Abnormal Fetal Findings Associated With a Global Sphericity Index of the 4-Chamber View Below the 5th Centile.
Publication Title
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
Document Type
Article
Publication Date
11-1-2017
Keywords
california
Abstract
OBJECTIVES: The purpose of this study was to evaluate the global sphericity index (GSI) of the 4-chamber view and correlate the results with abnormal ultrasound findings.
METHODS: The epicardial end-diastolic basal-apical length (BAL) and transverse length (TL) of the 4-chamber view were measured to compute the GSI (BAL/TL) in 200 control fetuses between 20 and 40 weeks' gestation. Three hundred study fetuses were prospectively examined between 17 and 39 weeks' gestation. The GSI, Z score, and centile were computed for each of the fetuses.
RESULTS: The GSI (1.233; SD, 0.0953) in the control fetuses was independent of gestational age. Eighteen percent of the study fetuses (55 of 300) had a GSI below the 5th centile (< 1.08), of whom 96% (53 of 55) had additional abnormal ultrasound findings. Fetuses with an estimated fetal weight below the 10th centile had a significantly (P < .05) higher rate of an umbilical artery Doppler pulsatility index above the 95th centile (27% versus 17.7%), a middle cerebral artery Doppler pulsatility index below the 5th centile (27% versus 0%), an abnormal cerebroplacental ratio (27% versus 4.5%), and an amniotic fluid index of less than 5 cm (36% versus 9%). The TL was significantly increased compared with the BAL in fetuses with cardiac dysfunction, irrespective of the estimated fetal weight.
CONCLUSIONS: An abnormal GSI below the 5th centile is associated with abnormal fetal ultrasound findings.
Area of Special Interest
Women & Children
Area of Special Interest
Cardiovascular (Heart)
Specialty/Research Institute
Perinatology/Neonatology
Specialty/Research Institute
Obstetrics & Gynecology
Specialty/Research Institute
Pediatrics
DOI
10.1002/jum.14261
