Epigenetic silencing of cyclooxygenase-2 affects clinical outcome in gastric cancer

Authors

Dave S B Hoon, Department of Translational Molecular Medicine, John Wayne Cancer Institute (JWCI) at Providence Saint John's Health Center, Santa Monica, CA 90404 USA.Follow
Michiel de Maat

Document Type

Patent

Publication Date

6-13-2008

Abstract

The present invention discloses methods of using the methylation status of the COX-2 gene promoter region as a biomarker for a gastric cancer patient to determine a prognosis and a treatment regimen, and to monitor the progress of a treatment regimen.

Clinical Institute

Cancer

Clinical Institute

Digestive Health

Specialty/Research Institute

Oncology

Specialty/Research Institute

Gastroenterology

Location

United States

Comments

Patent Number: 7,851,161

Assignee

John Wayne Cancer Institute (Santa Monica, CA)

Family ID

40156645

Serial Number

12/139,415

Tech ID

07-JWCI-055