Providence research from Washington locations.

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Submissions from 2024

“New use for Ozempic”, Katherine Tuttle

“Ozempic cuts risk of chronic kidney disease complications, study finds””, Katherine Tuttle

“Ozempic keeps wowing: trial data show benefits for kidney disease”, Katherine Tuttle

“Ozempic reduces risk of serious illness and death in people with diabetes and kidney disease, study finds", Katherine Tuttle

Research Development., Katherine Tuttle

“Semaglutide cuts kidney failure and death in diabetes”, Katherine Tuttle

“Semaglutide significantly improves chronic kidney disease”, Katherine Tuttle

“Success of GLP-1 receptor agonists in kidney disease halts FLOW trial early.”, Katherine Tuttle

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Clinical Characteristics and Histopathology in Adults With Focal Segmental Glomerulosclerosis., Katherine Tuttle, Clint W Abner, Patrick D Walker, Kaijun Wang, Andrew Rava, Jihaeng Heo, and Martin Bunke

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Clinical Characteristics and Histopathology in Adults With Focal Segmental Glomerulosclerosis., Katherine Tuttle, Clint W Abner, Patrick D Walker, Kaijun Wang, Andrew Rava, Jihaeng Heo, and Martin Bunke

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Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic kidney disease: a randomised, controlled, phase 2 trial., Katherine Tuttle, Sibylle J Hauske, Maria Eugenia Canziani, Maria Luiza Caramori, David Cherney, Lisa Cronin, Hiddo J L Heerspink, Christian Hugo, Masaomi Nangaku, Ricardo Correa Rotter, Arnold Silva, Shimoli V Shah, Zhichao Sun, Dorothea Urbach, Dick de Zeeuw, and Peter Rossing

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Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic kidney disease: a randomised, controlled, phase 2 trial., Katherine R Tuttle, Sibylle J Hauske, Maria Eugenia Canziani, Maria Luiza Caramori, David Cherney, Lisa Cronin, Hiddo J L Heerspink, Christian Hugo, Masaomi Nangaku, Ricardo Correa Rotter, Arnold Silva, Shimoli V Shah, Zhichao Sun, Dorothea Urbach, Dick de Zeeuw, Peter Rossing, and ASi in CKD group

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Anal Condyloma and Human Papillomavirus: Recognition, Treatment, and Prevention., Kenley R Unruh and Debra D Lai

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Left atrial to coronary sinus shunting for treatment of heart failure with mildly reduced or preserved ejection fraction: The ALT FLOW Early Feasibility Study 1-year results., Marcus A Urey, Benjamin Hibbert, Ulrich Jorde, Peter Eckman, Trevor Simard, Marino Labinaz, Babak Nazer, Mark Wiley, Bhanu Gupta, Andrew Sauer, Hirak Shah, Paul Sorajja, Andres M Pineda, Emil Missov, Ehtisham Mahmud, Rami Kahwash, Scott Lilly, Azeem Latib, Sandhya Murthy, Neil Fam, Santiago Garcia, Eugene S Chung, Liviu Klein, Richard Cheng, Brian A Houston, Nicholas S Amoroso, Lee Chang, Sameer Gafoor, Sunit-Preet Chaudhry, James Hermiller, Jonathan G Schwartz, Lillian Aldaia, Konstantinos Koulogiannis, William A Gray, and Firas Zahr

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Origin of biogeographically distinct ecotypes during laboratory evolution., Jacob J Valenzuela, Selva Rupa Christinal Immanuel, James Wilson, Serdar Turkarslan, Maryann Ruiz, Sean M Gibbons, Kristopher A Hunt, Nejc Stopnisek, Manfred Auer, Marcin Zemla, David A Stahl, and Nitin Baliga

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Combination therapy for kidney disease in people with diabetes mellitus., Daniël H van Raalte, Petter Bjornstad, David Z I Cherney, Ian H de Boer, Paola Fioretto, Daniel Gordin, Frederik Persson, Sylvia E Rosas, Peter Rossing, Jennifer A Schaub, Katherine Tuttle, Sushrut S Waikar, and Hiddo J L Heerspink

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The Zea mays PeptideAtlas: A New Maize Community Resource, Klaas J van Wijk, Tami Leppert, Zhi Sun, Isabell Guzchenko, Erica Debley, Georgia Sauermann, Pratyush Routray, Luis Mendoza, Qi Sun, and Eric W Deutsch

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Detection of the Arabidopsis Proteome and Its Post-translational Modifications and the Nature of the Unobserved (Dark) Proteome in PeptideAtlas, Klaas J van Wijk, Tami Leppert, Zhi Sun, Alyssa Kearly, Margaret Li, Luis Mendoza, Isabell Guzchenko, Erica Debley, Georgia Sauermann, Pratyush Routray, Sagunya Malhotra, Andrew Nelson, Qi Sun, and Eric W Deutsch

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A real-world study of treatment sequences and second-line clinical outcomes in patients with HER2-positive metastatic breast cancer in US community practice., Della Varghese, Giovanna I Cruz, Colden Johanson, Liz Toland, Miguel Miranda, Eleanor C Faherty, David Harland, and Henry G Kaplan

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Management of Neurologic Complications in Patients with Brain and Spine Tumors., Alipi V Bonm and Lynne P Taylor

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Impact of Prior Biologic or Janus Kinase Inhibitor Therapy on Efficacy and Safety of Etrasimod in the ELEVATE UC 52 and ELEVATE UC 12 Trials., Séverine Vermeire, Bruce E Sands, Laurent Peyrin-Biroulet, Geert R D'Haens, Julian Panés, Andres J Yarur, Douglas C Wolf, Timothy Ritter, Stefan Schreiber, John C Woolcott, Irene Modesto, Michael Keating, Kevin Shan, Joseph Wu, Michael Chiorean, Filip Baert, Marla C Dubinsky, Martina Goetsch, Silvio Danese, and Brian G Feagan

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The Postoperative Airway Compromise Score-First Steps to Developing a Postoperative Tool for the Assessment of Upper Airway-Related Complications Following Anterior Cervical Spine Surgery., Alexander von Glinski, Clifford A Pierre, Christopher Elia, Basem Ishak, Periklis Godolias, Ronen Blecher, Joseph R Detorri, Daniel C Norvell, Luke Jouppi, Julius Gerstmeyer, Steven A Deem, J Blake Golden, Thomas A Schildhauer, Rod J Oskouian, and Jens R Chapman

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Historical Perspectives on the Evolution of Spino-Pelvic Fixation and its Implications on Clinical Care A Narrative Review., Alexander von Glinski, Emre Yilmaz, Periklis Godolias, Lorin Benneker, F C Oner, Frank Kandziora, Gregory Schroeder, Klaus Schnake, Marcel Dvorak, Shanmuganathan Rajasekaran, Mohammad El-Sharkawi, Alexander Vaccaro, Richard Bransford, Thomas A Schildhauer, and Jens R Chapman

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Ambulatory Robotic Colectomy: Factors Affecting and Affected by Postoperative Opioid Use., Michael M Vu, Jace J Franko, Anna Buzadzhi, Beau Prey, Maksim Rusev, Marta M Lavery, and Laila Rashidi

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Incidence and Presenting Characteristics of Angiosarcoma in the US, 2001-2020., Michael J Wagner, Vinod Ravi, Stephanie K Schaub, Ed Y Kim, Jeremy Sharib, Harveshp Mogal, Min Park, Michaela Tsai, Daniela Duarte-Bateman, Anthony Tufaro, Elizabeth T Loggers, Lee D Cranmer, Bonny Chau, Michael J Hassett, Juneko Grilley-Olson, and Kelly G Paulson

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Comparison of Real-World On-Label Treatment Persistence in Patients with Psoriatic Arthritis Receiving Guselkumab Versus Subcutaneous Tumor Necrosis Factor Inhibitors., Jessica A Walsh, Iris Lin, Ruizhi Zhao, Natalie J Shiff, Laura Morrison, Bruno Emond, Louise H Yu, Samuel Schwartzbein, Patrick Lefebvre, Dominic Pilon, Soumya D Chakravarty, and Philip Mease

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Association of COVID-19 Versus COVID-19 Vaccination With Kidney Function and Disease Activity in Primary Glomerular Disease: A Report of the Cure Glomerulonephropathy Study., Chia-Shi Wang, Dorey A Glenn, Margaret Helmuth, Abigail R Smith, Andrew S Bomback, Pietro A Canetta, Gaia M Coppock, Myda Khalid, Katherine Tuttle, Raed Bou-Matar, Larry A Greenbaum, Bruce M Robinson, Lawrence B Holzman, William E Smoyer, Michelle N Rheault, Debbie Gipson, Laura H Mariani, and Cure Glomerulonephropathy (CureGN) Study Consortium

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Global Spine Journal and Global Spine Congress., Jeffrey C Wang, Jens R Chapman, and Karsten Wiechert

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Comparative Effectiveness of Bimekizumab and Guselkumab in Patients with Psoriatic Arthritis at 52 Weeks Assessed Using a Matching-Adjusted Indirect Comparison., Richard B Warren, Iain B McInnes, Peter Nash, Jean-Marie Grouin, Nikos Lyris, Damon Willems, Vanessa Taieb, Jason Eells, and Philip Mease

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Critical lessons from a pragmatic randomized trial of home-based COVID-19 testing in rural Native American and Latino communities., Eliza Webber, Sonia Bishop, Paul K Drain, Virgil Dupuis, Lorenzo Garza, Charlie Gregor, Laurie Hassell, Geno Ibarra, Larry Kessler, Linda Ko, Alison Lambert, Victoria Lyon, Carly Rowe, Michael Singleton, Matthew Thompson, Teresa Warne, Wendy Westbroek, and Alexandra Adams

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Machine learning to understand risks for severe COVID-19 outcomes: a retrospective cohort study of immune-mediated inflammatory diseases, immunomodulatory medications, and comorbidities in a large US health-care system., Qi Wei, Philip J Mease, Michael Chiorean, Lulu Iles-Shih, Wanessa F Matos, Andrew Baumgartner, Sevda Molani, Yeon Mi Hwang, Basazin Belhu, Alexandra Ralevski, and Jennifer Hadlock

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Understanding Washington State's Low Uptake of Lung Cancer Screening in Two Steps: A Geospatial Analysis of Patient Travel Time and Health Care Availability of Imaging Sites., Allison C Welch, Jed A Gorden, Stephen J Mooney, Candice L Wilshire, and Steven B Zeliadt

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When Will Peer-Review Become A.I.-Review?, Karsten Wiechert, Jeffrey C Wang, and Jens R Chapman

Unhealthy Alcohol Use and Initiation of and Adherence to Pre-Exposure Prophylaxis Among Va Patients: Overall and Among Sexual and Gender Minoritized Patients Veterans, EC Williams, K McGinnis, M Skanderson, EJ Austin, M Bentley, JL Goulet, D Satre, Kara M. Bensley, K Bryant, and EJ Edelman

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Persistent Lower Extremity Compensation for Sagittal Imbalance After Surgical Correction of Complex Adult Spinal Deformity: A Radiographic Analysis of Early Impact., Tyler K Williamson, Pooja Dave, Jamshaid M Mir, Justin S Smith, Renaud Lafage, Breton Line, Bassel G Diebo, Alan H Daniels, Jeffrey L Gum, Themistocles S Protopsaltis, D Kojo Hamilton, Alex Soroceanu, Justin K Scheer, Robert Eastlack, Michael P Kelly, Pierce Nunley, Khaled M Kebaish, Stephen Lewis, Lawrence G Lenke, Richard A Hostin, Munish C Gupta, Han Jo Kim, Christopher P Ames, Robert A Hart, Douglas C Burton, Christopher I Shaffrey, Eric O Klineberg, Frank J Schwab, Virginie Lafage, Dean Chou, Kai-Ming Fu, Shay Bess, Peter G Passias, and International Spine Study Group

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Perspectives on Online Resources for People Experiencing Pain: A Qualitative Study., Marian Wilson, Janet R Katz, Mafe D Chase, Ross J Bindler, Teresa L Rangel, Rebecca A Penders, Pamela S Kohlmeier, and Jamie Lewis

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Medicare Utilization and Cost Trends for CAR T Cell Therapies Across Settings of Care in the Treatment of Diffuse Large B-Cell Lymphoma., James Wu, Armin Ghobadi, Richard Maziarz, Krish Patel, Hil Hsu, Zihao Liu, Caitlin Sheetz, Peter Kardel, and Christine Fu

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Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex., Zhenlin Yang, Amel Mameri, Claudia Cattoglio, Catherine Lachance, Alfredo Jose Florez Ariza, Jie Luo, Jonathan Humbert, Deepthi Sudarshan, Arul Banerjea, Maxime Galloy, Amélie Fradet-Turcotte, Jean-Philippe Lambert, Jeff A Ranish, Jacques Côté, and Eva Nogales

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Hospitalization and help-seeking among first episode psychosis patients., Anna Yee, Sarah Greene, Ashley Weiss, Serena Chaudhry, and Spencer Steadman

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Increasing U.S. Maternal Health Equity Among Immigrant Populations Through Community Engagement., Maryum Zaidi, Heidi Collins Fantasia, Rebecca Penders, Ainat Koren, and Comfort Enah

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Association between class III obesity and overall survival in previously untreated younger patients with acute myeloid leukemia enrolled on SWOG S1203., Michelle Y Zhang, Megan Othus, Kerry McMillen, Harry P Erba, Guillermo Garcia-Manero, John M Pagel, Mohamed L Sorror, and Mary-Elizabeth M Percival

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SpectiCal: m/ z Calibration of MS2 Peptide Spectra Using Known Low Mass Ions, Nathan H Zhang and Eric W Deutsch

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Metaproteomic analysis decodes trophic interactions of microorganisms in the dark ocean., Zihao Zhao, Chie Amano, Thomas Reinthaler, Federico Baltar, Mónica V Orellana, and Gerhard J Herndl

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Substrate uptake patterns shape niche separation in marine prokaryotic microbiome., Zihao Zhao, Chie Amano, Thomas Reinthaler, Monica V Orellana, and Gerhard J Herndl

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Memory Cart: Memory-Making Interventions for Nurses to Enhance the Meaningfulness of End-of-Life Care in the ICU, Grace Zimmerman

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Optimization of a standardized letter of recommendation for faculty who wish to support candidates applying to surgical training programs., Clare Zipf-Sigler, Alisha L Nguyen, Amber Huang, Ryan De Leon, Shannon Helbling, Eliza B Littleton, and Anjali S Kumar

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A new era in the science and care of kidney diseases., Carmine Zoccali, Francesca Mallamaci, Liz Lightstone, Vivek Jha, Carol Pollock, Katherine Tuttle, Peter Kotanko, Andrzej Wiecek, Hans Joachim Anders, Giuseppe Remuzzi, Kamyar Kalantar-Zadeh, Adeera Levin, and Raymond Vanholder

Submissions from 2023

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An Evidence-Based Approach to Orthobiologics for Tendon Disorders., Andre Armando Abadin, Jordan Pearl Orr, Alexander Raphael Lloyd, Phillip Troy Henning, and Adam Pourcho

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Comprehensive Venous Outflow Predicts Functional Outcomes in Patients with Acute Ischemic Stroke Treated by Thrombectomy., G Adusumilli, T D Faizy, S Christensen, M Mlynash, Yince Loh, G W Albers, M G Lansberg, J Fiehler, and J J Heit

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Modifiability of Composite Cardiovascular Risk Associated With Chronic Kidney Disease in Type 2 Diabetes With Finerenone., Rajiv Agarwal, Bertram Pitt, Peter Rossing, Stefan D Anker, Gerasimos Filippatos, Luis M Ruilope, Csaba P Kovesdy, Katherine Tuttle, Muthiah Vaduganathan, Christoph Wanner, Sameer Bansilal, Martin Gebel, Amer Joseph, Robert Lawatscheck, and George L Bakris

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Impact of Finerenone-Induced Albuminuria Reduction on Chronic Kidney Disease Outcomes in Type 2 Diabetes : A Mediation Analysis., Rajiv Agarwal, Wanzhu Tu, Alfredo E Farjat, Youssef M K Farag, Robert Toto, Sanjay Kaul, Robert Lawatscheck, Katja Rohwedder, Luis M Ruilope, Peter Rossing, Bertram Pitt, Gerasimos Filippatos, Stefan D Anker, George L Bakris, FIDELIO-DKD and FIGARO-DKD Investigators, and Katherine Tuttle

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Pertuzumab Plus Trastuzumab in Patients With Endometrial Cancer With, Eugene R Ahn, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Hussein M Ali-Ahmad, John Chan, Michael L Maitland, Sapna R Patel, Zachary Reese, Ani S Balmanoukian, Charles W Drescher, Rui Li, Apostolia M Tsimberidou, Charles A Leath, Raegan O'Lone, Gina N Grantham, Susan Halabi, and Richard L Schilsky

“Intensifying Diabetes Therapies to Achieve Personalized Treatment Goals”, Radica Alicic

Incidence of chronic kidney disease in prediabetes, Radica Alicic, Ken Daratha, Joshua J Neumiller, Katherine Tuttle, and See all authors in comments

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Author Response to "Insulin Dosing Safety in CKD"., Radica Alicic, Joshua J Neumiller, Rodolfo J Galindo, and Katherine Tuttle

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Mechanisms and clinical applications of incretin therapies for diabetes and chronic kidney disease., Radica Alicic, Joshua J Neumiller, and Katherine Tuttle

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Incretin Therapies for Patients with Type 2 Diabetes and Chronic Kidney Disease., Radica Z Alicic and Joshua J Neumiller

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Early recapture of response with tofacitinib 10 mg twice daily in patients with ulcerative colitis in OCTAVE Open following dose reduction or treatment interruption in OCTAVE Sustain., Jessica R Allegretti, Krisztina B Gecse, Michael Chiorean, Marjorie Argollo, Xiang Guo, Nervin Lawendy, Chinyu Su, Rajiv Mundayat, Jerome Paulissen, Leonardo Salese, and Peter M Irving

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Vemurafenib- and Cobimetinib-Associated Drug Reaction With Eosinophilia and Systemic Symptoms in a Patient With Metastatic Melanoma., Miriam Al-Saedy, Salsabeal Al-Saedy, and Chad Rieck

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American Society for Gastrointestinal Endoscopy guideline on management of post-liver transplant biliary strictures: methodology and review of evidence., Stuart K Amateau, Divyanshoo R Kohli, Madhav Desai, Srinath Chinnakotla, M Edwyn Harrison, Jean M Chalhoub, Nayantara Coelho-Prabhu, Sherif E Elhanafi, Nauzer Forbes, Larissa L Fujii-Lau, Richard S Kwon, Jorge D Machicado, Neil B Marya, Swati Pawa, Wenly Ruan, Sunil G Sheth, Nikhil R Thiruvengadam, Nirav C Thosani, Bashar J Qumseya, and ASGE Standards of Practice Committee Chair

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Anti-CD20 monoclonal antibody therapy in postpartum women with neurological conditions., Annika Anderson, William Rowles, Shane Poole, Ayushi Balan, Carolyn Bevan, Rachel Brandstadter, Andrea I Ciplea, Joanna Cooper, Michelle Fabian, Thomas W Hale, Dina Jacobs, Mihir Kakara, Kristen M Krysko, Erin E Longbrake, Jacqueline Marcus, Pavle Repovic, Claire S Riley, Andrew R Romeo, Alice Rutatangwa, Timothy West, Kerstin Hellwig, Sara C LaHue, and Riley Bove

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Team USA injury and illness incidence at the 2022 Beijing Winter Olympic and Paralympic Games., Travis Anderson, Malia G Cali, Stephanie C Clark, Ike Hasley, Emily G Larson, Kayle E Noble-Taylor, David M Robinson, Eric Post, Jonathan T Finnoff, and William M Adams

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Determining the best vertebra for measuring pelvic incidence and spinopelvic parameters in adult spinal deformity patients with transitional anatomy., Fares Ani, Themistocles S Protopsaltis, Yesha Parekh, Khalid Odeh, Renaud Lafage, Justin S Smith, Robert K Eastlack, Lawrence Lenke, Frank Schwab, Gregory M Mundis, Munish C Gupta, Eric O Klineberg, Virginie Lafage, Robert A Hart, Douglas Burton, Christopher P Ames, Christopher I Shaffrey, and Shay Bess

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Identifying barriers to shared decision-making about bariatric surgery in two large health systems., David Arterburn, Leah Tuzzio, Jane Anau, Cara C Lewis, Neely Williams, Anita Courcoulas, Diana Stilwell, Ali Tavakkoli, Bestoun Ahmed, Margie Wilcox, Gary S Fischer, Kathleen Paul, Matt Handley, Anirban Gupta, and Kathleen McTigue

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Retinal mid-peripheral capillary free zones are enlarged in cognitively unimpaired older adults at high risk for Alzheimer's disease., Edmund Arthur, Swetha Ravichandran, Peter J Snyder, Jessica Alber, Jennifer Strenger, Ava K Bittner, Rima Khankan, Stephanie L Adams, Nicole M Putnam, Karin R Lypka, Juan A Piantino, and Stuart Sinoff

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Results of an American College of Radiology-Society of Interventional Radiology Membership Survey on Exclusive Contracts and the Attitudes of Interventional Radiologists., Ezana M Azene, Mary J Tarrant, Susan M Frankki, R Torrance Andrews, Mary Costantino, Gerald A Niedzwiecki, Laura K Findeiss, Alda L Tam, Timothy L Swan, Elizabeth A Ignacio, Robert S Pyatt, and Alan H Matsumoto

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Temporal Profiling of Host Proteome against Different, Prabhakar Babele, Mukul K Midha, Kanury V S Rao, and Ajay Kumar

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Impact of Pre-Advanced Pharmacy Practice Experience (APPE) Curriculum on Student Pharmacists' Professional Identity Formation., Jennifer L Bacci, Jasmine S Mangrum, Curtis G Jefferson, Tim Soverns, Gregory Gin, Kaylin Wakuzawa, Sydney Goo, and Peggy Odegard

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Rare presence of Charcot-Leyden crystals in acute myeloid leukemia., Sujan Badal, Mahnoosh Taheri, Peter Jiang, and Kirstine Oh

Kidney disease outcomes with semaglutide versus placebo across baseline KDIGO risk categories: a post-hoc analysis of SUSTAIN 6, SC Bain, Katherine Tuttle, and See Full List of Authors in Comments

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Integrated unbiased multiomics defines disease-independent placental clusters in common obstetrical syndromes., Oren Barak, Tyler Lovelace, Samantha Piekos, Tianjiao Chu, Zhishen Cao, Elena Sadovsky, Jean-Francois Mouillet, Yingshi Ouyang, W Tony Parks, Leroy Hood, Nathan D Price, Panayiotis V Benos, and Yoel Sadovsky

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Patient clusters identified by machine learning from a pooled analysis of the clinical development programme of secukinumab in psoriatic arthritis, ankylosing spondylitis and psoriatic arthritis with axial manifestations., Xenofon Baraliakos, Effie Pournara, Laura C Coates, Philip Mease, Samad S Jahandideh, and Dafna D Gladman

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An expanded safety/feasibility study of the EMulate Therapeutics Voyager™ System in patients with recurrent glioblastoma., Garni Barkhoudarian, Michael Badruddoja, Nicholas Blondin, Sajeel Chowdhary, Charles Cobbs, Julius Paul Duic, John Paul Flores, Ekokobe Fonkem, Edward McClay, Louis Burt Nabors, Michael Salacz, Lynn Taylor, Brian Vaillant, Jaya Gill, and Santosh Kesari

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Using a Comprehensive On-Site Assessment Process to Reduce Central Line-Associated Bloodstream Infection Rates, Rebecca Bartles, Andria Moore, Rosemary Martin, Rebecca Clarkson, and Laura Ebinger

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Health-care expenditures are less for minimally invasive than open colectomy for colon cancer: A US commercial claims database analysis., Amir L Bastawrous, I-Fan Shih, Yanli Li, Marissa Khalil, Biruk Almaz, and Robert K Cleary

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Interhospital variability in failure to rescue rates following aortic valve surgery., Tyler M Bauer, Michael Pienta, Xiaoting Wu, Eric J Lehr, Glenn J R Whitman, Robert S Kramer, James Brevig, Francis D Pagani, and Donald S Likosky

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Preventing CHF hospitalizations in patients with dementia, John Beale, Zoe Tartz, Jackson Harley, Tory Starzyk, Matthew Kennedy, and Colleen Zimmermann

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Kidney Biopsy Utility: Patient and Clinician Perspectives from the Kidney Precision Medicine Project., Lauren Bernard, Ashley R Wang, Steven Menez, Joel M Henderson, Ashveena Dighe, Glenda V Roberts, Christine Stutzke, Katherine Tuttle, R Tyler Miller, and Kidney Precision Medicine Project

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Resection Techniques During Robotic Partial Nephrectomy: A Systematic Review., Riccardo Bertolo, Alessio Pecoraro, Umberto Carbonara, Daniele Amparore, Pietro Diana, Stijn Muselaers, Michele Marchioni, Maria Carmen Mir, Alessandro Antonelli, Ketan Badani, Alberto Breda, Ben Challacombe, Jihad Kaouk, Alexandre Mottrie, Francesco Porpiglia, Jim Porter, Andrea Minervini, and Riccardo Campi

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Would you do it again? Discrepancies between patient and surgeon perceptions following adult spine deformity surgery., Shay Bess, Breton Line, Christopher Ames, Douglas Burton, Gregory Mundis, Robert Eastlack, Robert A Hart, Munish Gupta, Eric Klineberg, Han Jo Kim, Richard Hostin, Khaled Kebaish, Virgine Lafage, Renaud Lafage, Frank Schwab, Christopher Shaffrey, and Justin S Smith

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Postoperative Discharge to Acute Rehabilitation or Skilled Nursing Facility Compared to Home Does Not Reduce Hospital Readmissions, Return to Surgery or Improve Outcomes Following Adult Spine Deformity Surgery., Shay Bess, Breton G Line, Pierce Nunley, Christopher Ames, Douglas Burton, Gregory Mundis, Robert Eastlack, Robert A Hart, Munish Gupta, Eric Klineberg, Han Jo Kim, Michael Kelly, Richard Hostin, Khaled Kebaish, Virgine Lafage, Renaud Lafage, Frank Schwab, Christopher Shaffrey, Justin S Smith, and International Spine Study Group

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Difficult Conversations: Outcomes of Emergency Department Nurse-Directed Goals-of-Care Discussions., Suzanne Bigelow, Ron Medzon, Mari Siegel, and Ruyun Jin

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Doubling down on the future of gynecologic oncology: The SGO future of the profession summit report., Stephanie V Blank, Warner K Huh, Maria Bell, Sarah Dilley, Melissa Hardesty, Ebony R Hoskins, Jason Lachance, Fernanda Musa, Emily Prendergast, B J Rimel, Mark Shahin, and Fidel Valea

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Microbial community-scale metabolic modeling predicts personalized short-chain-fatty-acid production profiles in the human gut., Nick Bohmann, Tomasz Wilmanski, Lisa Levy, Johanna W Lampe, Thomas Gurry, Noa Rappaport, Christian Diener, and Sean M Gibbons

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Therapeutic trials for long COVID-19: A call to action from the interventions taskforce of the RECOVER initiative., Hector Bonilla, Michael J Peluso, Kathleen Rodgers, Judith A Aberg, Thomas F Patterson, Robert Tamburro, Lawrence Baizer, Jason D Goldman, Nadine Rouphael, Amelia Deitchman, Jeffrey Fine, Paul Fontelo, Arthur Y Kim, Gwendolyn Shaw, Jeran Stratford, Patricia Ceger, Maged M Costantine, Liza Fisher, Lisa O'Brien, Christine Maughan, John G Quigley, Vilma Gabbay, Sindhu Mohandas, David Williams, and Grace A McComsey

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spongEffects: ceRNA modules offer patient-specific insights into the miRNA regulatory landscape., Fabio Boniolo, Markus Hoffmann, Norman Roggendorf, Bahar Tercan, Jan Baumbach, Mauro A A Castro, A Gordon Robertson, Dieter Saur, and Markus List

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OPTN required SARS-CoV-2 lower respiratory testing for lung donors: Striking the balance., Sarah E Booker, Courtney Jett, Cole Fox, Judith A Anesi, Gerald J Berry, Kelly E Dunn, Cynthia E Fisher, Jason D Goldman, Chak-Sum Ho, Michelle Kittleson, Dong Heun Lee, Deborah J Levine, Charles C Marboe, Gary Marklin, Carlos Martinez, Raymund R Razonable, Marty T Sellers, Sarah Taimur, Helen S Te, Anil J Trindade, R Patrick Wood, Ann E Woolley, Lorenzo Zaffiri, David K Klassen, Marian G Michaels, Stephanie M Pouch, Lara Danziger-Isakov, and Ricardo M La Hoz

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ASO Visual Abstract: Changes in Surgical Management of the Axilla Over 11 Years-Report on Over 1500 Breast Cancer Patients Treated with Neoadjuvant Chemotherapy on the Prospective I-SPY2 Trial., Judy C Boughey, Hongmei Yu, Catherine Lu Dugan, Mara A Piltin, Lauren Postlewait, Jennifer D Son, Kirsten K Edmiston, Constantine Godellas, Marie C Lee, Michael J Carr, Jennifer E Tonneson, Angelena Crown, Rachel B Lancaster, Hannah E Woriax, Cheryl A Ewing, Harrison S Chau, Anne K Patterson, Jasmine M Wong, Michael D Alvarado, Rachel L Yang, Theresa W Chan, Jori B Sheade, Gretchen M Ahrendt, Kelsey E Larson, Kayla Switalla, Todd M Tuttle, Julia C Tchou, Roshni Rao, Nina Tamirisa, Puneet Singh, Rebekah E Gould, Alicia Terando, Candice Sauder, Kelly Hewitt, Akiko Chiba, Laura J Esserman, and Rita Mukhtar

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Changes in Surgical Management of the Axilla Over 11 Years - Report on More Than 1500 Breast Cancer Patients Treated with Neoadjuvant Chemotherapy on the Prospective I-SPY2 Trial., Judy C Boughey, Hongmei Yu, Catherine Lu Dugan, Mara A Piltin, Lauren Postlewait, Jennifer D Son, Kirsten K Edmiston, Constantine V Godellas, Marie C Lee, Michael J Carr, Jennifer E Tonneson, Angelena Crown, Rachel B Lancaster, Hannah E Woriax, Cheryl A Ewing, Harrison S Chau, Anne K Patterson, Jasmine M Wong, Michael D Alvarado, Rachel L Yang, Theresa W Chan, Jori B Sheade, Gretchen M Ahrendt, Kelsey E Larson, Kayla Switalla, Todd M Tuttle, Julia C Tchou, Roshni Rao, Nina Tamirisa, Puneet Singh, Rebekah E Gould, Alicia Terando, Candice Sauder, Kelly Hewitt, Akiko Chiba, Laura J Esserman, and Rita A Mukhtar

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Driving Toward a Culture of “Zero CAUTIs”, M Bowe, E Bowen, S Carlton, L Dyjur, P Harmon, J Harrod, and L Jackson

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Orientation materials: Impact of Transitioning from Paper to an Electronic Format, Megan Bowles, Abby Lust, Teresa Rangel, and Tobi Bryan

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Single-haplotype comparative genomics provides insights into lineage-specific structural variation during cat evolution., Kevin R Bredemeyer, LaDeana Hillier, Andrew J Harris, Graham M Hughes, Nicole M Foley, Colleen Lawless, Rachel A Carroll, Jessica Storer, Mark A Batzer, Edward S Rice, Brian W Davis, Terje Raudsepp, Stephen J O'Brien, Leslie A Lyons, Wesley C Warren, and William J Murphy

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Oral examination of fourth-year medical students on surgery rotations allows faculty to assess Core Entrustable Professional Activities for entering Residency (CEPAR): Proof-of-concept and analysis of student submissions., Tamir Bresler, Erik Stiles, Shaina Schaeztel, Christopher Freeman, Ben Chia, and Anjali Kumar

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Non-Invasive Transcutaneous Afferent Patterned Stimulation Therapy Offers Action Tremor Relief in Parkinson's Disease., Salima Brillman, Pravin Khemani, Stuart H Isaacson, Rajesh Pahwa, Ruta Deshpande, Vivien Zraick, Apoorva Rajagopal, Dhira Khosla, and Kathryn H Rosenbluth

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Intravenous aviptadil and remdesivir for treatment of COVID-19-associated hypoxaemic respiratory failure in the USA (TESICO): a randomised, placebo-controlled trial., Samuel M Brown, Christina E Barkauskas, Birgit Grund, Shweta Sharma, Andrew N Phillips, Lindsay Leither, Ithan D Peltan, Michael Lanspa, Daniel L Gilstrap, Ahmad Mourad, Kathleen Lane, Jeremy R Beitler, Alexis L Serra, Ivan Garcia, Eyad Almasri, Mohamed Fayed, Kinsley Hubel, Estelle S Harris, Elizabeth A Middleton, Macy A G Barrios, Kusum S Mathews, Neha N Goel, Samuel Acquah, Jarrod Mosier, Cameron Hypes, Elizabeth Salvagio Campbell, Akram Khan, Catherine L Hough, Jennifer G Wilson, Joseph E Levitt, Abhijit Duggal, Siddharth Dugar, Andrew J Goodwin, Charles Terry, Peter Chen, Sam Torbati, Nithya Iyer, Uriel S Sandkovsky, Nicholas J Johnson, Bryce R H Robinson, Michael A Matthay, Neil R Aggarwal, Ivor S Douglas, Jonathan D Casey, Manuel Hache-Marliere, J Georges Youssef, William Nkemdirim, Brad Leshnower, Omar Awan, Sonal Pannu, Darragh Shane O'Mahony, Prasad Manian, J W Awori Hayanga, Glenn W Wortmann, Bruno M Tomazini, Robert F Miller, Jens-Ulrik Jensen, Daniel D Murray, Nina A Bickell, Jigna Zatakia, Sarah Burris, Elizabeth S Higgs, Ven Natarajan, Robin L Dewar, Adam Schechner, Nayon Kang, Alejandro Arenas-Pinto, Fleur Hudson, Adit A Ginde, Wesley H Self, Angela J Rogers, Cathryn F Oldmixon, Haley Morin, Adriana Sanchez, Amy C Weintrob, Alexandre Biasi Cavalcanti, Anne Davis-Karim, Nicole Engen, Eileen Denning, B Taylor Thompson, Annetine C Gelijns, Virginia Kan, Victoria J Davey, Jens D Lundgren, Abdel G Babiker, James D Neaton, H Clifford Lane, and ACTIV-3b/Therapeutics for Severely Ill Inpatients with COVID-19 (TESICO) Study Group

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Safety profile of upadacitinib over 15 000 patient-years across rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and atopic dermatitis., Gerd R Burmester, Stanley B Cohen, Kevin L Winthrop, Peter Nash, Alan D Irvine, Atul Deodhar, Eduardo Mysler, Yoshiya Tanaka, John Liu, Ana P Lacerda, Hannah Palac, Tim Shaw, Philip J Mease, and Emma Guttman-Yassky

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Identifying Systemic errors in refilling insulin to prevent another hospitalization: An RCA, John Butler, Mikayla Button, Jared Fincher, Rakin Solaiman, and Michael Woodfin

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American Society for Gastrointestinal Endoscopy guideline on post-ERCP pancreatitis prevention strategies: methodology and review of evidence., James L Buxbaum, Martin Freeman, Stuart K Amateau, Jean M Chalhoub, Aneesa Chowdhury, Nayantara Coelho-Prabhu, Rishi Das, Madhav Desai, Sherif E Elhanafi, Nauzer Forbes, Larissa L Fujii-Lau, Divyanshoo R Kohli, Richard S Kwon, Jorge D Machicado, Neil B Marya, Swati Pawa, Wenly H Ruan, Jonathan Sadik, Sunil G Sheth, Nikhil R Thiruvengadam, Nirav C Thosani, Selena Zhou, and Bashar J Qumseya

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American Society for Gastrointestinal Endoscopy guideline on post-ERCP pancreatitis prevention strategies: summary and recommendations., James L Buxbaum, Martin Freeman, Stuart K Amateau, Jean M Chalhoub, Nayantara Coelho-Prabhu, Madhav Desai, Sherif E Elhanafi, Nauzer Forbes, Larissa L Fujii-Lau, Divyanshoo R Kohli, Richard S Kwon, Jorge D Machicado, Neil B Marya, Swati Pawa, Wenly H Ruan, Sunil G Sheth, Nikhil R Thiruvengadam, Nirav C Thosani, and Bashar J Qumseya

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Incorporating radioligand therapy in clinical practice in the United States for patients with prostate cancer., Jeremie Calais, Stephen M Eulau, Linda Gardner, Ralph J Hauke, Ayse T Kendi, Neal D Shore, and Song Zhao