Biological BMI uncovers hidden health risks and is more responsive to lifestyle shifts
Publication Title
Nature Medicine
Document Type
Article
Publication Date
4-11-2023
Keywords
washington; isb
Abstract
Body mass index (BMI) is a clinically useful obesity measure that shows an association with healthspan and lifespan. We developed ‘biological BMI’ scores, calculated from multi-omics data (proteins and metabolites) and clinical laboratory tests from blood. We show that a biological BMI more accurately reflects metabolic health and is more responsive to lifestyle changes than a classically measured BMI.
Area of Special Interest
Digestive Health
Specialty/Research Institute
Institute for Systems Biology
DOI
10.1038/s41591-023-02283-x
