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Submissions from 2024

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The Journey to Improve the College of American Pathologists Cancer Biomarker Reporting Protocols., Brett Baskovich, Alexander Baras, Raja R Seethala, Patrick L Fitzgibbons, Frank Schneider, Brent T Harris, and Joseph Khoury

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Warm reactive autoantibodies detected by solid phase technology: Patient characteristics, laboratory features, and clinical significance., Douglas Blackall and J T Little

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Proteomic changes induced by longevity-promoting interventions in mice., Adam R Burns, Jack Wiedrick, Alicia Feryn, Michal Maes, Mukul K Midha, David H Baxter, Seamus R Morrone, Timothy J Prokop, Charu Kapil, Michael R Hoopmann, Ulrike Kusebauch, Eric W Deutsch, Noa Rappaport, Kengo Watanabe, Robert L Moritz, Richard A Miller, Jodi A Lapidus, and Eric S Orwoll

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Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity., Isabella C Glitza, Yongwoo David Seo, Christine N Spencer, Jennifer R Wortman, Elizabeth M Burton, Farah A Alayli, Christopher P Loo, Shikha Gautam, Ashish Damania, Julie Densmore, Justin Fairchild, Christopher R Cabanski, Matthew C Wong, Christine B Peterson, Brian Weiner, Nathan Hicks, John G Auniņš, Christopher McChalicher, Emily Walsh, Michael T Tetzlaff, Omid Hamid, Patrick A Ott, Genevieve M Boland, Ryan J Sullivan, Kenneth F Grossmann, Nadim J Ajami, Theresa LaVallee, Matthew R Henn, Hussein A Tawbi, and Jennifer A Wargo

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Principles of Analytic Validation of Immunohistochemical Assays: Guideline Update., Jeffrey D Goldsmith, Megan L Troxell, Sinchita Roy-Chowdhuri, Carol F Colasacco, Mary Elizabeth Edgerton, Patrick L Fitzgibbons, Regan Fulton, Thomas Haas, Patricia L Kandalaft, Tanja Kalicanin, Christina Lacchetti, Patti Loykasek, Nicole E Thomas, Paul E Swanson, and Andrew M Bellizzi

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The intersection of frailty and metabolism., Manish Mishra, Judy Wu, Alice E Kane, and Susan E Howlett

Submissions from 2023

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Rare presence of Charcot-Leyden crystals in acute myeloid leukemia., Sujan Badal, Mahnoosh Taheri, Peter Jiang, and Kirstine Oh

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A nontraditional presentation and treatment for emphysematous cystitis., Benjamin Becker, Asher George, and Ryan Owen

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Kidney Biopsy Utility: Patient and Clinician Perspectives from the Kidney Precision Medicine Project., Lauren Bernard, Ashley R Wang, Steven Menez, Joel M Henderson, Ashveena Dighe, Glenda V Roberts, Christine Stutzke, Katherine Tuttle, R Tyler Miller, and Kidney Precision Medicine Project

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Severe Hemolytic Disease of the Newborn due to Anti-Di, Douglas Blackall

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Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOVER initiative., Hector Bonilla, Michael J Peluso, Kathleen Rodgers, Judith A Aberg, Thomas F Patterson, Robert Tamburro, Lawrence Baizer, Jason D Goldman, Nadine Rouphael, Amelia Deitchman, Jeffrey Fine, Paul Fontelo, Arthur Y Kim, Gwendolyn Shaw, Jeran Stratford, Patricia Ceger, Maged M Costantine, Liza Fisher, Lisa O'Brien, Christine Maughan, John G Quigley, Vilma Gabbay, Sindhu Mohandas, David Williams, and Grace A McComsey

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OPTN required SARS-CoV-2 lower respiratory testing for lung donors: Striking the balance., Sarah E Booker, Courtney Jett, Cole Fox, Judith A Anesi, Gerald J Berry, Kelly E Dunn, Cynthia E Fisher, Jason D Goldman, Chak-Sum Ho, Michelle Kittleson, Dong Heun Lee, Deborah J Levine, Charles C Marboe, Gary Marklin, Carlos Martinez, Raymund R Razonable, Marty T Sellers, Sarah Taimur, Helen S Te, Anil J Trindade, R Patrick Wood, Ann E Woolley, Lorenzo Zaffiri, David K Klassen, Marian G Michaels, Stephanie M Pouch, Lara Danziger-Isakov, and Ricardo M La Hoz

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Proteomic changes induced by longevity-promoting interventions in mice., Adam R Burns, Jack Wiedrick, Alicia Feryn, Michal Maes, Mukul K Midha, David H Baxter, Seamus R Morrone, Timothy J Prokop, Charu Kapil, Michael R Hoopmann, Ulrike Kusebauch, Eric W Deutsch, Noa Rappaport, Kengo Watanabe, Robert L Moritz, Richard A Miller, Jodi A Lapidus, and Eric S Orwoll

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Consensus classification of pediatric hepatocellular tumors: A report from the Children's Hepatic tumors International Collaboration (CHIC)., Soo-Jin Cho, Sarangarajan Ranganathan, Rita Alaggio, Rudolf Maibach, Yukichi Tanaka, Takeshi Inoue, Ivo Leuschner, Ronald de Krijger, Christian Vokuhl, Mark Krailo, Marcio Malogolowkin, Rebecka Meyers, Piotr Czauderna, Eiso Hiyama, Marc Ansari, Bruce Morland, Angela Trobaugh-Lotrario, Allison F O'Neill, Arun Rangaswami, Beate Häberle, and Dolores López-Terrada

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Clinician-Performed Thyroid Fine Needle Aspiration With On-Site Review Improves Diagnostic Yield., Isabelle Chu, Oliver Bellevue, Joseph C Sniezek, and Nuria Perez-Reyes

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American Society for Gastrointestinal Endoscopy guideline on endoscopic submucosal dissection for the management of early esophageal and gastric cancers: summary and recommendations., Nauzer Forbes, Sherif E Elhanafi, Mohammad A Al-Haddad, Nirav C Thosani, Peter V Draganov, Mohamed O Othman, Eugene P Ceppa, Vivek Kaul, Michael M Feely, Ilyas Sahin, James L Buxbaum, Audrey H Calderwood, Jean M Chalhoub, Nayantara Coelho-Prabhu, Madhav Desai, Larissa L Fujii-Lau, Divyanshoo R Kohli, Richard S Kwon, Jorge D Machicado, Neil B Marya, Swati Pawa, Wenly Ruan, Sunil G Sheth, Andrew C Storm, Nikhil R Thiruvengadam, and Bashar J Qumseya

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Complex vulvar and vaginal disease in menopause., Ashley E Fuller and Rebecca Dunsmoor-Su

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Interoperable slide microscopy viewer and annotation tool for imaging data science and computational pathology., Chris Gorman, Davide Punzo, Igor Octaviano, Steven Pieper, William J R Longabaugh, David A Clunie, Ron Kikinis, Andrey Y Fedorov, and Markus D Herrmann

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Characterization of Lymph Node Tumor Burden in Node-Positive Prostate Cancer Patients after Robotic-Assisted Radical Prostatectomy with Extended Pelvic Lymph Node Dissection., Josh Gottlieb, Shu-Ching Chang, Jane Choe, Gary Grunkemeier, Douglas Hanes, David L Krasne, Dave S B Hoon, and Timothy G Wilson

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HN-CLEAR: Head and Neck Consensus Language for Ease and Reproducibility, a Multidisciplinary Consensus Mechanism for Head and Neck Pathology., Ruta Gupta, Munita Bal, Justin A Bishop, Keith D Hunter, Kelly Magliocca, Raja R Seethala, Lester D R Thompson, Ilan Weinreb, Peter Angelos, Beth Beadle, R Bryan Bell, Jonathan R Clark, Robert Ferris, Shao Hui Huang, D Neil Hayes, Rahul Ladwa, Jean Yang, Nicole A Cipriani, Brenda L Nelson, Peter M Sadow, and James S Lewis

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Bifidobacterium infantis supplementation versus placebo in early life to improve immunity in infants exposed to HIV: a protocol for a randomized trial., Anna-Ursula Happel, Lerato Rametse, Brandon Perumaul, Christian Diener, Sean M Gibbons, Donald D Nyangahu, Kirsten A Donald, Clive Gray, and Heather B Jaspan

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Uterine Inflammatory Myofibroblastic Tumors: Proposed Risk Stratification Model Using Integrated Clinicopathologic and Molecular Analysis., Nicholas R Ladwig, Gregory R Bean, Melike Pekmezci, John Boscardin, Nancy M Joseph, Nicole Therrien, Ankur R Sangoi, Brian D. Piening, Venkatesh Rajamanickam, Matthew Galvin, Brady Bernard, Charles Zaloudek, Joseph T Rabban, Karuna Garg, and Sarah E Umetsu

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Evaluation of solid-phase panreactivity with negative direct antiglobulin testing., J T Little and D P Blackall

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Organ-specific immunity: A tissue analysis framework for investigating local immune responses to SARS-CoV-2., Alphonsus H C Ng, Huiqian Hu, Kai Wang, Kelsey Scherler, Sarah E Warren, Daniel R Zollinger, Jill McKay-Fleisch, Kristina Sorg, Joseph M Beechem, Emily Ragaglia, J Matthew Lacy, Kelly D Smith, Desiree A Marshall, Michael M Bundesmann, Diego López de Castilla, David Corwin, Nicole Yarid, Beatrice S Knudsen, Yue Lu, Jason D Goldman, and James R Heath

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10 - Special Pathogens Team & Lab Activation, Providence - Special Pathogens Program

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11 - Providence Doffing Room, Providence - Special Pathogens Program

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1 - Special Pathogens Program, Providence - Special Pathogens Program

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2 - Special Pathogens Team, Providence - Special Pathogens Program

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3 - Donning Room, Providence - Special Pathogens Program

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4 - Special Pathogens Lab, Providence - Special Pathogens Program

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5 - Patient Room, Providence - Special Pathogens Program

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6 - Patient Room 2, Providence - Special Pathogens Program

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7 - Special Pathogens Unit Activation, Providence - Special Pathogens Program

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8 - Training & Exercise, Providence - Special Pathogens Program

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9 - Special Pathogens Research Network (SPRN) Poster, Providence - Special Pathogens Program

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June 2023: Region 10 Emerging Special Pathogen Treatment Center (RESPTC) at Providence Sacred Heart Medical Center & Children’s Hospital, Providence - Special Pathogens Program

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March 2023: Region 10 Emerging Special Pathogen Treatment Center (RESPTC) at Providence Sacred Heart Medical Center & Children’s Hospital, Providence - Special Pathogens Program

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September 2023: Region 10 Emerging Special Pathogen Treatment Center (RESPTC) at Providence Sacred Heart Medical Center & Children’s Hospital, Providence - Special Pathogens Program

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Multi-institutional Assessment of Pathologist Scoring HER2 Immunohistochemistry., Charles J Robbins, Aileen I Fernandez, Gang Han, Serena Wong, Malini Harigopal, Mirna Podoll, Kamaljeet Singh, Amy Ly, M Gabriela Kuba, Hannah Wen, Mary Ann Sanders, Jane Brock, Shi Wei, Oluwole Fadare, Krisztina Hanley, Julie Jorns, Olivia L Snir, Esther Yoon, Kim Rabe, T Rinda Soong, Emily S Reisenbichler, and David L Rimm

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The NCI Imaging Data Commons as a platform for reproducible research in computational pathology., Daniela P Schacherer, Markus D Herrmann, David A Clunie, Henning Höfener, William Clifford, William J R Longabaugh, Steve Pieper, Ron Kikinis, Andrey Fedorov, and André Homeyer

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Role of Senataxin in Amyotrophic Lateral Sclerosis., Andrew Tsui, Valentina L Kouznetsova, Santosh Kesari, Milan Fiala, and Igor F Tsigelny

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Author Correction: Lifespan-extending interventions induce consistent patterns of fatty acid oxidation in mouse livers., Kengo Watanabe, Tomasz Wilmanski, Priyanka Baloni, Max Robinson, Gonzalo G Garcia, Michael R Hoopmann, Mukul K Midha, David H Baxter, Michal Maes, Seamus R Morrone, Kelly M Crebs, Charu Kapil, Ulrike Kusebauch, Jack Wiedrick, Jodi Lapidus, Lance Pflieger, Christopher Lausted, Jared C Roach, Gwênlyn Glusman, Steven R Cummings, Nicholas J Schork, Nathan D Price, Leroy Hood, Richard A Miller, Robert L Moritz, and Noa Rappaport

Submissions from 2022

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Co-existence of chronic lymphocytic leukemia and chronic myeloid leukemia and underlying pathogenetic mechanisms., Sujan Badal, Prakash Thapaliya, and Kirstine Oh

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A biomedical open knowledge network harnesses the power of AI to understand deep human biology., Sergio E Baranzini, Katy Börner, John Morris, Charlotte A Nelson, Karthik Soman, Erica Schleimer, Michael Keiser, Mark Musen, Roger Pearce, Tahsin Reza, Brett Smith, Bruce W Herr, Boris Oskotsky, Angela Rizk-Jackson, Katherine P Rankin, Stephan J Sanders, Riley Bove, Peter W Rose, Sharat Israni, and Sui Huang

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Autoimmune Hemolytic Anemia in Children: Laboratory Investigation, Disease Associations, and Treatment Strategies., Douglas Blackall and Lily Dolatshahi

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Letter: non-invasive prediction models to exclude cirrhosis in NAFLD-not everyone fits the mould. Authors' reply., Danielle Brandman, Marie Boyle, Stuart McPherson, Mark L Van Natta, Arun J Sanyal, Kris V Kowdley, Brent Neuschwander-Tetri, Naga Chalasani, Manal F Abdelmalek, Norah A Terrault, Art McCullough, Ricki Bettencourt, Cyrielle Caussy, David E Kleiner, Cynthia Behling, James Tonascia, Quentin M Anstee, and Rohit Loomba

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Carfilzomib-Induced Thrombotic Microangiopathy: Focus on Pathogenesis., Odianosen Eigbire-Molen, Daniela Hermelin, and Douglas Blackall

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Tyrosine kinase-altered spindle cell neoplasms with EGFR internal tandem duplications., Erica Kao, Navin Pinto, Angela Trobaugh-Lotrario, Gail H Deutsch, Yu Wu, Wenjing Wang, Erin R Rudzinski, and Yajuan J Liu

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Patterns of Practice and Improvements in Survival Among Patients With Stage 2/3 Rectal Cancer Treated With Trimodality Therapy., Hagen F Kennecke, Henry T Bahnson, Bruce Lin, Colin O'Rourke, Jennifer Kaplan, Huong Pham, Andrew Suen, and Vlad V Simianu

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More autopsy studies are needed to understand the pathogenesis of severe COVID-19., Scott P Layne, Kathie-Anne Walters, John C Kash, and Jeffery K Taubenberger

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Reconsidering the in vivo functions of Clostridial Stickland amino acid fermentations., Aidan Pavao, Madeline Graham, Mario L Arrieta-Ortiz, Selva Rupa Christinal Immanuel, Nitin S Baliga, and Lynn Bry

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December 2022: Region 10 Emerging Special Pathogen Treatment Center (RESPTC) at Providence Sacred Heart Medical Center & Children’s Hospital, Providence - Special Pathogens Program

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September 2022: Region 10 Emerging Special Pathogen Treatment Center (RESPTC) at Providence Sacred Heart Medical Center & Children’s Hospital, Providence - Special Pathogens Program

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Mutations of FH and IDH may induce gliomagenesis by similar mechanisms., Aditya Raghunathan, Cristiane M Ida, Erick M Westbroek, Sounak Gupta, Robert B Jenkins, Caterina Giannini, and Kenneth D Aldape

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Malignant Pilomatricoma of the Lower Extremity: A Difficult and Rare Diagnosis., Chaitra Subramanyam, Paige Dyrek, Xu Yao, and Martin H Kay

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Multiple early factors anticipate post-acute COVID-19 sequelae., Yapeng Su, Dan Yuan, Daniel G Chen, Rachel H Ng, Kai Wang, Jongchan Choi, Sarah Li, Sunga Hong, Rongyu Zhang, Jingyi Xie, Sergey A Kornilov, Kelsey Scherler, Ana Jimena Pavlovitch-Bedzyk, Shen Dong, Christopher Lausted, Inyoul Lee, Shannon Fallen, Chengzhen L Dai, Priyanka Baloni, Brett Smith, Venkata R Duvvuri, Kristin G Anderson, Jing Li, Fan Yang, Caroline J Duncombe, Denise J McCulloch, Clifford Rostomily, Pamela Troisch, Jing Zhou, Sean Mackay, Quinn DeGottardi, Damon H May, Ruth Taniguchi, Rachel M Gittelman, Mark Klinger, Thomas M Snyder, Ryan Roper, Gladys Wojciechowska, Kim Murray, Rick Edmark, Simon Evans, Lesley Jones, Yong Zhou, Lee Rowen, Rachel Liu, William Chour, Heather A Algren, William R Berrington, Julie A Wallick, Rebecca A. Cochran, Mary Micikas, ISB-Swedish COVID-19 Biobanking Unit, Terri Wrin, Christos J Petropoulos, Hunter R Cole, Trevan Fischer, Wei Wei, Dave Hoon, Nathan D Price, Naeha Subramanian, Joshua A Hill, Jennifer J Hadlock, Andrew T Magis, Antoni Ribas, Lewis L Lanier, Scott D Boyd, Jeffrey A Bluestone, Helen Chu, Leroy Hood, Raphael Gottardo, Philip D Greenberg, Mark M Davis, Jason D Goldman, and James R Heath

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Mathematical models to study the biology of pathogens and the infectious diseases they cause., Joao B Xavier, Jonathan M Monk, Saugat Poudel, Charles J Norsigian, Anand V Sastry, Chen Liao, Jose Bento, Marc A Suchard, Mario L Arrieta-Ortiz, Eliza Jr Peterson, Nitin Baliga, Thomas Stoeger, Felicia Ruffin, Reese A K Richardson, Catherine A Gao, Thomas D Horvath, Anthony M Haag, Qinglong Wu, Tor Savidge, and Michael R Yeaman

Submissions from 2021

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Minimal Residual Disease in Myeloma: Application for Clinical Care and New Drug Registration., Kenneth C Anderson, Daniel Auclair, Stacey J Adam, Amit Agarwal, Melissa Anderson, Herve Avet-Loiseau, Mark Bustoros, Jessica Chapman, Dana E Connors, Ajeeta Dash, Alessandra Di Bacco, Ling Du, Thierry Facon, Juan Flores-Montero, Francesca Gay, Irene M Ghobrial, Nicole J Gormley, Ira Gupta, Howard Higley, Jens Hillengass, Bindu Kanapuru, Dickran Kazandjian, Gary J Kelloff, Ilan R Kirsch, Brandon E Kremer, Ola Landgren, Elizabeth D Lightbody, Oliver C Lomas, Sagar Lonial, Maria Victoria Mateos, Rocio Montes de Oca, Lata Mukundan, Nikhil C Munshi, Elizabeth K O'Donnell, Alberto Orfao, Bruno Paiva, Reshma Patel, Trevor J Pugh, Karthik Ramasamy, Jill Ray, Mikhail Roshal, Jeremy A Ross, Caroline C Sigman, Katie L Thoren, Suzanne Trudel, Gary A Ulaner, Nancy Valente, Brendan M Weiss, Elena Zamagni, and Shaji K Kumar

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Performance characteristics of the Roche Diagnostics cobas® Liat® PCR System as a COVID-19 screening tool for hospital admissions in a regional healthcare delivery system., Douglas Blackall, Raymond Moreno, Justin Jin, Rachel Plotinsky, Ronald Dworkin, and Margret Oethinger

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Recent Progress in Lyme Disease and Remaining Challenges., Jason R Bobe, Brandon L Jutras, Elizabeth J Horn, Monica E Embers, Allison Bailey, Robert L Moritz, Ying Zhang, Mark J Soloski, Richard S Ostfeld, Richard T Marconi, John Aucott, Avi Ma'ayan, Felicia Keesing, Kim Lewis, Choukri Ben Mamoun, Alison W Rebman, Mecaila E McClune, Edward B Breitschwerdt, Panga Jaipal Reddy, Ricardo Maggi, Frank Yang, Bennett Nemser, Aydogan Ozcan, Omai Garner, Dino Di Carlo, Zachary Ballard, Hyou-Arm Joung, Albert Garcia-Romeu, Roland R Griffiths, Nicole Baumgarth, and Brian A Fallon

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A redox-active crosslinker reveals an essential and inhibitable oxidative folding network in the endoplasmic reticulum of malaria parasites., David W Cobb, Heather M Kudyba, Alejandra Villegas, Michael R Hoopmann, Rodrigo P Baptista, Baylee Bruton, Michelle Krakowiak, Robert L Moritz, and Vasant Muralidharan

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Laboratory and Clinical Implications of Incidental and Secondary Germline Findings During Tumor Testing., Allison Cushman-Vokoun, Josh Lauring, John Pfeifer, Damon R Olson, Anna Berry, John Thorson, Karl Voelkerding, Jonathan Myles, James Barbeau, Pranil Chandra, Marilyn Li, Gail H Vance, Brad W Jensen, Molly Y Hansen, and Sophia Yohe

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Lower blood malondialdehyde is associated with past pesticide exposure: findings in Gulf War illness and healthy controls., Beatrice Alexandra Golomb, Sridevi Devaraj, Alexis K Messner, Hayley Jean Koslik, Jun Hee Han, and Barnabas Yik

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Measuring the Efficacy of Pathology Career Recruitment Strategies in US Medical Students., Patricia V Hernandez, Dana Razzano, Nicole D Riddle, John T Fallon, Humayun K Islam, Kamran M Mirza, Rugved Pattarkine, Tania Platero, Daniela Hermelin, Patricia V Adem, Adam L Booth, Eunice Mbela Nachinga, Kalpana S Reddy, Angelica Mares, and Patrick A Lento

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Reducing Specimen Labeling Errors to Promote Patient Safety: A Quality Improvement Project at an Inpatient Department in a Regional Acute Care Hospital, Jihye Johnson

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Congenital Myenteric Hypoganglionosis., Raj P Kapur, Andrew M Bellizzi, Steffan Bond, Haiying Chen, Jeong S Han, Robin D LeGallo, Craig Midgen, Alysa A Poulin, Naseem Uddin, Mikako Warren, José E Velázquez Vega, and Craig W Zuppan

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Diagnostic Concordance of Cytology and Histology in Samples Obtained via Endoscopic Ultrasound-Guided Fine-Needle Biopsy (EUS-FNB)., Tara Keihanian, Liege Diaz, Liza Plafsky, Uday Shergill, Jinendra Satiya, Rtika Abraham, Monica Garcia-Buitrago, James H Tabibian, and Mohit Girotra

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Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamous cell carcinoma., Rom Leidner, Marka Crittenden, Kristina Young, Hong Xiao, Yaping Wu, Marcus A Couey, Ashish A Patel, Allen C Cheng, Amber L Watters, Carlo Bifulco, George Morris, Lessli Rushforth, Shorin Nemeth, Walter J Urba, Michael Gough, and R Bryan Bell

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Phosphorylation of SMAD3 in immune cells predicts survival of patients with early stage non-small cell lung cancer., Sebastian Marwitz, Carmen Ballesteros-Merino, Shawn M. Jensen, Martin Reck, Christian Kugler, Sven Perner, Daniel Drömann, Torsten Goldmann, and Bernard A Fox

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Induction of ADAM10 by RT drives fibrosis, resistance, and EMT in pancreatic cancer., Adam C Mueller, Miles Piper, Andrew Goodspeed, Shiv Bhuvane, Jason S Williams, Shilpa Bhatia, Andy V Phan, Benjamin Van Court, Kathryn L Zolman, Brisa Peña, Ayman J Oweida, Sara Zakem, Cheryl Meguid, Michael W Knitz, Laurel Darragh, Thomas E Bickett, Jacob Gadwa, Luisa Mestroni, Matthew R G Taylor, Kimberly R Jordan, Peter Dempsey, M Scott Lucia, Martin D McCarter, Marco Del Chiaro, Wells A Messersmith, Richard D Schulick, Karyn A Goodman, Michael J. Gough, Casey S Greene, James C Costello, Antonio Galvao Neto, David Lagares, Kirk C Hansen, Adrie Van Bokhoven, and Sana D Karam

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A Randomized Phase II Study of Androgen Deprivation Therapy with or without Palbociclib in RB-positive Metastatic Hormone Sensitive Prostate Cancer (mHSPC)., Phillip L Palmbos, Stephanie Daignault-Newton, Scott A Tomlins, Neeraj Agarwal, Przemyslaw Twardowski, Alicia K Morgans, William K Kelly, Vivek K Arora, Emmanuel S Antonarakis, Javed Siddiqui, Jon Jacobson, Mathew S Davenport, Dan R Robinson, Arul M Chinnaiyan, Karen E Knudsen, and Maha Hussain

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Anticoagulation Therapy Reduces Recurrent Stroke in Embolic Stroke of Undetermined Source Patients With Elevated Coagulation Markers or Severe Left Atrial Enlargement., Kishan Patel, Elio Mikhael, Michael Liu, Srikant Rangaraju, Deandra Ellis, Alexander Duncan, Samir Belagaje, Trina Belair, Laura Henriquez, and Fadi Nahab

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The Hidden Cost of Hemolyzed Blood Samples in the Emergency Department., Michael P Phelan, Christopher Ramos, Laura E Walker, Gerald Richland, and Edmunds Z Reineks

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Efficient antigen cross-presentation through coating conventional aluminum adjuvant particles with PEI., Hongyan Ren, Yongbin Mou, Lin Lin, Lixin Wang, and Hongming Hu

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A Curriculum for Genomic Education of Molecular Genetic Pathology Fellows:A Report of the Association for Molecular Pathology Training and Education Committee., Jason N Rosenbaum, Anna B Berry, Alanna J Church, Kristy Crooks, Jeffrey R Gagan, Dolores López-Terrada, John D Pfeifer, Hanna Rennert, Iris Schrijver, Anthony N Snow, David Wu, and Mark D Ewalt

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Anti-GBM nephritis with mesangial IgA deposits after SARS-CoV-2 mRNA vaccination., Allan Sacker, Vanderlene Kung, and Nicole Andeen

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Developing an enhanced 7-color multiplex IHC protocol to dissect immune infiltration in human cancers., Zhaoyu Sun, Richard Nyberg, Yaping Wu, Brady Bernard, and William L. Redmond

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Intratumoral Plasmid IL12 Expands CD8, Melinda L Telli, Hiroshi Nagata, Irene Wapnir, Chaitanya R Acharya, Kaitlin Zablotsky, Bernard A Fox, Carlo Bifulco, Shawn M. Jensen, Carmen Ballesteros-Merino, Mai Hope Le, Robert H Pierce, Erica Browning, Reneta Hermiz, Lauren Svenson, Donna Bannavong, Kim Jaffe, Jendy Sell, Kellie Malloy Foerter, David A Canton, Christopher G Twitty, Takuya Osada, H Kim Lyerly, and Erika J Crosby

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Genetic deletion of Polo-like kinase 2 reduces alpha-synuclein serine-129 phosphorylation in presynaptic terminals but not Lewy bodies., Leah J Weston, Teresa L Stackhouse, Kateri Spinelli, Sydney W Boutros, Elizabeth P Rose, Valerie R Osterberg, Kelvin C Luk, Jacob Raber, Tamily A Weissman, and Vivek K Unni

Submissions from 2020

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Estrogen and Progesterone Receptor Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Guideline Update., Kimberly H Allison, M Elizabeth H Hammond, Mitchell Dowsett, Shannon E McKernin, Lisa A Carey, Patrick L Fitzgibbons, Daniel F Hayes, Sunil R Lakhani, Mariana Chavez-MacGregor, Jane Perlmutter, Charles M Perou, Meredith M Regan, David L Rimm, W Fraser Symmans, Emina E Torlakovic, Leticia Varella, Giuseppe Viale, Tracey F Weisberg, Lisa M McShane, and Antonio C Wolff

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Estrogen and Progesterone Receptor Testing in Breast Cancer: ASCO/CAP Guideline Update., Kimberly H Allison, M Elizabeth H Hammond, Mitchell Dowsett, Shannon E McKernin, Lisa A Carey, Patrick L Fitzgibbons, Daniel F Hayes, Sunil R Lakhani, Mariana Chavez-MacGregor, Jane Perlmutter, Charles M Perou, Meredith M Regan, David L Rimm, W Fraser Symmans, Emina E Torlakovic, Leticia Varella, Giuseppe Viale, Tracey F Weisberg, Lisa M McShane, and Antonio C Wolff

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Intravascular Lymphoma with Progressive CNS Hemorrhage and Multiple Dissections., Ricky Chen, Gurjeet Singh, J Scott McNally, Cheryl A Palmer, and Adam de Havenon

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Not in the Same Vein: Inflammatory Bowel Disease, Malignancy, and Enterocolic Lymphocytic Phlebitis., Orly N Farber, Alexa Weingarden, Christopher Lee, David R Braxton, David Bingham, Gregory Scott, Nielsen Fernandez-Becker, Daniel Goff, Andrew Shelton, and Cindy Kin

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Refractory scleroderma renal crisis precipitated after high-dose oral corticosteroids and concurrent intravitreal injection of bevacizumab., Ramy M Hanna, Lama Abdelnour, Jonathan E Zuckerman, Antoney J Ferrey, Alex Pai, Kambiz Vahabzadeh, James Wilson, Everado A Torres, Kamyar Kalantar-Zadeh, and Ira B Kurtz

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Vanishing Twins Conceived Through Fresh In Vitro Fertilization: Obstetric Outcomes and Placental Pathology., Amy L Harris, Caitlin R Sacha, Kristen M Basnet, Kaitlyn E James, Taylor S Freret, Anjali J Kaimal, John Yeh, Irene Souter, Drucilla J Roberts, and Thomas L Toth

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Association of Event-Free and Distant Recurrence-Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer: Three-Year Follow-up Analysis for the I-SPY2 Adaptively Randomized Clinical Trial., I-SPY2 Trial Consortium, Douglas Yee, Angela M DeMichele, Christina Yau, Claudine Isaacs, W Fraser Symmans, Kathy S Albain, Yunn-Yi Chen, Gregor Krings, Shi Wei, Shuko Harada, Brian Datnow, Oluwole Fadare, Molly Klein, Stefan Pambuccian, Beiyun Chen, Kathi Adamson, Sharon Sams, Paulette Mhawech-Fauceglia, Anthony Magliocco, Mike Feldman, Mara Rendi, Husain Sattar, Jay Zeck, Idris T Ocal, Ossama Tawfik, Lauren Grasso LeBeau, Sunati Sahoo, Tuyethoa Vinh, A Jo Chien, Andres Forero-Torres, Erica Stringer-Reasor, Anne M Wallace, Lajos Pusztai, Judy C Boughey, Erin D Ellis, Anthony D Elias, Janice Lu, Julie E Lang, Hyo S Han, Amy S Clark, Rita Nanda, Donald W Northfelt, Qamar J Khan, Rebecca K Viscusi, David M Euhus, Kirsten K Edmiston, Stephen Y Chui, Kathleen Kemmer, John W Park, Minetta C Liu, Olufunmilayo Olopade, Brian Leyland-Jones, Debasish Tripathy, Stacy L Moulder, Hope S Rugo, Richard Schwab, Shelly Lo, Teresa Helsten, Heather Beckwith, Patricia Haugen, Nola M Hylton, Laura J Van't Veer, Jane Perlmutter, Michelle E Melisko, Amy Wilson, Garry Peterson, Adam L Asare, Meredith B Buxton, Melissa Paoloni, Julia L Clennell, Gillian L Hirst, Ruby Singhrao, Katherine Steeg, Jeffrey B Matthews, Smita M Asare, Ashish Sanil, Scott M Berry, Laura J Esserman, and Donald A Berry

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Pathologic assessment of endoscopic resection specimens with superficial carcinoma of the esophagus: current practice and practical issues., Esmeralda Celia Marginean and Jain Dhanpat

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Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer., Bernhard Mlecnik, Carlo Bifulco, Gabriela Bindea, Florence Marliot, Alessandro Lugli, J Jack Lee, Inti Zlobec, Tilman T Rau, Martin D Berger, Iris D Nagtegaal, Elisa Vink-Börger, Arndt Hartmann, Carol Geppert, Julie Kolwelter, Susanne Merkel, Robert Grützmann, Marc Van den Eynde, Anne Jouret-Mourin, Alex Kartheuser, Daniel Léonard, Christophe Remue, Julia Y Wang, Prashant Bavi, Michael H A Roehrl, Pamela S Ohashi, Linh T Nguyen, SeongJun Han, Heather L MacGregor, Sara Hafezi-Bakhtiari, Bradly G Wouters, Giuseppe V Masucci, Emilia K Andersson, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Kristyna Nemejcova, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Ciliberto, Michele Maio, Luigi Laghi, Fabio Grizzi, Tessa Fredriksen, Bénédicte Buttard, Lucie Lafontaine, Daniela Bruni, Anastasia Lanzi, Carine El Sissy, Nacilla Haicheur, Amos Kirilovsky, Anne Berger, Christine Lagorce, Christopher Paustian, Carmen Ballesteros-Merino, Jeroen Dijkstra, Carlijn van de Water, Shannon van Lent-van Vliet, Nikki Knijn, Ana-Maria Muşină, Dragos-Viorel Scripcariu, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Toshihiko Torigoe, Noriyuki Sato, Tomohisa Furuhata, Ichiro Takemasa, Kyogo Itoh, Prabhu S Patel, Hemangini H Vora, Birva Shah, Jayendrakumar B Patel, Kruti N Rajvik, Shashank J Pandya, Shilin N Shukla, Yili Wang, Guanjun Zhang, Yutaka Kawakami, Francesco M Marincola, Paolo A Ascierto, Bernard A Fox, Franck Pagès, and Jérôme Galon

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Effects of Radiation on the Tumor Microenvironment., Arta M Monjazeb, Kurt A Schalper, Franz Villarroel-Espindola, Anthony Nguyen, Stephen L Shiao, and Kristina H Young

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Schwannoma of the Nasal Ala in a 13 Year-Old Boy., Christopher Nyte and William D Ryan

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Investigating the Effects of Brainstem Neuronal Adaptation on Cardiovascular Homeostasis., James H Park, Jonathan Gorky, Babatunde Ogunnaike, Rajanikanth Vadigepalli, and James S Schwaber

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IRE1α and IGF signaling predict resistance to an endoplasmic reticulum stress-inducing drug in glioblastoma cells., Jeffrey J Rodvold, Su Xian, Julia Nussbacher, Brian Tsui, T Cameron Waller, Stephen C Searles, Alyssa Lew, Pengfei Jiang, Ivan Babic, Natsuko Nomura, Jonathan H Lin, Santosh Kesari, Hannah Carter, and Maurizio Zanetti

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Composition of Caenorhabditis elegans extracellular vesicles suggests roles in metabolism, immunity, and aging., Joshua C Russell, Taek-Kyun Kim, Ayush Noori, Gennifer E Merrihew, Julia E Robbins, Alexandra Golubeva, Kai Wang, Michael J MacCoss, and Matt Kaeberlein

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Abstract 14090: Multiparity is Associated With Aortic Pathology in Women From the Dallas Heart Study, Kavisha Singh, Rina Mauricio, Wanpen Vongpatanasin, Katy Lonergan, Monika Sanghavi, Amit Khera, James A De Lemos, Colby Ayers, and Parag H. Joshi

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Effect of various decontamination procedures on disposable N95 mask integrity and SARS-CoV-2 infectivity., Jeffrey S Smith, Haley Hanseler, John Welle, Rogan Rattray, Mary Campbell, Tacy Brotherton, Tarsem Moudgil, Thomas F Pack, Keith Wegmann, Shawn Jensen, Justin Jin, Carlo B Bifulco, Scott A Prahl, Bernard A Fox, and Nicholas L Stucky

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Submucosal Supernumerary Smooth Muscle Coat: A Common Histologic Finding in Mowat-Wilson Syndrome With or Without Hirschsprung Disease., Mariko Suchi, Casey M Calkins, Ashish Chogle, Jesse Steffan Bond, and Raj P Kapur

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Demonstration of reciprocal diurnal variation in human serum T3 and rT3 concentration demonstrated by mass spectrometric analysis and establishment of thyroid hormone reference intervals., Qian Sun, Lívia Avallone, Brian Stolze, Katherine A Araque, Yesim Özarda, Jacqueline Jonklaas, Toral Parikh, Kerry Welsh, Likhona Masika, and Steven J Soldin

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Sequential Complications of Hypercalcemia, Necrotizing Granulomatous Vasculitis, and Aplastic Anemia Occurring in One Patient with Angioimmunoblastic T-cell Lymphoma., Sriman Swarup, Jonathan Kopel, Kyaw Zin Thein, Kaiser Tarafdar, Khatrina Swarup, Seshadri Thirumala, and Donald P Quick

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Loss of switch/sucrose non-fermenting complex protein expression in undifferentiated gastrointestinal and pancreatic carcinomas., Basile Tessier-Cloutier, David F Schaeffer, Julinor Bacani, Celia E Marginean, Steve Kalloger, Martin Köbel, and Cheng-Han Lee

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Fractal Deposits of a Hemostatic Hydrophilic Polymer in Mohs Micrographic Surgery Frozen Sections: A Histologic Analysis and Comparison With Sodium Polystyrene Sulfonate (Kayexalate)., Danielle Urman, Jennifer Ledon, Steven E Kolker, and Richard G Bennett