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Publication Date



2021 prov rn wa; 2021 prov rn poster; washington; spokane; pshmc


Cardiology | Nursing


Background: Familial Hypercholesterolemia (FH) is the most common genetic condition resulting in cardiovascular disease, a leading cause of death in the United States. FH is estimated to affect 1 in 250 individuals with elevated lipid levels present from birth. An estimated 90% of individuals with FH remain undiagnosed. '

Purpose: The purpose of this quality improvement project was to increase provider awareness and promote screening for FH among adults ages 20 years and older. '

Methods: This quality improvement project consisted of an online educational intervention for providers working at an outpatient clinic regarding FH. Outcomes included: 1) pre-intervention lipid screening practices at the point of admission and every five years; 2) pre-intervention treatment status for clients exceeding the LDL-C 190 mg/dl cut-point; and 3) post-intervention lipid screening practice changes. Assessment of providers' FH knowledge occurred with author created surveys, and a retrospective chart review provided information on documentation of lipid screening practices as well as the proportion of patients screened for FH before and after the educational intervention.

Results: Outcome measures of FH knowledge were reported using descriptive statistics. An independent samples t-test showed no statistically significant change in screening practices pre/post-intervention (p = 0.976), with a mean interval of 2.09 years between initial and subsequent testing. Regression analysis yielded a medium correlation effect between age and lipid testing intervals, decreasing by .028 years for every one-year increase in age. The proportion of clinic patients exceeding the expected population estimate for FH was significant (p<.001). Return of clinical impact survey data did not occur.

Conclusions: Electronic Medical Record data identified undiagnosed patients in the clinic population at risk for FH. Knowledge surveys identified themes for further provider FH education.

Clinical Institute

Cardiovascular (Heart)





Conference / Event Name

2021 Providence RN Conference


Virtual Conference

Improving Primary Care Screening for Familial Hypercholesterolemia