immune response confers protection for infection, autoimmune disease, and cancer., James R Heath, Daniel Chen, Jingyi Xie, Jongchan Choi, Rachel H Ng, Rongyu Zhang, Sarah Li, Rick Edmark, Hong Zheng, Benjamin Solomon, Katie Campbell, Egmidio Medina, Antoni Ribas, Purvesh Khatri, Lewis Lanier, Philip Mease, Jason D Goldman, and Yapeng Su

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Randomized phase II trial of farletuzumab plus chemotherapy versus placebo plus chemotherapy in low CA-125 platinum-sensitive ovarian cancer., Thomas J Herzog, Sandro Pignata, Sharad A Ghamande, Maria-Jesús Rubio, Keiichi Fujiwara, Christof Vulsteke, Deborah K Armstrong, Jalid Sehouli, Robert L Coleman, Hani Gabra, Giovanni Scambia, Bradley J Monk, José A Arranz, Kimio Ushijima, Rabbie Hanna, Claudio Zamagni, Robert M Wenham, Antionio González-Martín, Brian Slomovitz, Yan Jia, Lisa Ramsay, Krishnansu S Tewari, Susan C Weil, and Ignace B Vergote

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T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants., Daniel Hirschhorn, Sadna Budhu, Lukas Kraehenbuehl, Mathieu Gigoux, David Schröder, Andrew Chow, Jacob M Ricca, Billel Gasmi, Olivier De Henau, Levi Mark B Mangarin, Yanyun Li, Linda Hamadene, Anne-Laure Flamar, Hyejin Choi, Czrina A Cortez, Cailian Liu, Aliya Holland, Sara Schad, Isabell Schulze, Allison Betof Warner, Travis J Hollmann, Arshi Arora, Katherine S Panageas, Gabrielle A Rizzuto, Rebekka Duhen, Andrew D Weinberg, Christine N Spencer, David Ng, Xue-Yan He, Jean Albrengues, David Redmond, Mikala Egeblad, Jedd D Wolchok, and Taha Merghoub

T cell immunotherapies recruit and activate neutrophils to eliminate tumor antigen escape variants, D Hirschorn, AD Weinberg, and See full list of authors in comments

Characterization of tumor specific CD8+ T cell responses in patients with recurrent/metastatic HPV16-positive head and neck cancer receiving HB-200 monotherapy as second or later line treatment in a phase 1 study, AL Ho, Rom Leidner, and See full list of authors in comments

Monitoring 1q21.3 amplification in circulating tumor DNA from metastatic melanoma patients receiving immune checkpoint inhibitor therapies, DSB Hoon, SY Lin, Y Kobayashi, X Zhang, Q Yu, S O’Day, and MA Bustos

“UBQLN4 triggers MRE11a and STING proteasomal degradation during cisplatin-induced DNA damage response in solid tumors, DSB Hoon, Y Shiloh, T Murakami, Y Kobayashi, R Jachimowicz, and MA Bustos

Mouse Models for Sarcoma Research: NEAT1 Promotes Sarcoma Metastasis, J Huang

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Organotypic Models for Functional Drug Testing of Human Cancers., Yu Ling Huang, Lindsay K Dickerson, Heidi Kenerson, Xiuyun Jiang, Venu Pillarisetty, Qiang Tian, Leroy Hood, Taranjit S Gujral, and Raymond S Yeung

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Organotypic Models for Functional Drug Testing of Human Cancers, Yu Ling Huang, Lindsay K. Dickerson, Heidi Kenerson, Xiuyun Jiang, Venu Pillarisetty, Qiang Tian, Leroy Hood, Taranjit S. Gujral, and Raymond S. Yeung

Pan-cancer associations of B7-H3 (CD276) transcriptioinal expression across human malignancies. ASCO, Abst:2624, 6/2023., J Hwang, Dave Hoon, and See full list of authors in comments

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Multi-omic profiling reveals discrepant immunogenic properties and a unique tumor microenvironment among melanoma brain metastases., Gino K In, Jennifer R Ribeiro, Jun Yin, Joanne Xiu, Matias A Bustos, Fumito Ito, Frances Chow, Gabriel Zada, Lindsay Hwang, April K S Salama, Soo J Park, Justin C Moser, Sourat Darabi, Evidio Domingo-Musibay, Maria L Ascierto, Kim Margolin, Jose Lutzky, Geoffrey T Gibney, Michael B Atkins, Benjamin Izar, Dave Hoon, and Ari M VanderWalde

Detection of KRAS G12D/G12V neoepitopes expressed by cancer cell lines using LC-MS/MS, N Iwamoto, Will Redmond, Brian Piening, Bernard Fox, Eric Tran, and See full list of authors in comments

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The Vicious Cycle of Melanoma-Microglia Crosstalk: Inter-Melanoma Variations in the Brain-Metastasis-Promoting IL-6/JAK/STAT3 Signaling Pathway., Sivan Izraely, Shlomit Ben-Menachem, Sapir Malka, Orit Sagi-Assif, Matias A Bustos, Orit Adir, Tsipi Meshel, Maharrish Chelladurai, Suyeon Ryu, Romela Irene Ramos, Metsada Pasmanik-Chor, Dave S B Hoon, and Isaac P Witz