Bioprosthetic Aortic Valve Durability: A Meta-Regression of Published Studies.
Publication Title
The Annals of thoracic surgery
Document Type
Article
Publication Date
9-1-2017
Keywords
Animals; Aortic Valve; Bioprosthesis; Heart Valve Diseases; Heart Valve Prosthesis; Humans; Prosthesis Design; cards
Abstract
To compare structural valve deterioration (SVD) among bioprosthetic aortic valve types, a PubMed search found 54 papers containing SVD-free curves extending to at least 10 years. The curves were digitized and fit to Weibull distributions, and the mean times to valve failure (MTTF) were calculated. Twelve valve models were collapsed into four valve types: Medtronic (Medtronic, Minneapolis, MN) and Edwards (Edwards Lifesciences, Irvine, CA) porcine; and Sorin (Sorin Group [now LivaNova], London, United Kingdom) and Edwards pericardial. Meta-regression found MTTF was associated with the patient's age, publication year, SVD definition, and valve type. Sorin pericardial valves had significantly lower risk-adjusted MTTF (higher SVD risk), and there were no significant differences in MTTF among the other three valve types.
Area of Special Interest
Cardiovascular (Heart)
Specialty/Research Institute
Cardiology
Specialty/Research Institute
Center for Cardiovascular Analytics, Research + Data Science (CARDS)
