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Submissions from 2022

Comprehensive Spatial Phenotyping: Mapping the Tumor Microenvironment at Scale, Bernard Fox

Immune Activating and Cancer Vaccine Technology, Bernard Fox

Overview of Immunotherapy and Challenges for Immuno-Oncology, Bernard Fox

Progress in Cellular Immunotherapy - It is not Just Mutations: A Vision into Combinations to Expect in 2023 and Beyond, Bernard Fox

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Non-viral precision T cell receptor replacement for personalized cell therapy., Susan P Foy, Kyle Jacoby, Daniela A Bota, Theresa Hunter, Zheng Pan, Eric Stawiski, Yan Ma, William Lu, Songming Peng, Clifford L Wang, Benjamin Yuen, Olivier Dalmas, Katharine Heeringa, Barbara Sennino, Andy Conroy, Michael T Bethune, Ines Mende, William White, Monica Kukreja, Swetha Gunturu, Emily Humphrey, Adeel Hussaini, Duo An, Adam J Litterman, Boi Bryant Quach, Alphonsus H C Ng, Yue Lu, Chad Smith, Katie M Campbell, Daniel Anaya, Lindsey Skrdlant, Eva Yi-Hsuan Huang, Ventura Mendoza, Jyoti Mathur, Luke Dengler, Bhamini Purandare, Robert Moot, Michael C Yi, Roel Funke, Alison Sibley, Todd Stallings-Schmitt, David Y Oh, Bartosz Chmielowski, Mehrdad Abedi, Yuan Yuan, Jeffrey A Sosman, Sylvia M Lee, Adam J Schoenfeld, David Baltimore, James R Heath, Alex Franzusoff, Antoni Ribas, Arati V Rao, and Stefanie J Mandl

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Correction: Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma., Yasunari Fukuda, Matias A Bustos, Sung-Nam Cho, Jason Roszik, Suyeon Ryu, Victor M Lopez, Jared K Burks, Jeffrey E Lee, Elizabeth A Grimm, Dave S B Hoon, and Suhendan Ekmekcioglu

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Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma., Yasunari Fukuda, Matias A Bustos, Sung-Nam Cho, Jason Roszik, Suyeon Ryu, Victor M Renteria-Lopez, Jared K Burks, Jeffrey E Lee, Elizabeth A Grimm, Dave Hoon, and Suhendan Ekmekcioglu

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Recommended phase 2 dose (RP2D) of HB-200 arenavirus-based cancer immunotherapies in patients with HPV16+ cancers., Siqing Fu, Rom Leidner, and Matthew H Taylor

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Differentiation of Subjective Cognitive Decline, Mild Cognitive Impairment, and Dementia Using qEEG/ERP-Based Cognitive Testing and Volumetric MRI in an Outpatient Specialty Memory Clinic., Aarthi S Ganapathi, Ryan M Glatt, Tess H Bookheimer, Emily S Popa, Morgan L Ingemanson, Casey J Richards, John F Hodes, Kyron P Pierce, Colby B Slyapich, Fatima Iqbal, Jenna Mattinson, Melanie G Lampa, Jaya M Gill, Ynez M Tongson, Claudia L Wong, Mihae Kim, Verna R Porter, Santosh Kesari, Somayeh Meysami, Karen J Miller, Jennifer E Bramen, David A Merrill, and Prabha Siddarth

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Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy., Julio Garcia-Aguilar, Sujata Patil, Marc J Gollub, Jin K Kim, Jonathan B Yuval, Hannah M Thompson, Floris S Verheij, Dana M Omer, Meghan Lee, Richard F Dunne, Jorge Marcet, Peter Cataldo, Blase Polite, Daniel O Herzig, David Liska, Samuel Oommen, Charles M Friel, Charles Ternent, Andrew L Coveler, Steven Hunt, Anita Gregory, Madhulika G Varma, Brian L Bello, Joseph C Carmichael, John Krauss, Ana Gleisner, Philip B Paty, Martin R Weiser, Garrett M Nash, Emmanouil Pappou, José G Guillem, Larissa Temple, Iris H Wei, Maria Widmar, Sabrina Lin, Neil H Segal, Andrea Cercek, Rona Yaeger, J Joshua Smith, Karyn A Goodman, Abraham J Wu, and Leonard B Saltz

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Management of the undescended testis in children: An American pediatric surgical association outcomes and evidence based practice committee systematic review., Robert L Gates, Julia Shelton, Karen A Diefenbach, Meghan Arnold, Shawn D St Peter, Elizabeth J Renaud, Mark B Slidell, Stig Sømme, Patricia Valusek, Gustavo A Villalona, Jarod P McAteer, Alana L Beres, Joanne Baerg, Rebecca M Rentea, Lorraine Kelley-Quon, Akemi L Kawaguchi, Yue-Yung Hu, Doug Miniati, Robert Ricca, and Robert Baird

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Label-free plasma proteomics for the identification of the putative biomarkers of oral squamous cell carcinoma., Shashyendra Singh Gautam, Raghwendra Pratap Singh, Kajal Karsauliya, Ashish Kumar Sonker, Panga Jaipal Reddy, Divya Mehrotra, Sameer Gupta, Sudhir Singh, Rashmi Kumar, and Sheelendra Pratap Singh

A Phase 1 Study of TAK-676, a Novel STING Agonist, Plus Pembrolizumab Following Radiation Therapy in Patients with Advanced Non–Small-Cell Lung Cancer (NSCLC), Triple-Negative Breast Cancer (TNBC), or Squamous-Cell Carcinoma of the Head and Neck (SCCHN), NK Gerber, DB Page, and See all authors in comments

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A phase 2 study of an off-the-shelf, multi-neoantigen vector (ADXS-503) in patients with metastatic non–small cell lung cancer either progressing on prior pembrolizumab or in the first-line setting., Gregory James Gerstner, Rachel E Sanborn, and See full list of authors in comments

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Verification of a Novel Minimally Invasive Device for the Isolation of Rare Circulating Tumor Cells (CTC) in Cancer Patients' Blood., Paul Friedrich Geus, Felix Hehnen, Sophia Krakowski, Klaus Lücke, Dave Hoon, Nikolaj Frost, Ulrich Kertzscher, and Gabi Wendt

Safety Analyses of NRG BR004: A Randomized, Double-blind, Phase III Trial of Taxane/Trastuzumab/Pertuzumab with Atezolizumab or Placebo in First-line HER2-Postive Metastatic Breast Cancer (MBC), CE Geyer and DB Page

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Robotic post-chemotherapy retroperitoneal lymph node dissection for testicular cancer: A multicenter collaborative study., Alireza Ghoreifi, Anirban P Mitra, George McClintock, Fady Baky, Zachary McDowell, Etienne Lavallée, Ragheed Saoud, Jie Cai, Inderbir S Gill, John Sfakianos, James R Porter, Aditya Bagrodia, Nariman Ahmadi, Scott Eggener, John F Ward, and Hooman Djaladat

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Management of recurrent transudative pleural effusions: can we REDUCE unnecessary interventions?, Christopher R Gilbert and José M Porcel

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Safety of Nivolumab Added to Chemoradiation Therapy Platforms for Intermediate and High-Risk Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: Radiation Therapy Oncology Group Foundation 3504., Maura L Gillison, Robert L Ferris, Jonathan Harris, A Dimitrios Colevas, Loren K Mell, Christina Kong, Richard C Jordan, Kevin L Moore, Minh-Tam Truong, Claudia Kirsch, Arnab Chakravarti, Dukagjin M Blakaj, David A Clump, James P Ohr, John F Deeken, Michael F Gensheimer, Nabil F Saba, Jennifer A Dorth, David I Rosenthal, Rom S Leidner, Randall J Kimple, Mitchell Machtay, Walter J Curran, Pedro Torres-Saavedra, and Quynh Thu Le

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Malignant Myopericytoma of the Right Foot: A Case Report, Ryan Glendenning

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A phase 1b, multicenter, dose-escalation study of subasumstat (TAK-981) in combination with pembrolizumab in patients (pts) with advanced solid tumors., Sanjay Goel, Rachel E Sanborn, and See full list of authors in comments

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Differences in the management of thyroid nodules in children and adolescents as compared to adults., Melanie Goldfarb and Catherine Dinauer

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Survivorship, Quality of Life, and Transition to Adult Care for Pediatric and Adolescent Thyroid Cancer Survivors., Melanie Goldfarb and Aime T Franco

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COVID-19 and Cancer: Special Considerations for Patients Receiving Immunotherapy and Immunosuppressive Cancer Therapies., Jason D Goldman, Michael A Gonzalez, Maria Madeleine Rüthrich, Elad Sharon, and Marie von Lilienfeld-Toal

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Safety and tolerability of MEDI0562, an OX40 agonist monoclonal antibody, in combination with durvalumab or tremelimumab in adult patients with advanced solid tumors., Jonathan W Goldman, Sarina A Piha-Paul, Brendan Curti, Katrina S Pedersen, Todd M Bauer, Stefanie L Groenland, Richard D Carvajal, Vaishali Chhaya, Gray Kirby, Kelly McGlinchey, Scott A Hammond, Katie L Streicher, Danielle Townsley, Young Kwang Chae, Jens Voortman, Aurelien Marabelle, and John Powderly

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Safety of Tumor Treating Fields (TTFields) therapy in pediatric patients with malignant brain tumors: Post-marketing surveillance data., Stewart Goldman, Ashley Margol, Eugene I Hwang, Kazuhiro Tanaka, Bogdana Suchorska, John R Crawford, and Santosh Kesari

The Development and Dynamics of Pre-existing immunity in tumors, Michael Gough

Fluorescence tagging to monitor CD8 T cell recirculation from the tumor to the tumor-draining lymph node: the impact of focal radiation therapy on recirculation, Michael J. Gough

Tumor resident memory CD8 T cell formation and concomitant tumor immunity is CD40L dependent and CD4 independent, Michael J. Gough

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The paradox of radiation and T cells in tumors., Michael J. Gough and Marka R Crittenden

Tumor resident memory CD8 T cell formation and concomitant tumor immunity is CD40L dependent and CD4 independent., Michael J. Gough, Thomas Duhen, Marka R Crittenden, and See all authors in comments

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Primary Care Physicians and Patients Prefer Colonoscopy for Colorectal Cancer Screening., Jessica M Gowing, Beth-Ann Shanker, Tendai K Thomas, and Robert K Cleary

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Pembrolizumab plus dinaciclib in patients with hematologic malignancies: the phase 1b KEYNOTE-155 study., Gareth P Gregory, Shaji Kumar, Ding Wang, Daruka Mahadevan, Patricia Walker, Nina Wagner-Johnston, Carolina Escobar, Rajat Bannerji, Divaya Bhutani, Julie Chang, Francisco J Hernandez-Ilizaliturri, Andreas Klein, John M Pagel, Witold Rybka, Andrew J Yee, Anne Mohrbacher, Mo Huang, Mohammed Farooqui, Patricia Marinello, and Hang Quach

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Impact of neurofibromatosis type 1 in an adult community population., Timothy A Gregory, Peter Simon B Molina, Gregory D Phillips, and John W Henson

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Prospective biomarker study in newly diagnosed glioblastoma: Cyto-C clinical trial., Corinne E Griguer, Claudia R Oliva, Christopher S Coffey, Merit E Cudkowicz, Robin A Conwit, Anna L Gudjonsdottir, Dixie J Ecklund, Janel K Fedler, Tina M Neill-Hudson, Louis B Nabors, Melanie Benge, James R Hackney, Marianne Chase, Timothy P Leonard, Toral Patel, Howard Colman, Macarena de la Fuente, Rekha Chaudhary, Karen Marder, Teri Kreisl, Nimish Mohile, Milan G Chheda, Katharine McNeill, Priya Kumthekar, Aclan Dogan, Jan Drappatz, Vinay Puduvalli, Agnes Kowalska, Jerome J Graber, Elizabeth Gerstner, Stephen Clark, Michael Salacz, and James Markert

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Outcomes of Lymph Node Dissection in Nephroureterectomy in the Treatment of Upper Tract Urothelial Carcinoma: Analysis of the ROBUUST Registry., Kevin Hakimi, Umberto Carbonara, Hooman Djaladat, Reza Mehrazin, Daniel Eun, Adam Reese, Mark L Gonzalgo, Vitaly Margulis, Robert G Uzzo, James R Porter, Chandru P Sundaram, Firas Abdollah, Alexandre Mottrie, Riccardo Tellini, Matteo Ferro, Arman Walia, Ava Saidian, Shady Soliman, Julia Yuan, Alessandro Veccia, Alireza Ghoreifi, Giovanni Cacciamani, Amit S Bhattu, Xiaosong Meng, Jason M Farrow, Marcus Jamil, Andrea Minervini, Koon H Rha, Zhenjie Wu, Giuseppe Simone, Riccardo Autorino, and Ithaar H Derweesh

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Clinical Course of Two Patients with COVID-19 Respiratory Failure After Administration of the Anticancer Small Molecule, RRx-001., Terese Catherine Hammond, Raymond C Lee, Bryan Oronsky, Tony R Reid, Scott Caroen, Tiffany M Juarez, Jaya Gill, Annie Heng, and Santosh Kesari

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Intratumoral Electroporation of Plasmid Encoded IL12 and Membrane-Anchored Anti-CD3 Increases Systemic Tumor Immunity., Mia Han, Bianca Nguyen, Jack Y Lee, Erica Browning, Jun Zhang, Anandaroop Mukhopadhyay, Ravindra Gujar, Jon Salazar, Reneta Hermiz, Lauren Svenson, Annah S Rolig, William L. Redmond, Alain P Algazi, Adil I Daud, David A Canton, and Christopher G Twitty

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Long-Term Outcomes of Patients on a Phase II Prospective Trial of Oligometastatic Hormone-Sensitive Prostate Cancer Treated with Androgen Deprivation and External Beam Radiation., Claire Hao, Colton Ladbury, Yung Lyou, Saro Manoukian, Christopher Ruel, Paul Frankel, Tanya Dorff, Jeffrey Wong, Sumanta Pal, Przemyslaw Twardowski, and Savita Dandapani

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Risk factors for cervical cancer among distinct populations in low-resource countries: feasibility of cervical cancer screen-and-treat program on ukerewe island of lake victoria, Tanzania., Anjali Y Hari, Megan Bernstein, Jamie Temko, Danielle E Brabender, Aricia Shen, and Krishnansu S Tewari

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Assessment of Regional Variability in COVID-19 Outcomes Among Patients With Cancer in the United States., Jessica E Hawley, Tianyi Sun, David D Chism, Narjust Duma, Julie C Fu, Na Tosha N Gatson, Sanjay Mishra, Ryan H Nguyen, Sonya A Reid, Oscar K Serrano, Sunny R K Singh, Neeta K Venepalli, Ziad Bakouny, Babar Bashir, Mehmet A Bilen, Paolo F Caimi, Toni K Choueiri, Scott J Dawsey, Leslie A Fecher, Daniel B Flora, Christopher R Friese, Michael J Glover, Cyndi J Gonzalez, Sharad Goyal, Thorvardur R Halfdanarson, Dawn L Hershman, Hina Khan, Chris Labaki, Mark A Lewis, Rana R McKay, Ian Messing, Nathan A Pennell, Matthew Puc, Deepak Ravindranathan, Terence D Rhodes, Andrea V Rivera, John Roller, Gary K Schwartz, Sumit A Shah, Justin A Shaya, Mitrianna Streckfuss, Michael A Thompson, Elizabeth M Wulff-Burchfield, Zhuoer Xie, Peter Paul Yu, Jeremy L Warner, Dimpy P Shah, Benjamin French, Clara Hwang, COVID-19 and Cancer Consortium (CCC19), and Hagen F Kennecke (COVID-19 and Cancer Consortium (CCC19))

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EDI and open access: How JACMP is the future of ethical publishing-A tale in two parts., Samantha G Hedrick and Susan L Richardson

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Radiofrequency ablation in the management of primary hepatic and biliary tumors., Richard Hendriquez, Tara Keihanian, Jatinder Goyal, Rtika R Abraham, Rajnish Mishra, and Mohit Girotra

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Pulmonary Open, Robotic, and Thoracoscopic Lobectomy study: Outcomes and risk factors of conversion during minimally invasive lobectomy., Luis J Herrera, Lana Y Schumacher, Matthew G Hartwig, Charles T Bakhos, Rishindra M Reddy, Eric Vallieres, and Michael S Kent

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5 Development of a vaccine to intercept oral cancer, Traci Hilton, Tarsem Moudgil, Richard Bryan Bell, and See all authors in comments

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731 A first-in-human trial of an integrin beta-6 targeted antibody-drug conjugate (ADC), SGN-B6A, in patients with advanced solid tumors: interim results of a phase 1 study (SGNB6A-001), Antoine Hollebecque, Rachel E Sanborn, and See full list of authors in comments

"Cisplatin-induced DNA damage triggers MRE11a proteasomal degradation mediated by UBQLN4 in solid tumors", DSB Hoon, Y Shiloh, T Murakami, Y Kobayashi, and MA Bustos

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Meta-analysis of randomized controlled trials on primary ambulatory thromboprophylaxis in patients with nonpancreatic gastrointestinal cancers receiving chemotherapy., Thura Win Htut, Kyaw Zin Thein, Donald Quick, and Thein Hlaing Oo

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Development and Validation of a Breast Cancer Polygenic Risk Score on the Basis of Genetic Ancestry Composition., Elisha Hughes, Susanne Wagner, Dmitry Pruss, Ryan Bernhisel, Braden Probst, Victor Abkevich, Timothy Simmons, Brooke Hullinger, Thaddeus Judkins, Eric Rosenthal, Benjamin Roa, Susan M Domchek, Charis Eng, Judy Garber, Monique Gary, Jennifer Klemp, Semanti Mukherjee, Kenneth Offit, Olufunmilayo I Olopade, Joseph Vijai, Jeffrey N Weitzel, Pat Whitworth, Lamis Yehia, Ora K Gordon, Holly Pederson, Allison Kurian, Thomas P Slavin, Alexander Gutin, and Jerry S Lanchbury

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Real-world evidence of a successful biosimilar adoption program., Sophia Z Humphreys

8 Universal LCMS-based assay platform, refmAb-Q nSMOL, for monitoring monoclonal antibody therapeutics using one reference antibody, Noriko Iawmoto, Yoshinobu Koguchi, Kotoko Yokoyama, Akinobu Hamada, Atsushi Yonezawa, Brian Piening, Eric Tran, Bernard Fox, William Redmond, and Takashi Shimada

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A Blood-Based Metabolite Panel for Distinguishing Ovarian Cancer from Benign Pelvic Masses., Ehsan Irajizad, Chae Y Han, Joseph Celestino, Ranran Wu, Eunice Murage, Rachelle Spencer, Jennifer B Dennison, Jody Vykoukal, James P Long, Kim Anh Do, Charles Drescher, Karen Lu, Zhen Lu, Robert C Bast, Sam Hanash, and Johannes F Fahrmann

Proteogenomic Characterization of Head and Neck Squamous Cell Cancer Immunopeptidomes to Detect Non Canonical Protein Targets for Cancer Immunotherapy., N Iwamoto, Richard Bryan Bell, Carlo Bifulco, Walter Urba, Rom Leidner, Brian D. Piening, Bernard A Fox, and See full author list in comments

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A rapid and universal liquid chromatograph-mass spectrometry-based platform, refmAb-Q nSMOL, for monitoring monoclonal antibody therapeutics., Noriko Iwamoto, Yoshinobu Koguchi, Kotoko Yokoyama, Akinobu Hamada, Atsushi Yonezawa, Brian D Piening, Eric Tran, Bernard A Fox, William L Redmond, and Takashi Shimada

Uncovering the dark immunopeptidome of head and neck squamous cell carcinoma (HNSCC): relevance for universal cancer vaccines, immunological monitoring and TIL therapy, Noriko Iwamoto, Takashi Shimada, Tarsem Moudgil, Ryan Meng, Tanisha Christie, Alexa Dowdell, Rom Leidner, Bryan Bell, William Redmond, Eric Tran, Hong-Ming Hu, Traci Hilton, Brian Piening, Yoshinobu Koguchi, and Bernard Fox

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RECOVERY AND SURVIVAL IN COVID-19 RESPIRATORY FAILURE‚ WHEN TREATED WITH AVIPTADIL, Dushyantha Jayaweera, David J Park, and See full list of authors in comments

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Agent-based computational modeling of glioblastoma predicts that stromal density is central to oncolytic virus efficacy., Adrianne L Jenner, Munisha Smalley, David Goldman, William F Goins, Charles Cobbs, Ralph B Puchalski, E Antonio Chiocca, Sean Lawler, Paul Macklin, Aaron Goldman, and Morgan Craig

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Interim results of an ongoing phase 1/2a study of HPN328, a tri-specific, half-life extended, DLL3-targeting, T-cell engager, in patients with small cell lung cancer and other neuroendocrine cancers., Melissa Lynne Johnson, Rachel E Sanborn, and See full list of authors in comments

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Tyrosine kinase-altered spindle cell neoplasms with EGFR internal tandem duplications., Erica Kao, Navin Pinto, Angela Trobaugh-Lotrario, Gail H Deutsch, Yu Wu, Wenjing Wang, Erin R Rudzinski, and Yajuan J Liu

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PCM1-JAK2 Fusion Tyrosine Kinase Gene-Related Neoplasia: A Systematic Review of the Clinical Literature., Henry G Kaplan, Ruyun Jin, Carlo Bifulco, James M Scanlan, and David R Corwin

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Trastuzumab therapy duration in HER2-positive de novo metastatic breast cancer: 1999-2018, Henry Kaplan, Judith A. Malmgren, Boya Guo, and Mary K. Atwood

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Ex vivo analysis of radiation effects on tumor infiltrating immune cells using tumor explants, Aanchal Preet Kaur, Gwen Kramer, Marka R. Crittenden, and Michael J. Gough

Ex vivo tumor explant analyses reveal suppression of tumor-infiltrating T cells, but not myeloid cells, post radiation treatment, AP Kaur, G Kramer, MR Crittenden, and MJ Gough

Multiomic Analyses Of Two Pig Kidney To Human Xenotransplants, B Keating, Brian Piening, M Mangiola, J Stern, W Zhang, A Griesemer, B Lonze, M Snyder, J Boeke, and R Montgomery

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Identification of the Collagen Types Essential for Mammalian Breast Acinar Structures., Chandler R Keller, Kelsey F Ruud, Steve R Martinez, and Weimin Li

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The SAGES MASTERS program presents: the 10 seminal articles for the Laparoscopic Right Colectomy Pathway., Deborah S Keller, Giovanni Dapri, Alexis L Grucela, George Melich, Ian M Paquette, Virginia O Shaffer, Konstantin Umanskiy, Angela H Kuhnen, Jeremy Lipman, Elisabeth C Mclemore, Mark Whiteford, and Patricia Sylla

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ASO Visual Abstract: Predicting Regional Lymph Node Recurrence in the Modern Age of Tumor-Positive Sentinel Node Melanoma: The Role of the First Postoperative Ultrasound., Jennifer Keller, Stacey Stern, Shu-Ching Chang, Rebecca Marcus, Jessica Weiss, Sean Nassoiy, Wade Christopher, Trevan Fischer, and Richard Essner

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Predicting Regional Lymph Node Recurrence in the Modern Age of Tumor-Positive Sentinel Node Melanoma: The Role of the First Postoperative Ultrasound., Jennifer Keller, Stacey Stern, Shu-Ching Chang, Rebecca Marcus, Jessica Weiss, Sean Nassoiy, Wade Christopher, Trevan Fischer, and Richard Essner

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Predicting Regional Lymph Node Recurrence in the Modern Age of Tumor-Positive Sentinel Node Melanoma: The Role of the First Postoperative Ultrasound., Jennifer Keller, Stacey Stern, Shu-Ching Chang, Rebecca Marcus, Jessica Weiss, Sean Nassoiy, Wade Christopher, Trevan Fischer, and Richard Essner

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Psychedelic-Assisted Therapy and Psychedelic Science: A Review and Perspective on Opportunities in Neurosurgery and Neuro-Oncology., Daniel F Kelly, Keith Heinzerling, Akanksha Sharma, Shanthi Gowrinathan, Karina Sergi, and Regin Jay Mallari

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Patterns of Practice and Improvements in Survival Among Patients With Stage 2/3 Rectal Cancer Treated With Trimodality Therapy., Hagen F Kennecke, Henry T Bahnson, Bruce Lin, Colin O'Rourke, Jennifer Kaplan, Huong Pham, Andrew Suen, and Vlad V Simianu

State of the Art Treatment of Rectal Cancer: Moving away from Trimodality Therapy, HF Kennecke

The NEO Trial Results: Organ Sparing Therapy in Rectal Cancer, HF Kennecke

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BETA PRIME: Phase I study of AdAPT-001 as monotherapy and combined with a checkpoint inhibitor in superficially accessible, treatment-refractory solid tumors., Santosh Kesari, Alberto Bessudo, Brian R Gastman, Anthony P Conley, Victoria M Villaflor, Lisle M Nabell, DeLisa Madere, Emma Chacon, Christina Spencer, Li Li, Christopher Larson, Tony Reid, Scott Caroen, Bryan Oronsky, Meaghan Stirn, Jeannie Williams, and Minal A Barve

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A preliminary safety assessment of vertebral augmentation with 32 P brachytherapy bone cement, Joyce H Keyak, Mando L Eijansantos, Katherine G Rosecrance, Daniel Wong, Sayeh Feizi, Aleen L Meldosian, Pranav Peddinti, Clifford M Les, Harry B Skinner, and Varun Sehgal

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Early Local Therapy for the Primary Site in De Novo Stage IV Breast Cancer: Results of a Randomized Clinical Trial (EA2108)., Seema A Khan, Fengmin Zhao, Lori J Goldstein, David Cella, Mark Basik, Mehra Golshan, Thomas B Julian, Barbara A Pockaj, Christine A Lee, Wajeeha Razaq, Joseph A Sparano, Gildy V Babiera, Irene A Dy, Sarika Jain, Paula Silverman, Carla S Fisher, Amye J Tevaarwerk, Lynne I Wagner, and George W Sledge

O006/#1066 Randomized trial of pelvic radiation with and without concurrent cisplatin in patients with a pelvic only recurrence of endometrial cancer, Ann Klopp, Christopher Darus, and See all authors in comments

“IFI16 promotes immune responses through IFN-γ pathway activation in metastatic cutaneous melanomas”, Y Kobayashi, MA Bustos, Q Yu, and DSB Hoon

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Genomic Amplification of, Yuta Kobayashi, Matias A Bustos, Yoshiaki Shoji, Ron D Jachimowicz, Yosef Shiloh, and Dave S B Hoon

Single-cell RNA-seq analysis of human tumor infiltrating T cells across multiple tumor types to discover potential targets for combination immunotherapy, Y Koguchi, T Christie, V Rajamanickam, N Simons, W Rosales, JK Kaufmann, B Bernard, and William Redmond

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A Novel Class of On-Treatment Cancer Immunotherapy Biomarker: Trough Levels of Antibody Therapeutics in Peripheral Blood., Yoshinobu Koguchi and William L Redmond

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Urine Cell-Free MicroRNAs in Localized Prostate Cancer Patients., Yoko Koh, Matias A Bustos, Jamie Moon, Rebecca Gross, Romela Irene Ramos, Suyeon Ryu, Jane Choe, Selena Y Lin, Warren M Allen, David L Krasne, Timothy G Wilson, and Dave Hoon

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Factors impacting genomic testing rates among epithelial ovarian cancer patients across a large community-based healthcare system (595), Nicole Kretzer, Christopher J. Darus, Nancy Biery, Roshanthi Weerasinghe, Hsin-Fang Li, Ann Vita, Shwetha Pindikuri, Amy Parrish, Charles Drescher, and Fernanda Musa

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Factors impacting genomic testing rates among epithelial ovarian cancer patients across a large community-based healthcare system, Nicole M. Kretzer, Christopher J. Darus, Nancy Biery, Roshanthi Weerasinghe, Grace Li, Ann Vita, Shwetha Pindikuri, Amy S. Parrish, Charles W Drescher, and Fernanda B. Musa

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Frequency of homologous recombination deficiency in a large community-based cohort of epithelial ovarian cancer cases, Nicole M. Kretzer, Fernanda B. Musa, Christopher Darus, Nancy Biery, Roshanthi Weerasinghe, Grace Li, Ann Vita, Shwetha Pindikuri, Amy S. Parrish, and Charles W Drescher

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Patterns of genomic testing for epithelial ovarian cancer across a large community-based health care network- a real world experience, Nicole M. Kretzer, Fernanda B. Musa, Christopher Darus, Nancy Biery, Roshanthi Weerasinghe, Grace Li, Ann Vita, Shwetha Pindikuri, Amy S. Parrish, and Charles W Drescher

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Frequency of homologous recombination deficiency in a large community-based cohort of epithelial ovarian cancer cases (597), Nicole Kretzer, Fernanda Musa, Christopher Darus, Nancy Biery, Roshanthi Weerasinghe, Hsin-Fang Li, Ann Vita, Shwetha Pindikuri, Amy Parrish, and Charles Drescher

Factors Impacting Genomic Testing Rates Among Epithelial Ovarian Cancer Patients ​Across a Large Community-Based Healthcare System, NM Kretzer, HF Li, and See all authors in comments

Frequency of Homologous Recombination Deficiency (HRD) in a Large Community Based Cohort of Epithelial Ovarian Cancer Cases (EOC), NM Kretzer, HF Li, and See all authors in comments

Patterns of Genomic Testing for Epithelial Ovarian Cancer (EOC) Across a Large Community-Based Health Care Network- A Real World Experience, NM Kretzer, HF Li, and See all authors in comments

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Everolimus with or without bevacizumab in advanced pNET: CALGB 80701 (Alliance)., Matthew H Kulke, Fang-Shu Ou, Donna Niedzwiecki, Lucas Huebner, Pamela Kunz, Hagen F Kennecke, Edward M Wolin, Jennifer A Chan, Eileen M O'Reilly, Jeffrey A Meyerhardt, and Alan Venook

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Sustained postoperative plasma elevations of plasminogen activator inhibitor-1 following minimally invasive colorectal cancer resection., H M C Shantha Kumara, Poppy Addison, Dasuni N Gamage, Erica Pettke, Abhinit Shah, Xiaohong Yan, Vesna Cekic, and Richard L Whelan

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The role of adjuvant chemotherapy in the management of acute promyelocytic leukemia differentiation syndrome., Dominic LaBella, Samuel Regan, Heiko Konig, Daniel N Egan, Neil Bailey, Raya Mawad, Morgan Gilbert, John M Pagel, and Jeffrey J Pu

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Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer., Julie E Lang, Andres Forero-Torres, Douglas Yee, Christina Yau, Denise Wolf, John Park, Barbara A Parker, A Jo Chien, Anne M Wallace, Rashmi Murthy, Kathy S Albain, Erin D Ellis, Heather Beckwith, Barbara B Haley, Anthony D Elias, Judy C Boughey, Rachel L Yung, Claudine Isaacs, Amy S Clark, Hyo S Han, Rita Nanda, Qamar J Khan, Kristen K Edmiston, Erica Stringer-Reasor, Elissa Price, Bonnie Joe, Minetta C Liu, Lamorna Brown-Swigart, Emanuel F Petricoin, Julia D Wulfkuhle, Meredith Buxton, Julia L Clennell, Ashish Sanil, Scott Berry, Smita M Asare, Amy Wilson, Gillian L Hirst, Ruby Singhrao, Adam L Asare, Jeffrey B Matthews, Michelle Melisko, Jane Perlmutter, Hope S Rugo, W Fraser Symmans, Laura J van 't Veer, Nola M Hylton, Angela M DeMichele, Donald A Berry, and Laura J Esserman

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Epidemiology of interstitial lung disease in patients with metastatic breast cancer at baseline and after treatment with HER2-directed therapy: a real-world data analysis., Jeanna Wallenta Law, Alicyn Campbell, Colin Weller, Colden Johanson, Ronda Broome, Elisabeth Piault, Monika Izano, Andrew Schrag, Mary Tran, Thomas D Brown, and Henry G Kaplan

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Real-World Treatment Patterns and Clinical Effectiveness of Palbociclib Plus an Aromatase Inhibitor as First-Line Therapy in Advanced/Metastatic Breast Cancer: Analysis from the US Syapse Learning Health Network., Jeanna Wallenta Law, Debanjali Mitra, Henry G Kaplan, Tamuno Alfred, Adam M Brufsky, Birol Emir, Haley McCracken, Xianchen Liu, Ronda G Broome, Chenan Zhang, Caroline DiCristo, and Connie Chen

The Multidisciplinary Management of NET Disease: Carcinoid Heart Disease, M E. Layoun

1473 Mechanism of action of bempegaldesleukin (BEMPEG) plus nivolumab (NIVO) in patients with unresectable or metastatic melanoma from the phase 3 randomized open-label PIVOT IO-001 clinical trial, Celeste Lebbe, Brendan Curti, Matthew Taylor, and See all authors in comments

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Cediranib in combination with olaparib in patients without a germline BRCA1/2 mutation and with recurrent platinum-resistant ovarian cancer: Phase IIb CONCERTO trial., Jung-Min Lee, Richard G Moore, Sharad Ghamande, Min Park, John P Diaz, Julia Chapman, James Kendrick, Brian M Slomovitz, Krishnansu S Tewari, Elizabeth S Lowe, Tsveta Milenkova, Sanjeev Kumar, Mike Dymond, Jessica Brown, and Joyce F Liu

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P2Y1 agonist HIC in combination with androgen receptor inhibitor abiraterone acetate impairs cell growth of prostate cancer., Hien Thi Thu Le, Akshaya Murugesan, Nuno R Candeias, Thiyagarajan Ramesh, Olli Yli-Harja, and Meenakshisundaram Kandhavelu