Methods and compositions for inducing an immune response to EGFRvIII

Authors

Peter M. Lauer
Keith Bahjat

Document Type

Patent

Publication Date

8-6-2013

Abstract

The present invention relates to methods of inducing a T-cell response against a EGFRvIII in a subject. These method comprise administering to a subject a composition which expresses at least one immunogenic polypeptide, the amino acid sequence of which comprise a plurality of EGFRvIII polypeptide sequences, the sequence of which each comprise EEKKGNYV (SEQ ID NO: 3), and/or administering the polypeptide itself.

Location

United States

Comments

Patent Number: 9,200,057

Assignee

ADURO BIOTECH, INC. (Berkeley, CA); PROVIDENCE HEALTH & SERVICES--OREGON (Portland, OR)

Family ID

46084412

Serial Number

14/952,470

Tech ID

10-03-INV