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Submissions from 2022

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Lenvatinib dose, efficacy, and safety in the treatment of multiple malignancies., Robert J Motzer, Matthew H Taylor, Thomas R Jeffry Evans, Takuji Okusaka, Hilary Glen, Gregory M Lubiniecki, Corina Dutcus, Alan D Smith, Chinyere E Okpara, Ziad Hussein, Seiichi Hayato, Toshiyuki Tamai, and Vicky Makker

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Cost-effectiveness of prophylactic retropubic sling at the time of vaginal prolapse surgery., Tsung Mou, Lauren A Cadish, Elizabeth L Gray, and C Emi Bretschneider

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Workforce Characteristics of Med-Peds Hospitalists., Roma Moza, David Fish, and Rachel J Peterson

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Radiotherapy for Plantar Fibromas (Ledderhose Disease)., John D Mozena, Eric K Hansen, and Paul Clint Jones

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Standardized annotation of translated open reading frames., Jonathan M Mudge, Jorge Ruiz-Orera, John R Prensner, Marie A Brunet, Ferriol Calvet, Irwin Jungreis, Jose Manuel Gonzalez, Michele Magrane, Thomas F Martinez, Jana Felicitas Schulz, Yucheng T Yang, M Mar Albà, Julie L Aspden, Pavel V Baranov, Ariel A Bazzini, Elspeth Bruford, Maria Jesus Martin, Lorenzo Calviello, Anne-Ruxandra Carvunis, Jin Chen, Juan Pablo Couso, Eric W Deutsch, Paul Flicek, Adam Frankish, Mark Gerstein, Norbert Hubner, Nicholas T Ingolia, Manolis Kellis, Gerben Menschaert, Robert L Moritz, Uwe Ohler, Xavier Roucou, Alan Saghatelian, Jonathan S Weissman, and Sebastiaan van Heesch

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Therapeutic Value of Sentinel Lymph Node Biopsy in Patients With Melanoma: A Randomized Clinical Trial., Multicenter Selective Lymphadenectomy Trials Study Group, Jessica S Crystal, John F Thompson, John Hyngstrom, Corrado Caracò, Jonathan S Zager, Tiina Jahkola, Tawnya L Bowles, Elisabetta Pennacchioli, Peter D Beitsch, Harald J Hoekstra, Marc Moncrieff, Christian Ingvar, Alexander van Akkooi, Michael S Sabel, Edward A Levine, Doreen Agnese, Michael Henderson, Reinhard Dummer, Rogerio I Neves, Carlo Riccardo Rossi, John M Kane, Steven Trocha, Frances Wright, David R Byrd, Maurice Matter, Eddy C Hsueh, Alastair MacKenzie-Ross, Mark Kelley, Patrick Terheyden, Tara L Huston, Jeffrey D Wayne, Heather Neuman, B Mark Smithers, Charlotte E Ariyan, Darius Desai, Jeffrey E Gershenwald, Shlomo Schneebaum, Anja Gesierich, Lisa K Jacobs, James M Lewis, Kelly M McMasters, Cristina O'Donoghue, Andre van der Westhuizen, Armando Sardi, Richard Barth, Robert Barone, J Greg McKinnon, Craig L Slingluff, Jeffrey M Farma, Erwin Schultz, Randall P Scheri, Sergi Vidal-Sicart, Manuel Molina, Alessandro A E Testori, Lee Foshag, Lisa Van Kreuningen, He-Jing Wang, Myung-Shin Sim, Richard A Scolyer, David E Elashoff, Alistair J Cochran, and Mark B Faries

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Trends in treatment patterns and costs of care among patients with advanced stage cervical cancer., Fernanda Musa, Elizabeth Brouwer, Jie Ting, Naomi R M Schwartz, Andy Surinach, Lisa Bloudek, and Scott D Ramsey

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Management of Post-Infectious Anosmia and Hyposmia: A Systematic Review., Amit K Nag, Abdul K Saltagi, Mohamad Z Saltagi, Arthur W Wu, Thomas S Higgins, Anna Knisely, Jonathan Y Ting, and Elisa A Illing

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CT250 / 11 - A first-in-human phase 1 study of NL-201 in patients with relapsed or refractory cancer, Aung Naing, Brendan Curti, and See full list of authors in comments

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Comparison of push-dose phenylephrine and epinephrine in the emergency department., Elizabeth Nam, Scott Fitter, and Kayvan Moussavi

Treatment Utilization/Outcomes for Locally Advanced Rectal Cancer in Elderly Patients: Analysis of the NCDB, S Nassoiy, SC Chang, and See all authors in comments

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Treatment Utilization and Outcomes for Locally Advanced Rectal Cancer in Older Patients., Sean Nassoiy, Wade Christopher, Rebecca Marcus, Jennifer Keller, Jessica Weiss, Shu-Ching Chang, Leland Foshag, Richard Essner, Trevan Fischer, and Melanie Goldfarb

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Evolving management of early stage pancreatic adenocarcinoma in older patients., Sean Nassoiy, Wade O Christopher, Rebecca Marcus, Jennifer Keller, Jessica Weiss, Shu-Ching Chang, Richard Essner, Lee Foshag, Trevan Fischer, and Melanie Goldfarb

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Instrument selection for the ASAS core outcome set for axial spondyloarthritis., Victoria Navarro-Compán, Anne Boel, Annelies Boonen, Philip Mease, Maxime Dougados, Uta Kiltz, Robert B M Landewé, Xenofon Baraliakos, Wilson Bautista-Molano, Praveena Chiowchanwisawakit, Hanne Dagfinrud, Lara Fallon, Marco Garrido-Cumbrera, Lianne Gensler, Bassel Kamal ElZorkany, Nigil Haroon, Yu Heng Kwan, Pedro M Machado, Walter Maksymowych, Anna Molto, Natasha de Peyrecave, Denis Poddubnyy, Mikhail Protopopov, Sofia Ramiro, In-Ho Song, Salima van Weely, and Désirée van der Heijde

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GLP-1 Receptor Agonists in the Treatment of Patients with Type 2 Diabetes and Chronic Kidney Disease, Joshua J. Neumiller, Radica Alicic, and Katherine R. Tuttle

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Clinical Evidence and Proposed Mechanisms for Cardiovascular and Kidney Benefits from Sodium-Glucose Co-transporter-2 Inhibitors., Joshua J Neumiller, Fredrick J Lienhard, Radica Alicic, and Katherine Tuttle

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Clinical Evidence and Proposed Mechanisms for Cardiovascular and Kidney Benefits from Sodium-Glucose Co-transporter-2 Inhibitors., Joshua J Neumiller, Fredrick J Lienhard, Radica Z Alicic, and Katherine R Tuttle

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Optimizing use of SGLT2 inhibitors and other evidence-based therapies to improve outcomes in patients with type 2 diabetes and chronic kidney disease: An opportunity for pharmacists., Joshua J Neumiller, Jay H Shubrook, Tom Manley, Radica Alicic, and Katherine Tuttle

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Cesarean delivery on maternal request in the United States from 1999 to 2015: a comment., David L Newfield

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Constraint-Based Reconstruction and Analyses of Metabolic Models: Open-Source Python Tools and Applications to Cancer., Rachel H Ng, Jihoon W Lee, Priyanka Baloni, Christian Diener, James R Heath, and Yapeng Su

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Surgical Site Infection in Thoracic Surgery Is Not Associated With Perioperative Hypothermia., Albert P Nguyen, Minh Tran, Swapnil Khoche, Rodney A Gabriel, and Ulrich Schmidt

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Black Lives Matter: Moving from passion to action in academic medical institutions., Bich-May Nguyen, Jessica Guh, and Brandi Freeman

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GPR17 Signaling Activation by CHBC Agonist Induced Cell Death via Modulation of MAPK Pathway in Glioblastoma., Phung Nguyen, Phuong Doan, Akshaya Murugesan, Thiyagarajan Ramesh, Tatu Rimpilainen, Nuno R Candeias, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

The Effect of Center Transplant Rate and the Use of Temporary Mechanical Circulatory Support on Heart Transplant Outcomes, V Nguyen, Jacob Abraham, Sophia Airhart, J Kay, and K Koomalsingh

Increased Drug Intoxications Seen in Heart Transplant Donors During COVID-19 Pandemic, V Nguyen, Jacob Abraham, J Gelow, K Koomalsingh, and D Oseran

Cardiogenic Shock by SCAI Classification in Patients Awaiting Heart Transplantation, V Nguyen, J Gelow, and Jacob Abraham

The Effect of Center Transplant Rate and the Use of Temporary Mechanical Circulatory Support on Heart Transplant Outcomes, Vidang P. Nguyen, Jacob Abraham, Sophia Airhart, Jill M Gelow, J Kay, and Kevin Koomalsingh

Increased Drug Intoxications Seen in Heart Transplant Donors During COVID-19 Pandemic, Vidang P. Nguyen, Jacob Abraham, Jill M Gelow, Kevin Koomalsingh, and Daniel S. Oseran

ASN In The Loop: “Disparities in the Use of Sodium Glucose Co-transporter 2 Inhibitors and Glucagon-like Peptie-1 Receptor Agonist in Adults with Chronic Kidney Disease”, Susanne B. Nicholas, Radica Alicic, and Jenny Shen

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Organ-Based Proteome and Post-Translational Modification Profiling of a Widely Cultivated Tropical Water Fish, Labeo rohita, Mehar Un Nissa, Nevil Pinto, Arijit Mukherjee, Panga Jaipal Reddy, Biplab Ghosh, Zhi Sun, Saicharan Ghantasala, Chetanya Chetanya, Sanjyot Vinayak Shenoy, Robert L Moritz, Mukunda Goswami, and Sanjeeva Srivastava

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The PeptideAtlas of a widely cultivated fish Labeo rohita: A resource for the Aquaculture Community., Mehar Un Nissa, Panga Jaipal Reddy, Nevil Pinto, Zhi Sun, Biplab Ghosh, Robert L Moritz, Mukunda Goswami, and Sanjeeva Srivastava

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mHealth-community health worker telemedicine intervention for surgical site infection diagnosis: a prospective study among women delivering via caesarean section in rural Rwanda., Theoneste Nkurunziza, Wendy Williams, Fredrick Kateera, Robert Riviello, Anne Niyigena, Elizabeth Miranda, Laban Bikorimana, Jonathan Nkurunziza, Lotta Velin, Andrea S Goodman, Alex Matousek, Stefanie J Klug, Erick Gaju, and Bethany L Hedt-Gauthier

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Leading with self-empathy: Self-empathy can help leaders find meaning and purpose during difficult times, Stephanie Nolan

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Addition of Allograft and Acromioclavicular Cerclage Improves Outcomes of Arthroscopic-Assisted Reconstruction of Acromioclavicular Separation With a Single Coracoclavicular Tunnel., Matthew P Noyes, Pablo Narbona, Paul C Brady, David P Huberty, Christopher R Adams, Javier Ardebol, and Patrick J Denard

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Anterior vs Posterior Approach in Multilevel Cervical Spondylotic Myelopathy: A Nationwide Propensity-Matched Analysis of Complications, Outcomes, and Narcotic Use., Ravi S Nunna, Syed Khalid, Ryan G Chiu, Rown Parola, Richard G Fessler, Owoicho Adogwa, and Ankit I Mehta

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The complete sequence of a human genome., Sergey Nurk, Sergey Koren, Arang Rhie, Mikko Rautiainen, Andrey V Bzikadze, Alla Mikheenko, Mitchell R Vollger, Nicolas Altemose, Lev Uralsky, Ariel Gershman, Sergey Aganezov, Savannah J Hoyt, Mark Diekhans, Glennis A Logsdon, Michael Alonge, Stylianos E Antonarakis, Matthew Borchers, Gerard G Bouffard, Shelise Y Brooks, Gina V Caldas, Nae-Chyun Chen, Haoyu Cheng, Chen-Shan Chin, William Chow, Leonardo G de Lima, Philip C Dishuck, Richard Durbin, Tatiana Dvorkina, Ian T Fiddes, Giulio Formenti, Robert S Fulton, Arkarachai Fungtammasan, Erik Garrison, Patrick G S Grady, Tina A Graves-Lindsay, Ira M Hall, Nancy F Hansen, Gabrielle A Hartley, Marina Haukness, Kerstin Howe, Michael W Hunkapiller, Chirag Jain, Miten Jain, Erich D Jarvis, Peter Kerpedjiev, Melanie Kirsche, Mikhail Kolmogorov, Jonas Korlach, Milinn Kremitzki, Heng Li, Valerie V Maduro, Tobias Marschall, Ann M McCartney, Jennifer McDaniel, Danny E Miller, James C Mullikin, Eugene W Myers, Nathan D Olson, Benedict Paten, Paul Peluso, Pavel A Pevzner, David Porubsky, Tamara Potapova, Evgeny I Rogaev, Jeffrey A Rosenfeld, Steven L Salzberg, Valerie A Schneider, Fritz J Sedlazeck, Kishwar Shafin, Colin J Shew, Alaina Shumate, Ying Sims, Arian F A Smit, Daniela C Soto, Ivan Sović, Jessica Storer, Aaron Streets, Beth A Sullivan, Françoise Thibaud-Nissen, James Torrance, Justin Wagner, Brian P Walenz, Aaron Wenger, Jonathan M D Wood, Chunlin Xiao, Stephanie M Yan, Alice C Young, Samantha Zarate, Urvashi Surti, Rajiv C McCoy, Megan Y Dennis, Ivan A Alexandrov, Jennifer L Gerton, Rachel J O'Neill, Winston Timp, Justin M Zook, Michael C Schatz, Evan E Eichler, Karen H Miga, and Adam M Phillippy

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Safety and antitumor activity of dostarlimab in patients with advanced or recurrent DNA mismatch repair deficient/microsatellite instability-high (dMMR/MSI-H) or proficient/stable (MMRp/MSS) endometrial cancer: interim results from GARNET-a phase I, single-arm study., Ana Oaknin, Lucy Gilbert, Anna V Tinker, Jubilee Brown, Cara Mathews, Joshua Press, Renaud Sabatier, David M O'Malley, Vanessa Samouelian, Valentina Boni, Linda Duska, Sharad Ghamande, Prafull Ghatage, Rebecca Kristeleit, Charles Leath Iii, Wei Guo, Ellie Im, Sybil Zildjian, Xinwei Han, Tao Duan, Jennifer Veneris, and Bhavana Pothuri

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Prospective Cohort Study of Psoriatic Arthritis Risk in Patients With Psoriasis in a Real-World Psoriasis Registry., Alexis Ogdie, Ryan W Harrison, Robert R McLean, Tin-Chi Lin, Mark Lebwohl, Bruce E Strober, Joe Zhuo, Vardhaman Patel, and Philip J Mease

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Challenges in the Diagnosis and Assessment of Psoriatic Arthritis., Alexis Ogdie, Christine A Lindsay, Philip Mease, Kristina Callis Duffin, Cheryl F Rosen, and Stefan Siebert

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Surgeon feedback to decrease opioid prescriptions after pediatric appendectomy., Kristin Ohe, Edward Hagen, Amber May, Mansen Wang, and Robert Weinsheimer

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Advancing Care and Outcomes for African American Patients With Multiple Sclerosis., Annette F Okai, Annette M Howard, Mitzi J Williams, Justine Brink, Chiayi Chen, tamela stuchiner, Elizabeth Baraban, Grace Jeong, and Stanley Cohan

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A Propensity-Matched Comparison of the Perioperative Outcomes Between Single-Port and Multi-Port Robotic Assisted Partial Nephrectomy: A Report from the Single Port Advanced Research Consortium (SPARC)., Kennedy E Okhawere, Alp Tuna Beksac, Michael P Wilson, Talia G Korn, Kirolos N Meilika, Robert Harrison, Luca Morgantini, Mutahar Ahmed, Reza Mehrazin, Ronney Abaza, Daniel D Eun, Akshay Bhandari, Ashok K Hemal, James R Porter, Michael D Stifelman, Jihad Kaouk, Simone Crivellaro, and Ketan K Badani

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A comparison of outcomes between transperitoneal and retroperitoneal robotic assisted partial nephrectomy in patients with completely endophytic kidney tumors., Kennedy E Okhawere, Jordan Miller Rich, Burak Ucpinar, Alp Tuna Beksac, Indu Saini, Anthony Deluxe, Laura Zuluaga, Daniel D Eun, Akshay Bhandari, Ashok K Hemal, James Porter, Ronney Abaza, Ahmed Mansour, Michael D Stifelman, Simone Crivellaro, Phillip M Pierorazio, Osama Zaytoun, and Ketan K Badani

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Dimethyl Fumarate Delays Multiple Sclerosis in Radiologically Isolated Syndrome., Darin T Okuda, Orhun Kantarci, Christine Lebrun-Frénay, Maria Pia Sormani, Christina J Azevedo, Francesca Bovis, Le H Hua, Lilyana Amezcua, Ellen M Mowry, Christophe Hotermans, Jason Mendoza, John S Walsh, Christian von Hehn, Wendy S Vargas, Stacy Donlon, Robert T Naismith, Annette Okai, Gabriel Pardo, Pavle Repovic, Olaf Stüve, Aksel Siva, and Daniel Pelletier

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Minimally invasive pericranial flap harvest through a supraorbital eyebrow craniotomy: Technical note in salvage skull base reconstruction., Madeline G Olson, Michael B Avery, Shauna Javaherian, Walavan Sivakumar, Daniel F Kelly, Chester Griffiths, and Garni Barkhoudarian

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Repeat Revascularization Post Coronary Artery Bypass Grafting: Comparing Minimally Invasive and Traditional Sternotomy Techniques in 1468 Cases., Peter Olson, Michael Cinelli, Hamfreth S Rahming, Thomas Vazzana, Jonathan Spagnola, Emad Barsoum, Marc Assaad, Frank Tamburrino, and James Lafferty

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The 2022 Report on the Human Proteome from the HUPO Human Proteome Project., Gilbert S Omenn, Lydie Lane, Christopher M Overall, Charles Pineau, Nicolle H Packer, Ileana M Cristea, Cecilia Lindskog, Susan T Weintraub, Sandra Orchard, Michael H A Roehrl, Edouard Nice, Siqi Liu, Nuno Bandeira, Yu-Ju Chen, Tiannan Guo, Ruedi Aebersold, Robert L Moritz, and Eric W Deutsch

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Personal Dense Dynamic Data Clouds Connect Systems Biomedicine to Scientific Wellness., Gilbert S Omenn, Andrew T Magis, Nathan D Price, and Leroy Hood

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IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer., Li-Teng Ong, Wee Chyan Lee, Shijun Ma, Gokce Oguz, Zhitong Niu, Yi Bao, Mubaraka Yusuf, Puay Leng Lee, Jian Yuan Goh, Panpan Wang, Kylie Su Mei Yong, Qingfeng Chen, Wenyu Wang, Adaikalavan Ramasamy, Dave Hoon, Henrik J Ditzel, Ern Yu Tan, Soo Chin Lee, and Qiang Yu

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A Case of Brachial Lymph Node Recurrences after the Resection of Locally Advanced Breast Cancer., Kayono Onishi, Rurina Watanuki, Takamichi Yokoe, Tsuguo Iwatani, Chisako Yamauchi, and Tatsuya Onishi

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Cerebral blood flow dynamics before, during, and after seizures from epilepsy and the periictal state., Kalarickal Oommen and Jonathan Kopel

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Effect of tofacitinib on dactylitis and patient-reported outcomes in patients with active psoriatic arthritis: post-hoc analysis of phase III studies., Ana-Maria Orbai, Philip J Mease, Philip S Helliwell, Oliver FitzGerald, Dona L Fleishaker, Rajiv Mundayat, and Pamela Young

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Salpingo-oophorectomy or surveillance for ovarian endometrioma in asymptomatic premenopausal women: a cost-effectiveness analysis., Megan S Orlando, Lauren A Cadish, Jonathan P Shepherd, Tommaso Falcone, Olivia H Chang, and Rosanne M Kho

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ASO Author Reflections: Breast-Conserving Therapy: A Safe Option in Young Patients with Early-Stage Breast Cancer., Javier I Orozco, Crystal E Fancher, and Janie Grumley

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ASO Visual Abstract: Machine Learning-Based Epigenetic Classifiers for Axillary Staging of Patients with ER-Positive Early-Stage Breast Cancer., Javier I J Orozco, Julie Le, Miquel Ensenyat-Mendez, Jennifer L Baker, Joanne Weidhaas, Alexandra Klomhaus, Diego M Marzese, and Maggie L DiNome

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ASO Visual Abstract: Impact of Locoregional Treatment on Survival in Young Patients with Early-Stage Breast Cancer Undergoing Upfront Surgery., Javier I Orozco, Jennifer Keller, Shu-Ching Chang, Crystal E Fancher, and Janie Grumley

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Impact of Locoregional Treatment on Survival in Young Patients with Early-Stage Breast Cancer undergoing Upfront Surgery., Javier I Orozco, Jennifer Keller, Shu-Ching Chang, Crystal E Fancher, and Janie Grumley

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ASO Author Reflections: Molecular Signatures May Render Surgical Staging of the Axilla Obsolete., Javier I Orozco, Julie Le, Jennifer L Baker, Diego M Marzese, and Maggie L DiNome

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Machine Learning-Based Epigenetic Classifiers for Axillary Staging of Patients with ER-Positive Early-Stage Breast Cancer., Javier I Orozco, Julie Le, Miquel Ensenyat-Mendez, Jennifer L Baker, Joanne Weidhaas, Alexandra Klomhaus, Diego M Marzese, and Maggie L DiNome

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The Role of Parenteral Dantrolene in the Contemporary Management of Cerebral Vasospasm in Aneurysmal Subarachnoid Hemorrhage: A Systematic Review., Michael Ortiz, Ravi S Nunna, Kaushik Ravipati, Angela Tran, Adnan I Qureshi, and Farhan Siddiq

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Safety and efficiency of percutaneous coronary intervention using a standardised optical coherence tomography workflow., Eric A Osborn, Michael Johnson, Aziz Maksoud, Daniel Spoon, Frank J Zidar, Ethan C Korngold, Jana Buccola, Hector Garcia Cabrera, Richard J Rapoza, Nick E J West, and Judah Rauch

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ToPP: Tumor online prognostic analysis platform for prognostic feature selection and clinical patient subgroup selection., Jian Ouyang, Guangrong Qin, Zhenhao Liu, Xingxing Jian, Tieliu Shi, and Lu Xie

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Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial., Sabrina Paganoni, Suzanne Hendrix, Samuel P Dickson, Newman Knowlton, James D Berry, Michael Elliott, Samuel Maiser, Chafic Karam, James B Caress, Margaret Ayo Owegi, Adam Quick, James Wymer, Stephen A Goutman, Daragh Heitzman, Terry D Heiman-Patterson, Carlayne Jackson, Colin Quinn, Jeffrey D Rothstein, Edward J Kasarskis, Jonathan Katz, Liberty Jenkins, Shafeeq S Ladha, Timothy M Miller, Stephen N Scelsa, Tuan H Vu, Christina Fournier, Kristin M Johnson, Andrea Swenson, Namita Goyal, Gary L Pattee, Suma Babu, Marianne Chase, Derek Dagostino, Meghan Hall, Gale Kittle, Mathew Eydinov, Joseph Ostrow, Lindsay Pothier, Rebecca Randall, Jeremy M Shefner, Alexander V Sherman, Eric Tustison, Prasha Vigneswaran, Hong Yu, Joshua Cohen, Justin Klee, Rudolph Tanzi, Walter Gilbert, Patrick Yeramian, and Merit Cudkowicz

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The Human Tumor Atlas Network's beginning steps toward the future of collaborative multi-omic discovery., David B Page

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Brain radiotherapy, tremelimumab-mediated CTLA-4-directed blockade +/- trastuzumab in patients with breast cancer brain metastases., David B Page, Kathryn Beal, Stefanie N Linch, Kateri Spinelli, Micaela Rodine, Darragh Halpenny, Shanu Modi, Sujata Patil, Robert J Young, Thomas Kaley, Taha Merghoub, David Redmond, Phillip Wong, Christopher A Barker, Adi Diab, Larry Norton, and Heather L McArthur

Applications of statistical regression to improve the TIL score and other immune-based biomarkers in breast cancer, DB Page

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Zandelisib with continuous or intermittent dosing as monotherapy or in combination with rituximab in patients with relapsed or refractory B-cell malignancy: a multicentre, first-in-patient, dose-escalation and dose-expansion, phase 1b trial., John M Pagel, Jacob D Soumerai, Nishitha Reddy, Deepa Jagadeesh, Anastasios Stathis, Adam Asch, Huda Salman, Vaishalee P Kenkre, Alexia Iasonos, Judith Llorin-Sangalang, Joanne Li, and Andrew D Zelenetz

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Inhaled Sargramostim (Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor) for COVID-19-Associated Acute Hypoxemia: Results of the Phase 2, Randomized, Open-Label Trial (iLeukPulm)., Robert Paine, Robert Chasse, E Scott Halstead, Jay Nfonoyim, David J Park, Timothy E. Byun, Bela Patel, Guido Molina-Pallete, Estelle S Harris, Fiona Garner, Lorinda Simms, Sanjeev Ahuja, John L McManus, and Debasish F Roychowdhury

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Molecular alterations associated with improved outcome in patients with glioblastoma treated with Tumor-Treating Fields., Manjari Pandey, Joanne Xiu, Sandeep Mittal, Jia Zeng, Michelle Saul, Santosh Kesari, Amir Azadi, Herbert Newton, Karina Deniz, Katherine Ladner, Ashley Sumrall, W Michael Korn, and Emil Lou

172P Phase I study of JTX-8064, a LILRB2 (ILT4) inhibitor, as monotherapy and combination with pimivalimab (pimi), a PD-1 inhibitor (PD-1i), in patients (pts) with advanced solid tumors, K Papadopoulos, Rachel Sanborn, and See all authors in comments

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Associations between SARS-CoV-2 variants and risk of COVID-19 hospitalization among confirmed cases in Washington State: a retrospective cohort study., Miguel I Paredes, Stephanie M Lunn, Michael Famulare, Lauren A Frisbie, Ian Painter, Roy Burstein, Pavitra Roychoudhury, Hong Xie, Shah A Mohamed Bakhash, Ricardo Perez, Maria Lukes, Sean Ellis, Saraswathi Sathees, Patrick C Mathias, Alexander Greninger, Lea M Starita, Chris D Frazar, Erica Ryke, Weizhi Zhong, Luis Gamboa, Machiko Threlkeld, Jover Lee, Evan McDermot, Melissa Truong, Deborah A Nickerson, Daniel L Bates, Matthew E Hartman, Eric Haugen, Truong N Nguyen, Joshua D Richards, Jacob L Rodriguez, John A Stamatoyannopoulos, Eric Thorland, Geoff Melly, Philip E Dykema, Drew C MacKellar, Hannah K Gray, Avi Singh, JohnAric M Peterson, Denny Russell, Laura Marcela Torres, Scott Lindquist, Trevor Bedford, Krisandra J Allen, and Hanna N Oltean

1296 ­Radiomics-based multi-modal prediction of treatment response to PD-1/PD-L1 immune checkpoint inhibitor (ICI) therapy in stage IV non-small cell lung carcinoma (mNSCLC), Ravi Parikh, Brendan Curti, Roshanthi Weerasinghe, and See all authors in comments

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Chemoradiation therapy alters the PD-L1 score in locoregional recurrent squamous cell carcinomas of the head and neck., Brian J Park, Austin K Mattox, Daniel Clayburgh, Mihir Patel, R Bryan Bell, Bevan Yueh, Rom Leidner, Hong Xiao, Marcus Couey, Shiting Li, Tingting Qin, Maureen A Sartor, Belinda Cairns, Tracy MacDonough, Kyle Halliwill, Daniel Deschler, Derrick T Lin, William C Faquin, Peter M Sadow, and Sara I Pai

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An inactivated multivalent influenza A virus vaccine is broadly protective in mice and ferrets., Jaekeun Park, Sharon L Fong Legaspi, Louis M Schwartzman, Sebastian M Gygli, Zhong-Mei Sheng, Ashley D Freeman, Lex M Matthews, Yongli Xiao, Mitchell D Ramuta, Natalia A Batchenkova, Li Qi, Luz Angela Rosas, Stephanie L Williams, Kelsey Scherler, Monica Gouzoulis, Ian Bellayr, David M Morens, Kathie-Anne Walters, Matthew J Memoli, John C Kash, and Jeffery K Taubenberger

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A single-cell based precision medicine approach using glioblastoma patient-specific models., James H Park, Abdullah H Feroze, Samuel N Emerson, Anca B Mihalas, C Dirk Keene, Patrick J Cimino, Adrian Lopez Garcia de Lomana, Kavya Kannan, Wei-Ju Wu, Serdar Turkarslan, Nitin S Baliga, and Anoop P Patel

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Examination of the Economic Burden of Frailty in Patients With Adult Spinal Deformity Undergoing Surgical Intervention., Peter G Passias, Waleed Ahmad, Nicholas Kummer, Renaud Lafage, Virginie Lafage, Khaled Kebaish, Alan Daniels, Eric Klineberg, Alex Soroceanu, Jeffrey Gum, Breton Line, Robert A Hart, Douglas Burton, Robert Eastlack, Amit Jain, Justin S Smith, Christopher P Ames, Christopher Shaffrey, Frank Schwab, Richard Hostin, and Shay Bess

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Development of Risk Stratification Predictive Models for Cervical Deformity Surgery., Peter G Passias, Waleed Ahmad, Cheongeun Oh, Bailey Imbo, Sara Naessig, Katherine Pierce, Virginie Lafage, Renaud Lafage, D Kojo Hamilton, Themistocles S Protopsaltis, Eric O Klineberg, Jeffrey Gum, Andrew J Schoenfeld, Breton Line, Robert A Hart, Douglas C Burton, Shay Bess, Frank J Schwab, Justin S Smith, Christopher I Shaffrey, Christopher P Ames, and International Spine Study Group

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Changes in health-related quality of life measures associated with degree of proximal junctional kyphosis., Peter G Passias, Nicholas J Frangella, Tyler K Williamson, Kevin A Moattari, Renaud Lafage, Virginie Lafage, Justin S Smith, Khaled M Kebaish, Douglas C Burton, Robert A Hart, Christopher P Ames, Shay Bess, Christopher I Shaffrey, and Frank J Schwab

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Evolution of Adult Cervical Deformity Surgery Clinical and Radiographic Outcomes Based on a Multicenter Prospective Study: Are Behaviors and Outcomes Changing with Experience?, Peter G Passias, Oscar Krol, Kevin Moattari, Tyler K Williamson, Virginie Lafage, Renaud Lafage, Han Jo Kim, Alan Daniels, Bassel Diebo, Themistocles Protopsaltis, Gregory Mundis, Khaled Kebaish, Alexandra Soroceanu, Justin Scheer, D Kojo Hamilton, Eric Klineberg, Andrew J Schoenfeld, Shaleen Vira, Breton Line, Robert Hart, Douglas C Burton, Frank A Schwab, Christopher Shaffrey, Shay Bess, Justin S Smith, Christopher P Ames, and International Spine Study Group

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The Benefit of Addressing Malalignment In Revision Surgery for Proximal Junctional Kyphosis Following ASD Surgery., Peter G Passias, Oscar Krol, Tyler K Williamson, Virginie Lafage, Renaud Lafage, Justin S Smith, Breton Line, Shaleen Vira, Shaina Lipa, Alan Daniels, Bassel Diebo, Andrew Schoenfeld, Jeffrey Gum, Khaled Kebaish, Paul Park, Gregory Mundis, Richard Hostin, Manush Gupta, Robert Eastlack, Neel Anand, Christopher Ames, Robert A Hart, Douglas Burton, Frank J Schwab, Christopher Shaffrey, Eric Klineberg, and Shay Bess

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Improvements in Outcomes and Cost after Adult Spinal Deformity Corrective Surgery between 2008 and 2019., Peter G Passias, Nicholas Kummer, Bailey Imbo, Virginie Lafage, Renaud Lafage, Justin S Smith, Breton Line, Shaleen Vira, Andrew J Schoenfeld, Jeffrey L Gum, Alan H Daniels, Eric O Klineberg, Munish C Gupta, Khaled M Kebaish, Amit Jain, Brian J Neuman, Dean Chou, Leah Y Carreon, Robert A Hart, Douglas C Burton, Christopher I Shaffrey, Christopher P Ames, Frank J Schwab, Richard A Hostin, Shay Bess, and International Spine Study Group

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The Additional Economic Burden of Frailty in Adult Cervical Deformity Patients Undergoing Surgical Intervention., Peter G Passias, Nicholas Kummer, Tyler K Williamson, Waleed Ahmad, Jordan Lebovic, Virginie Lafage, Renaud Lafage, Han Jo Kim, Alan H Daniels, Jeffrey L Gum, Bassel G Diebo, Munish C Gupta, Alexandra Soroceanu, Justin K Scheer, D Kojo Hamilton, Eric O Klineberg, Breton Line, Andrew J Schoenfeld, Robert A Hart, Douglas C Burton, Robert K Eastlack, Gregory M Mundis, Praveen Mummaneni, Dean Chou, Paul Park, Frank J Schwab, Christopher I Shaffrey, Shay Bess, Christopher P Ames, Justin S Smith, and International Spine Study Group

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Highest Achievable Outcomes for Patients Undergoing Cervical Deformity Corrective Surgery by Frailty., Peter G Passias, Nicholas Kummer, Tyler K Williamson, Kevin Moattari, Virginie Lafage, Renaud Lafage, Han Jo Kim, Alan H Daniels, Jeffrey L Gum, Bassel G Diebo, Themistocles S Protopsaltis, Gregory M Mundis, Robert K Eastlack, Alexandra Soroceanu, Justin K Scheer, D Kojo Hamilton, Eric O Klineberg, Breton Line, Robert A Hart, Douglas C Burton, Praveen Mummaneni, Dean Chou, Paul Park, Frank J Schwab, Christopher I Shaffrey, Shay Bess, Christopher P Ames, and Justin S Smith

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Establishment of an Individualized Distal Junctional Kyphosis Risk Index following the Surgical Treatment of Adult Cervical Deformities., Peter G Passias, Sara Naessig, Navraj Sagoo, Lara Passfall, Waleed Ahmad, Renaud Lafage, Virginie Lafage, Shaleen Vira, Andrew J Schoenfeld, Cheongeun Oh, Themistocles Protopsaltis, Han Jo Kim, Alan Daniels, Robert A Hart, Douglas Burton, Eric O Klineberg, Shay Bess, Frank Schwab, Christopher Shaffrey, Christopher P Ames, Justin S Smith, and International Spine Study Group

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Pelvic Non-Response Following Treatment of Adult Spinal Deformity: Influence of Realignment Strategies on Occurrence., Peter G Passias, Katherine E Pierce, Tyler K Williamson, Oscar Krol, Renaud Lafage, Virginie Lafage, Andrew J Schoenfeld, Themistocles S Protopsaltis, Shaleen Vira, Breton Line, Bassel G Diebo, Christopher P Ames, Han Jo Kim, Justin S Smith, Dean Chou, Alan H Daniels, Jeffrey L Gum, Christopher I Shaffrey, Douglas C Burton, Michael P Kelly, Eric O Klineberg, Robert A Hart, Shay Bess, Frank J Schwab, and Munish C Gupta

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Predictive Analytics for Determining Extended Operative Time in Corrective Adult Spinal Deformity Surgery., Peter G Passias, Gregory W Poorman, Dennis Vasquez-Montes, Nicholas Kummer, Gregory Mundis, Neel Anand, Samantha R Horn, Frank A Segreto, Lara Passfall, Oscar Krol, Bassel Diebo, Doug Burton, Aaron Buckland, Michael Gerling, Alex Soroceanu, Robert Eastlack, D Kojo Hamilton, Robert A Hart, Frank Schwab, Virginie Lafage, Christopher Shaffrey, Daniel Sciubba, Shay Bess, Christopher Ames, Eric Klineberg, and International Spine Study Group

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Is frailty responsive to surgical correction of adult spinal deformity? An investigation of sagittal re-alignment and frailty component drivers of postoperative frailty status., Peter G Passias, Frank A Segreto, Kevin A Moattari, Renaud Lafage, Justin S Smith, Breton G Line, Robert K Eastlack, Douglas C Burton, Robert A Hart, Shay Bess, Christopher I Shaffrey, Christopher P Ames, Virginie Lafage, and International Spine Study Group

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Posterior Ischemic Optic Neuropathy Because of Hematologic Malignancy., Ankush U Patel, Uresh S Patel, and Eugene F May

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Effect of a Community Health Worker Intervention on Acute Care Use, Advance Care Planning, and Patient-Reported Outcomes Among Adults With Advanced Stages of Cancer: A Randomized Clinical Trial., Manali I Patel, Kristopher Kapphahn, Marilyn Dewland, Veronica Aguilar, Blanca Sanchez, Etsegenet Sisay, Ariana Murillo, Kim Smith, and David J Park

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#754 A PHASE 1/2 STUDY OF ASP1570 IN PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC SOLID TUMORS WHO HAVE PROGRESSED ON, OR ARE INELIGIBLE FOR, ALL AVAILABLE STANDARD THERAPIES, Manish Patel, David J Park, and See full list of authors in comments

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A PHASE 1/2 STUDY OF ASP1570 IN PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC SOLID TUMORS WHO HAVE PROGRESSED ON, OR ARE INELIGIBLE FOR, ALL AVAILABLE STANDARD THERAPIES, Manish Patel, David J Park, and See full list of authors in comments

A PHASE 1/2 STUDY OF ASP1570 IN PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC SOLID TUMORS WHO HAVE PROGRESSED ON, OR ARE INELIGIBLE FOR, ALL AVAILABLE STANDARD THERAPIES, Manish Patel, David Park, and See all authors in comments

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Clinical and radiographic benefits of skipping C7 instrumentation in posterior cervicothoracic fusion: a retrospective analysis., Saavan Patel, Morteza Sadeh, Matthew K Tobin, Nauman S Chaudhry, C Gragnaniello, and Sergey Neckrysh

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Factors associated with poor outcomes among COVID-19 patients with gastrointestinal symptoms., Nikita Patil, Pankush Kalgotra, Suneha Sundaram, Stephanie Melquist, Sravanthi Parasa, Madhav Desai, and Prateek Sharma

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MTAP loss: a possible therapeutic approach for glioblastoma., C Pawan K Patro, Nupur Biswas, Sandeep C Pingle, Feng Lin, Misa Anekoji, Lawrence D Jones, Santosh Kesari, Feng Wang, and Shashaanka Ashili

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Reconsidering the in vivo functions of Clostridial Stickland amino acid fermentations., Aidan Pavao, Madeline Graham, Mario L Arrieta-Ortiz, Selva Rupa Christinal Immanuel, Nitin S Baliga, and Lynn Bry

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Genetic polymorphisms and correlation with treatment induced cardiotoxicity and prognosis in breast cancer patients., Parvin Peddi, Peter A Fasching, Duan Liu, Emmanuel Quinaux, Nicholas J Robert, Vicente Valero, John Crown, Carla Falkson, Adam Brufsky, Julie M Cunningham, Richard M Weinshilboum, Tadeusz Pienkowski, Wolfgang Eiermann, Miguel Martín, Valerie Bee, Xiaoyan Wang, Liewei Wang, Eric Yang, Dennis J Slamon, and Sara A Hurvitz

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Why arch vessel ligation is unethical for thoracoabdominal normothermic regional perfusion., Harry Peled and James L Bernat

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Normothermic Regional Perfusion Requires Careful Ethical Analysis Before Adoption Into Donation After Circulatory Determination of Death., Harry Peled, Sajen Mathews, David Rhodes, and James L Bernat

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Reducing Eating Disorder Risk Among Male Athletes: A Randomized Controlled Trial Investigating the Male Athlete Body Project., Hayley Perelman, Natalie Schwartz, Jennifer Yeoward-Dodson, Isabel C Quiñones, Matthew F Murray, Elizabeth N Dougherty, Raven Townsel, Jessyca Arthur-Cameselle, and Alissa A Haedt-Matt