Biological BMI uncovers hidden health risks and is more responsive to lifestyle shifts

Authors

Noa Rappaport, Institute for Systems Biology, Seattle, WA, USA.Follow
Kengo Watanabe, Institute for Systems Biology, Seattle, WA, USA

Document Type

Article

Publication Date

4-11-2023

Publication Title

Nature Medicine

Keywords

washington; isb

Abstract

Body mass index (BMI) is a clinically useful obesity measure that shows an association with healthspan and lifespan. We developed ‘biological BMI’ scores, calculated from multi-omics data (proteins and metabolites) and clinical laboratory tests from blood. We show that a biological BMI more accurately reflects metabolic health and is more responsive to lifestyle changes than a classically measured BMI.

Clinical Institute

Digestive Health

Department

Institute for Systems Biology

Recommended Citation

Rappaport, Noa and Watanabe, Kengo, "Biological BMI uncovers hidden health risks and is more responsive to lifestyle shifts" (2023). Articles, Abstracts, and Reports. 7244.
https://digitalcommons.providence.org/publications/7244