Providence research from Washington locations.

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Submissions from 2023

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Upadacitinib in patients with psoriatic arthritis and inadequate response to biologics: 3-year results from the open-label extension of the randomised controlled phase 3 SELECT-PsA 2 study., Philip Mease, Arathi Setty, Kim Papp, Filip Van den Bosch, Shigeyoshi Tsuji, Mauro Keiserman, Kyle Carter, Yihan Li, Reva McCaskill, Erin McDearmon-Blondell, Peter Wung, and William Tillett

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Best Practices in Esophageal, Gastroduodenal, and Colonic Stenting., Renato Medas, Joel Ferreira-Silva, Mohit Girotra, Monique Barakat, James H Tabibian, and Eduardo Rodrigues-Pinto

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Utilization of TandemHeart in cardiogenic shock: Insights from the THEME registry., Michael Megaly, Chaun Gandolfo, Samer Zakhour, Mei Jiang, Kristie Burgess, Stanley Chetcuti, Michael Ragosta, Eric Adler, Andrew Coletti, Brian O'Neill, Khaldoon Alaswad, and Mir B Basir

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Muscle mass cross-sectional area is associated with survival outcomes in malignant pleural disease related to lung cancer., Austin M Meggyesy, Candice L Wilshire, Shu-Ching Chang, Jed A Gorden, and Christopher R Gilbert

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Baseline modern medical management in the BEST-CLI trial., Matthew T Menard, Michael R Jaff, Alik Farber, Kenneth Rosenfield, Michael S Conte, Christopher J White, Joshua A Beckman, Niteesh K Choudhry, Leonardo C Clavijo, Thomas S Huber, Katherine R Tuttle, Taye H Hamza, Andres Schanzer, Igor A Laskowski, Mark J Cziraky, Alain Drooz, Max van Over, Michael B Strong, and Ido Weinberg

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Cobimetinib Plus Vemurafenib in Patients With Solid Tumors With, Funda Meric-Bernstam, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Rodolfo Gutierrez, Eugene R Ahn, Timothy L Cannon, Steven Powell, John C Krauss, Christopher M Reynolds, Margaret von Mehren, Deepti Behl, Carmen J Calfa, Herbert L Duvivier, Henry G Kaplan, Michael B Livingston, Manish R Sharma, Walter Urba, Gina N Grantham, Dominique C Hinshaw, Abigail Gregory, Susan Halabi, and Richard L Schilsky

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Bimekizumab in patients with active psoriatic arthritis and previous inadequate response or intolerance to tumour necrosis factor-α inhibitors: a randomised, double-blind, placebo-controlled, phase 3 trial (BE COMPLETE)., Joseph F Merola, Robert Landewé, Iain B McInnes, Philip Mease, Christopher T Ritchlin, Yoshiya Tanaka, Akihiko Asahina, Frank Behrens, Dafna D Gladman, Laure Gossec, Alice B Gottlieb, Diamant Thaçi, Richard B Warren, Barbara Ink, Deepak Assudani, Rajan Bajracharya, Vishvesh Shende, Jason Coarse, and Laura C Coates

Comparison of in-clinic only to in-clinic plus virtual mental health screens of adults with cystic fibrosis during SARS-CoV-2 pandemic, KG Mertz, M Ingoldby, T Vance, and AA Lambert

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Physical Therapist Management of Glenohumeral Joint Osteoarthritis: A Clinical Practice Guideline from the American Physical Therapy Association., Lori A Michener, Jill Heitzman, Laurel D Abbruzzese, Salvador L Bondoc, Kristin Bowne, Phillip Troy Henning, Heidi Kosakowski, Brian G Leggin, Ann M Lucado, and Amee L Seitz

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Glucagon-like peptide-1 receptor agonists in diabetic kidney disease: A review of their kidney and heart protection., Erin D Michos, George L Bakris, Helena W Rodbard, and Katherine Tuttle

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Glucagon-like peptide-1 receptor agonists in diabetic kidney disease: A review of their kidney and heart protection., Erin D Michos, George L Bakris, Helena W Rodbard, and Katherine R Tuttle

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Vacuum Insulated Probe Heated Electrospray Ionization Source Enhances Microflow Rate Chromatography Signals in the Bruker timsTOF Mass Spectrometer., Mukul K Midha, Charu Kapil, Michal Maes, David H Baxter, Seamus R Morrone, Timothy J Prokop, and Robert L Moritz

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Novel TCF4:TCF12 heterodimer inhibits glioblastoma growth., Svetlana A Mikheeva, Cory C Funk, Philip J Horner, Robert C Rostomily, and Andrei M Mikheev

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Enhancing Respiratory Therapists' Well-Being: Battling Burnout in Respiratory Care., Andrew G Miller, Katlyn L Burr, Jerin Juby, Carl R Hinkson, Cheryl A Hoerr, Karsten J Roberts, Brian J Smith, Shawna L Strickland, and Kyle J Rehder

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Characteristics, Identification, Training, and Perception of Leaders in Respiratory Care., Andrew G Miller, Jerin Juby, Katlyn L Burr, Karsten J Roberts, Carl R Hinkson, Cheryl Hoerr, Brian J Smith, and Kyle J Rehder

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A Guide to Expanding the Use of Buprenorphine Beyond Standard Initiations for Opioid Use Disorder., James Miller, Michael A Brooks, Kelly Wurzel, Emily J Cox, and John F Wurzel

Improvement: Increasing staff and patient awareness of and knowledge of genetic therapy research, JE Milton, A Chavez, K Kuykendall, and AA Lambert

Quality Improvement: Increasing staff and patient awareness of and knowledge of genetic therapy research, Joan Milton

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Optimizing preclinical models of ageing for translation to clinical trials., Sarah J Mitchell, Michael R MacArthur, and Alice E Kane

“Cardiac Amyloid Pearls & Pitfalls”, Deirdre Mooney

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Rationale and Design of the Multicenter Catheter Ablation of Ventricular Tachycardia Before Transcatheter Pulmonary Valve Replacement in Repaired Tetralogy of Fallot Study., Jeremy P Moore, Jamil A Aboulhosn, Katja Zeppenfeld, Victor Waldmann, Francis Bessière, Nico A Blom, Nicolas Combes, Frank A Fish, Christopher J McLeod, Ronald J Kanter, Weiyi Tan, Nimesh Patel, Johannes C von Alvensleben, Anna Kamp, Michael S Lloyd, Chris Anderson, Reina B Tan, Elisabetta Mariucci, Daniel S Levi, Morris Salem, Kalyanam Shivkumar, and Paul Khairy

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Stereotactic and Functional Neurosurgery Convection-Enhanced Delivery of Autologous Cerebrospinal Fluid Enhances Basal Ganglia Visualization during MRI-Guided Deep Brain Stimulation Surgery., Shayan Moosa, Aaron E Bond, Tony R Wang, Faraz Farzad, Ashok R Asthagiri, and W Jeffrey Elias

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Identification of acute pathological heart rate variability variance using wearable technology and novel predictive software: A multi-disciplinary collaboration between St Luke’s Rehabilitation and Eastern Washington University, Trevor Mordhorst, Sanmeet Kaur, Dan Tappan, Dillon Dalton, Otto Bucholz, Katrina Taylor, Garth Babcock, Alicia Hegie, and Frank Jackson

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Benefits and challenges in implementation of artificial intelligence in colonoscopy: World Endoscopy Organization position statement., Yuichi Mori, James E East, Cesare Hassan, Natalie Halvorsen, Tyler M Berzin, Michael Byrne, Daniel von Renteln, David G Hewett, Alessandro Repici, Mohan Ramchandani, Maryam Al Khatry, Shin-Ei Kudo, Pu Wang, Honggang Yu, Yutaka Saito, Masashi Misawa, Sravanthi Parasa, Carolina Ogawa Matsubayashi, Haruhiko Ogata, Hisao Tajiri, Nonthalee Pausawasdi, Evelien Dekker, Omer F Ahmad, Prateek Sharma, and Douglas K Rex

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The scalable precision medicine open knowledge engine (SPOKE): a massive knowledge graph of biomedical information., John H Morris, Karthik Soman, Rabia E Akbas, Xiaoyuan Zhou, Brett Smith, Elaine C Meng, Conrad C Huang, Gabriel Cerono, Gundolf Schenk, Angela Rizk-Jackson, Adil Harroud, Lauren Sanders, Sylvain V Costes, Krish Bharat, Arjun Chakraborty, Alexander R Pico, Taline Mardirossian, Michael Keiser, Alice Tang, Josef Hardi, Yongmei Shi, Mark Musen, Sharat Israni, Sui Huang, Peter W Rose, Charlotte A Nelson, and Sergio E Baranzini

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Optimization of Instrument Parameters for Efficient Phosphopeptide Identification and Localization by Data-dependent Analysis Using Orbitrap Tribrid Mass Spectrometers, Seamus R. Morrone, Michael R Hoopmann, David Shteynberg, Ulrike Kusebauch, and Robert L Moritz

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Integrated analysis of proteomics, epigenomics and metabolomics data revealed divergent pathway activation patterns in the recent versus chronic post-traumatic stress disorder., Seid Muhie, Aarti Gautam, Burook Misganaw, Ruoting Yang, Synthia H Mellon, Allison Hoke, Janine Flory, Bernie Daigle, Kevin Swift, PTSD Systems Biology Consortium, Leroy Hood, Francis J Doyle, Owen M Wolkowitz, Charles R Marmar, Kerry Ressler, Rachel Yehuda, Rasha Hammamieh, and Marti Jett

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Molecular signatures of post-traumatic stress disorder in war-zone-exposed veteran and active-duty soldiers., Seid Muhie, Aarti Gautam, Ruoting Yang, Burook Misganaw, Bernie J Daigle, Synthia H Mellon, Janine D Flory, Duna Abu-Amara, Inyoul Lee, Kai Wang, Ryan Rampersaud, PTSD Systems Biology Consortium, Leroy Hood, Rachel Yehuda, Charles R Marmar, Owen M Wolkowitz, Kerry J Ressler, Francis J Doyle, Rasha Hammamieh, and Marti Jett

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Breast Conservation Surgery and Mastectomy have Similar Locoregional Recurrence Following Neoadjuvant Chemotherapy: Results from 1,462 Patients on the Prospective, Randomized I-SPY2 Trial., Rita A Mukhtar, Harrison Chau, Hannah Woriax, Mara Piltin, Gretchen Ahrendt, Julia Tchou, Hongmei Yu, Qian Ding, Catherine Lu Dugan, Jori Sheade, Angelena Crown, Michael Carr, Jasmine Wong, Jennifer Son, Rachel Yang, Theresa Chan, Alicia Terando, Michael Alvarado, Cheryl Ewing, Jennifer Tonneson, Nina Tamirisa, Rebekah Gould, Puneet Singh, Constantine Godellas, Kelsey Larson, Akiko Chiba, Roshni Rao, Candice Sauder, Lauren Postlewait, Marie Catherine Lee, William Fraser Symmans, Laura J Esserman, Judy C Boughey, and ISPY-2 Locoregional Working Group

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Preliminary experience with a novel facet-based lateral mass drill guide for the placement of lateral mass screws compared to freehand technique: a cadaveric study., Gregory M Mundis, Eric C Olsson, Robert A Hart, Seth K Williams, Ryan Martyn, Douglas G Orndorff, Anastasia L Berg, Nicholas A Russell, and Frank Vizesi

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Geographical region and clinical outcomes of patients with primary biliary cholangitis from Western Europe., Carla F Murillo Perez, Alessio Gerussi, Palak J Trivedi, Christophe Corpechot, Adriaan J van der Meer, Pier Maria Battezzati, Keith D Lindor, Frederik Nevens, Kris V Kowdley, Tony Bruns, Nora Cazzagon, Annarosa Floreani, Atsushi Tanaka, Xiong Ma, Andrew L Mason, Aliya Gulamhusein, Cyriel Y Ponsioen, Marco Carbone, Ana Lleo, Marlyn J Mayo, George N Dalekos, Nikolaos K Gatselis, Douglas Thorburn, Xavier Verhelst, Albert Parés, Harry L A Janssen, Gideon M Hirschfield, Bettina E Hansen, Pietro Invernizzi, Willem J Lammers, and GLOBAL PBC Study Group

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Signaling landscape of mitochondrial non-coding RNAs., Gnanavel Mutharasu, Akshaya Murugesan, Saravnan Kondamani, Ramesh Thiyagarajan, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Stereochemical engineering yields a multifunctional peptide macrocycle inhibitor of Akt2 by fine-tuning macrocycle-cell membrane interactions., Arundhati Nag, Amirhossein Mafi, Samir Das, Mary Beth Yu, Belen Alvarez-Villalonga, Soo-Kyung Kim, Yapeng Su, William A Goddard, and James R Heath

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The Impacts of Engagement in the Latino Medical Student Association., Sunny Nakae, Stacey Martinez, Jordan J Juarez, and Cintya Beltran Sanchez

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Factors Influencing Instrumental Birth Rates: An Evidence Based Project, Douglas Nanu, Gabriel Alemayehu, Chase Eby, and Teresa Rangel

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Mirizzi Syndrome in the Setting of Hemorrhagic Cholecystitis., Priscilla Natcher and Danielle Hayes

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Diabetes Management in Chronic Kidney Disease: Synopsis of the KDIGO 2022 Clinical Practice Guideline Update., Sankar D Navaneethan, Sophia Zoungas, M Luiza Caramori, Juliana C N Chan, Hiddo J L Heerspink, Clint Hurst, Adrian Liew, Erin D Michos, Wasiu A Olowu, Tami Sadusky, Nikhil Tandon, Katherine R Tuttle, Christoph Wanner, Katy G Wilkens, Jonathan C Craig, David J Tunnicliffe, Marcello Tonelli, Michael Cheung, Amy Earley, Peter Rossing, Ian H de Boer, and Kamlesh Khunti

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Toward an Integrated Machine Learning Model of a Proteomics Experiment., Benjamin A Neely, Viktoria Dorfer, Lennart Martens, Isabell Bludau, Robbin Bouwmeester, Sven Degroeve, Eric W Deutsch, Siegfried Gessulat, Lukas Käll, Pawel Palczynski, Samuel H Payne, Tobias Greisager Rehfeldt, Tobias Schmidt, Veit Schwämmle, Julian Uszkoreit, Juan Antonio Vizcaíno, Mathias Wilhelm, and Magnus Palmblad

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Effects of hemodilution on coagulation function during prolonged hypotensive resuscitation in a porcine model of severe hemorrhagic shock., Leslie E Neidert, Clifford G Morgan, Emily N Hathaway, Peter J Hemond, Michael M Tiller, Sylvain Cardin, and Jacob J Glaser

First-line therapy in T2D: Has Metformin been “dethroned, Josh Neumiller and Radica Alicic

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Incorporating Evidence and Guidelines for Personalized Care of Diabetes and Chronic Kidney Disease., Joshua J Neumiller, Radica Alicic, and Katherine Tuttle

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Organ-specific immunity: A tissue analysis framework for investigating local immune responses to SARS-CoV-2., Alphonsus H C Ng, Huiqian Hu, Kai Wang, Kelsey Scherler, Sarah E Warren, Daniel R Zollinger, Jill McKay-Fleisch, Kristina Sorg, Joseph M Beechem, Emily Ragaglia, J Matthew Lacy, Kelly D Smith, Desiree A Marshall, Michael M Bundesmann, Diego López de Castilla, David Corwin, Nicole Yarid, Beatrice S Knudsen, Yue Lu, Jason D Goldman, and James R Heath

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Proceedings of the GRAPPA 2022 Executive Retreat., Beverly Cheok Kuan Ng, Deepak Jadon, Adewale Adebajo, Gizem Ayan, Kristina Callis Duffin, Vinod Chandran, Laura C Coates, Maria Antonietta D'Agostino, Kurt de Vlam, Atul Deodhar, Lihi Eder, Amit Garg, Dafna D Gladman, Niti Goel, Alice B Gottlieb, M Elaine Husni, Arnon Katz, Arthur Kavanaugh, Ennio Lubrano, Philip Mease, Joseph F Merola, Peter Nash, Alexis Ogdie, Stephen R Pennington, Lourdes M Perez-Chada, Fabian Proft, Cheryl F Rosen, Laura Savage, Claudia Goldenstein-Schainberg, Stefan Siebert, Enrique R Soriano, Ingrid Steinkoenig, William Tillett, April W Armstrong, and Oliver FitzGerald

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Proceedings of the Collaborative Research Network Meeting at the GRAPPA 2022 Annual Meeting., Beverly Cheok Kuan Ng, Deepak Jadon, Frank Behrens, Maarten de Wit, Oliver FitzGerald, Dafna D Gladman, Philip Mease, Denis O'Sullivan, Stephen R Pennington, Georg Schett, Vinod Chandran, and Kurt de Vlam

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Integrated Hospital- and Home-Based Palliative Care for Cancer Patients in Vietnam: People-Centered Outcomes., Viet Nguyen, Quach Thanh Khanh, Mevhibe Hocaoglu, Hoang Thi Mong Huyen, Dang Huy Quoc Thinh, and Eric L Krakauer

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Disparities in the Use of SGLT2 Inhibitors and Glucagon-like Peptide-1 Receptor Agonists in Adults With CKD in the United States., Susanne B Nicholas, Radica Alicic, and Jenny Shen

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Disparities in the Use of SGLT2 Inhibitors and Glucagon-like Peptide-1 Receptor Agonists in Adults With CKD in the United States., Susanne B Nicholas, Radica Z Alicic, and Jenny Shen

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Prescription of guideline-directed medical therapies in patients with diabetes and chronic kidney disease from the CURE-CKD Registry, 2019-2020., Susanne B Nicholas, Kenn Daratha, Radica Alicic, Cami R Jones, Lindsey M Kornowske, Joshua J Neumiller, Samuel T Fatoba, Sheldon X Kong, Rakesh Singh, Keith C Norris, and Katherine Tuttle

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Computational capabilities of a multicellular reservoir computing system., Vladimir Nikolić, Moriah Echlin, Boris Aguilar, and Ilya Shmulevich

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A Plain Language Summary of Results from the GARNET Study of Dostarlimab in Patients with Endometrial Cancer., Ana Oaknin, Lucy Gilbert, Anna V Tinker, Jubilee Brown, Cara Mathews, Joshua Press, Renaud Sabatier, David M O'Malley, Vanessa Samouelian, Valentina Boni, Linda Duska, Sharad Ghamande, Prafull Ghatage, Rebecca Kristeleit, Charles Leath, Yuping Dong, Jennifer Veneris, and Bhavana Pothuri

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Inhibition of Interleukin-17 in Patients with Oligoarticular Psoriatic Arthritis., Alexis Ogdie, Dafna D Gladman, Laura C Coates, Effie Pournara, Bhumik Parikh, and Philip Mease

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Abatacept, Cenicriviroc, or Infliximab for Treatment of Adults Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial., Jane A O'Halloran, Emily R Ko, Kevin J Anstrom, Eyal Kedar, Matthew W McCarthy, Reynold A Panettieri, Martin Maillo, Patricia Segura Nunez, Anne M Lachiewicz, Cynthia Gonzalez, P Brian Smith, Sabina Mendivil-Tuchia de Tai, Akram Khan, Alfredo J Mena Lora, Matthias Salathe, Gerardo Capo, Daniel Rodríguez Gonzalez, Thomas F Patterson, Christopher Palma, Horacio Ariza, Maria Patelli Lima, John Blamoun, Esteban C Nannini, Eduardo Sprinz, Analia Mykietiuk, Radica Alicic, Adriana M Rauseo, Cameron R Wolfe, Britta Witting, Jennifer P Wang, Luis Parra-Rodriguez, Tatyana Der, Kate Willsey, Jun Wen, Adam Silverstein, Sean M O'Brien, Hussein R Al-Khalidi, Michael A Maldonado, Richard Melsheimer, William G Ferguson, Steven E McNulty, Pearl Zakroysky, Susan Halabi, Daniel K Benjamin, Sandra Butler, Jane C Atkinson, Stacey J Adam, Soju Chang, Lisa LaVange, Michael Proschan, Samuel A Bozzette, William G Powderly, and ACTIV-1 IM Study Group Members

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Operative and oncological outcomes of salvage robotic radical and partial nephrectomy: a multicenter experience., Kennedy E Okhawere, Ralph Grauer, Laura Zuluaga, Kirolos N Meilika, Burak Ucpinar, Alp Tuna Beksac, Shirin Razdan, Indu Saini, Chiya Abramowitz, Ronney Abaza, Daniel D Eun, Akshay Bhandari, Ashok K Hemal, James Porter, Michael D Stifelman, Mani Menon, and Ketan K Badani

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Transperitoneal Versus Retroperitoneal Robotic-Assisted Partial Nephrectomy in Patients with Obesity., Kennedy E Okhawere, Jordan Miller Rich, Alp Tuna Beksac, Laura Zuluaga, Indu Saini, Burak Ucpinar, Joshua Levieddin, Iretiayo T Joel, Anthony Deluxe, Michael D Stifelman, Simone Crivellaro, Ronney Abaza, Daniel D Eun, Akshay Bhandari, Ashok K Hemal, James Porter, Ahmed Mansour, Phillip M Pierorazio, Osama Zaytoun, and Ketan K Badani

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TN-RS: a novel scoring system predicts Gamma Knife Radiosurgery outcome for trigeminal neuralgia patients., Alon Orlev, James Feghali, Gil Kimchi, Lian Sun, Clifford A Pierre, Cristian Gragnaniello, Cristian Cotrutz, Christopher Loiselle, Sandra Vermeulen, and Zachary Litvack

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Insights into mammalian TE diversity through the curation of 248 genome assemblies., Austin B Osmanski, Nicole S Paulat, Jenny Korstian, Jenna R Grimshaw, Michaela Halsey, Kevin A M Sullivan, Diana D Moreno-Santillán, Claudia Crookshanks, Jacquelyn Roberts, Carlos Garcia, Matthew G Johnson, Llewellyn D Densmore, Richard D Stevens, Jeb Rosen, Jessica Storer, Robert Hubley, Arian F A Smit, Liliana M Dávalos, Elinor K Karlsson, Kerstin Lindblad-Toh, and David A Ray

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Framework and metrics for the clinical use and implementation of artificial intelligence algorithms into endoscopy practice: recommendations from the American Society for Gastrointestinal Endoscopy Artificial Intelligence Task Force., Sravanthi Parasa, Alessandro Repici, Tyler Berzin, Cadman Leggett, Seth A Gross, and Prateek Sharma

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Preventable Tacrolimus Toxicity, Brooke Parker, Jessica Sterner, John Mele, Laura DeWald, and Cassidy Johnston

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The impact of baseline cervical malalignment on the development of proximal junctional kyphosis following surgical correction of thoracolumbar adult spinal deformity., Lara Passfall, Bailey Imbo, Virginie Lafage, Renaud Lafage, Justin S Smith, Breton Line, Andrew J Schoenfeld, Themistocles Protopsaltis, Alan H Daniels, Khaled M Kebaish, Jeffrey L Gum, Heiko Koller, D Kojo Hamilton, Richard Hostin, Munish Gupta, Neel Anand, Christopher P Ames, Robert Hart, Douglas Burton, Frank J Schwab, Christopher I Shaffrey, Eric O Klineberg, Han Jo Kim, Shay Bess, and Peter G Passias

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Economic burden of nonoperative treatment of adult spinal deformity., Peter G Passias, Waleed Ahmad, Pooja Dave, Renaud Lafage, Virginie Lafage, Jamshaid Mir, Eric O Klineberg, Khaled M Kabeish, Jeffrey L Gum, Breton G Line, Robert A Hart, Douglas Burton, Justin S Smith, Christopher P Ames, Christopher I Shaffrey, Frank Schwab, Richard Hostin, Thomas Buell, D Kojo Hamilton, and Shay Bess

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Identifying Subsets of Patients With Adult Spinal Deformity Who Maintained a Positive Response to Nonoperative Management., Peter G Passias, Waleed Ahmad, Peter Tretiakov, Oscar Krol, Frank Segreto, Renaud Lafage, Virginie Lafage, Alex Soroceanu, Alan Daniels, Jeffrey Gum, Breton Line, Andrew J Schoenfeld, Shaleen Vira, Robert Hart, Douglas Burton, Justin S Smith, Christopher P Ames, Christopher Shaffrey, Frank Schwab, Shay Bess, and International Spine Study Group

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Critical Analysis of Radiographic and Patient Reported Outcomes Following Anterior/Posterior Staged vs. Same Day Surgery in Patients Undergoing Identical Corrective Surgery for Adult Spinal Deformity., Peter G Passias, Waleed Ahmad, Peter S Tretiakov, Renaud Lafage, Virginie Lafage, Andrew J Schoenfeld, Breton Line, Alan Daniels, Jamshaid M Mir, Munish Gupta, Gregory Mundis, Robert Eastlack, Pierce Nunley, D Kojo Hamilton, Richard Hostin, Robert Hart, Douglas C Burton, Christopher Shaffrey, Frank Schwab, Christopher Ames, Justin S Smith, Shay Bess, Eric O Klineberg, and International Spine Study Group

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Efficacy of Varying Surgical Approaches on Achieving Optimal Alignment in Adult Spinal Deformity Surgery., Peter G Passias, Waleed Ahmad, Tyler K Williamson, Jordan Lebovic, Khaled Kebaish, Renaud Lafage, Virginie Lafage, Breton Line, Andrew J Schoenfeld, Bassel G Diebo, Eric O Klineberg, Han Jo Kim, Christopher P Ames, Alan H Daniels, Justin S Smith, Christopher I Shaffrey, Douglas C Burton, Robert A Hart, Shay Bess, Frank J Schwab, Munish C Gupta, and International Spine Study Group

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Patient-specific Cervical Deformity Corrections With Consideration of Associated Risk: Establishment of Risk Benefit Thresholds for Invasiveness Based on Deformity and Frailty Severity., Peter G Passias, Katherine E Pierce, Tyler K Williamson, Jordan Lebovic, Andrew J Schoenfeld, Renaud Lafage, Virginie Lafage, Jeffrey L Gum, Robert Eastlack, Han Jo Kim, Eric O Klineberg, Alan H Daniels, Themistocles S Protopsaltis, Gregory M Mundis, Justin K Scheer, Paul Park, Dean Chou, Breton Line, Robert A Hart, Douglas C Burton, Shay Bess, Frank J Schwab, Christopher I Shaffrey, Justin S Smith, and Christopher P Ames

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Incremental benefits of circumferential minimally invasive surgery for increasingly frail patients with adult spinal deformity., Peter G Passias, Peter S Tretiakov, Pierce D Nunley, Michael Y Wang, Paul Park, Adam S Kanter, David O Okonkwo, Robert K Eastlack, Gregory M Mundis, Dean Chou, Nitin Agarwal, Richard G Fessler, Juan S Uribe, Neel Anand, Khoi D Than, Gregory Brusko, Kai-Ming Fu, Jay D Turner, Vivian P Le, Breton G Line, Christopher P Ames, Justin S Smith, Christopher I Shaffrey, Robert A Hart, Douglas Burton, Renaud Lafage, Virginie Lafage, Frank Schwab, Shay Bess, and Praveen V Mummaneni

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Cost Benefit of Implementation of Risk Stratification Models for Adult Spinal Deformity Surgery., Peter G Passias, Tyler K Williamson, Nicholas A Kummer, Ferran Pellisé, Virginie Lafage, Renaud Lafage, Miguel Serra-Burriel, Justin S Smith, Breton Line, Shaleen Vira, Jeffrey L Gum, Sleiman Haddad, Francisco Javier Sánchez Pérez-Grueso, Andrew J Schoenfeld, Alan H Daniels, Dean Chou, Eric O Klineberg, Munish C Gupta, Khaled M Kebaish, Michael P Kelly, Robert A Hart, Douglas C Burton, Frank Kleinstück, Ibrahim Obeid, Christopher I Shaffrey, Ahmet Alanay, Christopher P Ames, Frank J Schwab, Richard A Hostin, Shay Bess, and International Spine Study Group

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Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery., Peter G Passias, Tyler K Williamson, Jamshaid M Mir, Justin S Smith, Virginie Lafage, Renaud Lafage, Breton Line, Alan H Daniels, Jeffrey L Gum, Andrew J Schoenfeld, David Kojo Hamilton, Alex Soroceanu, Justin K Scheer, Robert Eastlack, Gregory M Mundis, Bassel Diebo, Khaled M Kebaish, Richard A Hostin, Munish C Gupta, Han Jo Kim, Eric O Klineberg, Christopher P Ames, Robert A Hart, Douglas C Burton, Frank J Schwab, Christopher I Shaffrey, Shay Bess, and On Behalf Of The International Spine Study Group

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268 - Outpatient CAR T Cell Therapy Is Safe and Feasible in Patients with Lymphoma Treated in Non-University Medical Centers: A Multicenter, Retrospective Analysis, Krish Patel, Megumi Bailey, Neil Bailey, Suzanne Fanning, Kayla Gulley, Jens Frisvold, Sonia Glennie, Vanessa Dunleavy, Sandra Benitez-Kruidenier, Julia Parker, Shannon Williams, Suzan Sullivan, Carol Dean, Heidi Hohmann, Chiachun Lu, Catherine Tierney, Grace Mun, Daniel N Egan, and James Essell

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Elevation of cannabis knowledge: higher learning, Savannah Marie Patterson and Anisha Boetel

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Chiropterans Are a Hotspot for Horizontal Transfer of DNA Transposons in Mammalia., Nicole S Paulat, Jessica Storer, Diana D Moreno-Santillán, Austin B Osmanski, Kevin A M Sullivan, Jenna R Grimshaw, Jennifer Korstian, Michaela Halsey, Carlos J Garcia, Claudia Crookshanks, Jaquelyn Roberts, Arian F A Smit, Robert Hubley, Jeb Rosen, Emma C Teeling, Sonja C Vernes, Eugene Myers, Martin Pippel, Thomas Brown, Michael Hiller, Danny Rojas, Liliana M Dávalos, Kerstin Lindblad-Toh, Elinor K Karlsson, and David A Ray

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Incidence, demographics, and survival of malignant hemangioendothelioma in the United States., Kelly G Paulson, Vinod Ravi, Brian P Rubin, Min Park, Elizabeth T Loggers, Lee D Cranmer, and Michael J Wagner

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Acute Infectious Proctitis Caused by Anorectal Sexually Transmitted Infections., Jordan A Paulus-Andres and Marta M Lavery

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ASGE Guideline on the Role of Ergonomics for Prevention of Endoscopy-related Injury (ERI): Summary and Recommendations., Swati Pawa, Richard S Kwon, Douglas S Fishman, Nirav C Thosani, Amandeep Shergill, Samir Grover, Mohammad Al-Haddad, Stuart K Amateau, James L Buxbaum, Audrey H Calderwood, Jean M Chalhoub, Nayantara Coelho-Prabhu, Madhav Desai, Sherif E Elhanafi, Nauzer Forbes, Larissa L Fujii-Lau, Divyanshoo R Kohli, Jorge D Machicado, Neil B Marya, Wenly Ruan, Sunil G Sheth, Andrew Storm, Nikhil R Thiruvengadam, and Bashar J Qumseya

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ASGE Guideline on the Role of Ergonomics for Prevention of Endoscopy-related Injury (ERI): Methodology and Review of Evidence., Swati Pawa, Richard S Kwon, Douglas S Fishman, Nirav C Thosani, Amandeep Shergill, Samir Grover, Mohammad Al-Haddad, Stuart K Amateau, James L Buxbaum, Audrey H Calderwood, Jean M Chalhoub, Nayantara Coelho-Prabhu, Madhav Desai, Sherif E Elhanafi, Nauzer Forbes, Larissa L Fujii-Lau, Divyanshoo R Kohli, Jorge D Machicado, Neil B Marya, Wenly Ruan, Sunil G Sheth, Andrew Storm, Nikhil R Thiruvengadam, Sachin Wani, and Bashar J Qumseya

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Differences in Nursing Dietary Intake by Preferred Chronotype and Chronotype Mismatch to Assigned Shift, Rebecca Penders, Rachel Faulkner, Teresa Rangel, Ross Bindler, Trisha Saul, Marian Wilson, and Lindsey Miller

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Long-term efficacy of high-frequency (10 kHz) spinal cord stimulation for the treatment of painful diabetic neuropathy: 24-Month results of a randomized controlled trial., Erika A Petersen, Thomas G Stauss, James A Scowcroft, Michael J Jaasma, Elizabeth S Brooks, Deborah R Edgar, Judith L White, Shawn M Sills, Kasra Amirdelfan, Maged N Guirguis, Jijun Xu, Cong Yu, Ali Nairizi, Denis G Patterson, Kostandinos C Tsoulfas, Michael J Creamer, Vincent Galan, Richard H Bundschu, Neel D Mehta, Dawood Sayed, Shivanand P Lad, David J DiBenedetto, Khalid A Sethi, Johnathan H Goree, Matthew T Bennett, Nathan J Harrison, Atef F Israel, Paul Chang, Paul W Wu, Charles E Argoff, Christian E Nasr, Rod S Taylor, David L Caraway, and Nagy A Mekhail

MtrA modulates Mycobacterium tuberculosis cell division in host microenvironments to mediate intrinsic resistance and drug tolerance., Eliza J R Peterson, Aaron N Brooks, David J Reiss, Amardeep Kaur, Julie Do, Min Pan, Wei-Ju Wu, Robert Morrison, Vivek Srinivas, Warren Carter, Mario L Arrieta-Ortiz, Rene A Ruiz, Apoorva Bhatt, and Nitin S Baliga

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Identifying Gaps in Interpretive Services to Improve Patient Care: A Root Cause Analysis, Christiane Phillips, Reed Ritterbusch, Ken Scott, and Jenny Wickens

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Effect of COVID-19 vaccination and booster on maternal-fetal outcomes: a retrospective cohort study., Samantha N Piekos, Yeon Mi Hwang, Ryan T Roper, Tanya K Sorensen, Nathan D Price, Leroy Hood, and Jennifer J Hadlock

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Reply to: Hypothetical model ignores many important pathophysiologic mechanisms in fibromyalgia., Ana Margarida Pinto, Rinie Geenen, Tor D Wager, Winfried Häuser, Eva Kosek, Jacob N Ablin, Kirstine Amris, Jaime Branco, Dan Buskila, João Castelhano, Miguel Castelo-Branco, Leslie J Crofford, Mary-Ann Fitzcharles, Marina López-Solà, Mariana Luís, Tiago Reis Marques, Philip J Mease, Filipe Palavra, Jamie L Rhudy, Lucina Q Uddin, Paula Castilho, Johannes W G Jacobs, and José A P da Silva

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Emotion regulation and the salience network: a hypothetical integrative model of fibromyalgia., Ana Margarida Pinto, Rinie Geenen, Tor D Wager, Mark A Lumley, Winfried Häuser, Eva Kosek, Jacob N Ablin, Kirstine Amris, Jaime Branco, Dan Buskila, João Castelhano, Miguel Castelo-Branco, Leslie J Crofford, Mary-Ann Fitzcharles, Marina López-Solà, Mariana Luís, Tiago Reis Marques, Philip J Mease, Filipe Palavra, Jamie L Rhudy, Lucina Q Uddin, Paula Castilho, Johannes W G Jacobs, and José A P da Silva

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Reply to 'Imbalance of threat and soothing systems in fibromyalgia: rephrasing an established mechanistic model?'., Ana Margarida Pinto, Rinie Geenen, Tor D Wager, Mark A Lumley, Winfried Häuser, Eva Kosek, Jacob N Ablin, Kirstine Amris, Jaime Branco, Dan Buskila, João Castelhano, Miguel Castelo-Branco, Leslie J Crofford, Mary-Ann Fitzcharles, Marina López-Solà, Mariana Luís, Tiago Reis Marques, Philip Mease, Filipe Palavra, Jamie L Rhudy, Lucina Q Uddin, Paula Castilho, Johannes W G Jacobs, and José A P da Silva

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Neurophysiological and psychosocial mechanisms of fibromyalgia: A comprehensive review and call for an integrative model., Ana Margarida Pinto, Mariana Luís, Rinie Geenen, Filipe Palavra, Mark A Lumley, Jacob N Ablin, Kirstine Amris, Jaime Branco, Dan Buskila, João Castelhano, Miguel Castelo-Branco, Leslie J Crofford, Mary-Ann Fitzcharles, Winfried Häuser, Eva Kosek, Philip J Mease, Tiago Reis Marques, Johannes W G Jacobs, Paula Castilho, and José A P da Silva

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A novel scoring system concept for de novo spinal infection treatment, the Spinal Infection Treatment Evaluation Score (SITE Score): a proof-of-concept study., Jonathan Pluemer, Yevgeniy Freyvert, Nathan Pratt, Jerry E Robinson, Jared A Cooke, Zachary L Tataryn, Clifford A Pierre, Periklis Godolias, Sven Frieler, Alexander von Glinski, Emre Yilmaz, Zeyad A Daher, Hamzah A Al-Awadi, Mitchell H Young, Rod J Oskouian, and Jens R Chapman

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Incidence of injury and illness among paediatric Team USA athletes competing in the 2020 Tokyo and 2022 Beijing Olympic and Paralympic Games., Eric G Post, Travis Anderson, Jeffrey S Shilt, Eric L Dugan, Stephanie C Clark, Emily G Larson, Kayle E Noble-Taylor, David M Robinson, Amber T Donaldson, Jonathan T Finnoff, and William M Adams

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What Can Ribo-Seq, Immunopeptidomics, and Proteomics Tell Us About the Noncanonical Proteome?, John R Prensner, Jennifer G Abelin, Leron W Kok, Karl R Clauser, Jonathan M Mudge, Jorge Ruiz-Orera, Michal Bassani-Sternberg, Robert L Moritz, Eric W Deutsch, and Sebastiaan van Heesch

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Toward structuring real-world data: Deep learning for extracting oncology information from clinical text with patient-level supervision., Sam Preston, Mu Wei, Rajesh Rao, Robert Tinn, Naoto Usuyama, Michael Lucas, Yu Gu, Roshanthi Weerasinghe, Soohee Lee, Brian D. Piening, Paul Tittel, Naveen Valluri, Tristan Naumann, Carlo Bifulco, and Hoifung Poon

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Cementless Metal-Free Ceramic-Coated Shoulder Resurfacing., James W. Pritchett

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Clinical outcomes and proximal junctional failure in adult spinal deformity patients corrected to normative alignment versus functional alignment., Themistocles S Protopsaltis, Fares Ani, Alexandra Soroceanu, Renaud Lafage, Han Jo Kim, Eaman Balouch, Zoe Norris, Justin S Smith, Alan H Daniels, Eric O Klineberg, Christopher P Ames, Robert Hart, Shay Bess, Christopher I Shaffrey, Frank J Schwab, Lawrence G Lenke, Virginie Lafage, and Munish C Gupta

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Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy, Cristina Puig-Saus, Barbara Sennino, Songming Peng, Clifford L Wang, Zheng Pan, Benjamin Yuen, Bhamini Purandare, Duo An, Boi B Quach, Diana Nguyen, Huiming Xia, Sameeha Jilani, Kevin Shao, Claire McHugh, John Greer, Phillip Peabody, Saparya Nayak, Jonathan Hoover, Sara Said, Kyle Jacoby, Olivier Dalmas, Susan P Foy, Andrew Conroy, Michael C Yi, Christine Shieh, William Lu, Katharine Heeringa, Yan Ma, Shahab Chizari, Melissa J Pilling, Marc Ting, Ramya Tunuguntla, Salemiz Sandoval, Robert Moot, Theresa Hunter, Sidi Zhao, Justin D Saco, Ivan Perez-Garcilazo, Egmidio Medina, Agustin Vega-Crespo, Ignacio Baselga-Carretero, Gabriel Abril-Rodriguez, Grace Cherry, Deborah J Wong, Jasreet Hundal, Bartosz Chmielowski, Daniel E Speiser, Michael T Bethune, Xiaoyan R Bao, Alena Gros, Obi L Griffith, Malachi Griffith, James R Heath, Alex Franzusoff, Stefanie J Mandl, and Antoni Ribas

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Role of a multidisciplinary pulmonary embolism response team and impact of interventional therapy in the management of patients with intermediate-high risk pulmonary embolism, Juan N Pulido, Robert Fletcher, Michelle A. Poitevin, Kristina Pratt, Paul P Huang, Eric J Lehr, and George P Pappas

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Outcomes of patients with intermediate risk pulmonary embolism treated with a multidisciplinary Pulmonary Embolism Response Team. The emergent role of percutaneous catheter thrombectomy and the importance of cardiac surgery engagement, Juan N Pulido, Robert Fletcher, Michelle A. Poitevin, Kristina Pratt, Paul P Huang, George P Pappas, and Eric J Lehr

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Noninvasive testing for advanced fibrosis in patients with diabetes with fatty liver disease needs further evaluation of cutoff values., Pankaj Rajvanshi and Srikrishna Gurumurthy

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A meta-analysis of rice phosphoproteomics data to understand variation in cell signalling across the rice pan-genome., Kerry A Ramsbottom, Ananth Prakash, Yasset Perez Riverol, Oscar Martin Camacho, Zhi Sun, Deepti J Kundu, Emily Bowler-Barnett, Maria Martin, Jun Fan, Dmytro Chebotarov, Kenneth L McNally, Eric W Deutsch, Juan Antonio Vizcaíno, and Andrew R Jones

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Exercise, diet, and sleep habits of nurses working full-time during the COVID-19 pandemic: An observational study., Teresa Rangel, Trisha Saul, Rom Leidner, J K Roney, Rebecca Penders, Rachel Faulkner, L Miller, Marietta Sperry, L James, and M L Wilson

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Biological BMI uncovers hidden health risks and is more responsive to lifestyle shifts, Noa Rappaport and Kengo Watanabe

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(543) Sex Differences in Clinical Presentation and Outcomes of Adults Hospitalized with COVID-19 Pneumonia After Administration of Infliximab, Abatacept or Cenicriviroc: Subgroup Analysis from the ACTIV-1 Master Protocol, Adriana Rauseo, Tatyana Der, Radica Alicic, Bindu Balani, Caryn Morse, Pearl Zakroysky, Linda Shaw, Jane Atkinson, and William G. Powderly

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Advanced artificial intelligence-guided hemodynamic management within cardiac enhanced recovery after surgery pathways: A multi-institution review., V Seenu Reddy, David M Stout, Robert Fletcher, Andrew Barksdale, Manesh Parikshak, Chanice Johns, and Marc Gerdisch

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Development of multidrug-resistant Mycobacterium tuberculosis in the biofilm of a peritoneal-venous shunt, Romany M Redman, Timothy D Maughan, Charles B Smith, Peter F Crossno, and Donald L Granger

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ProteomicsML: An Online Platform for Community-Curated Data sets and Tutorials for Machine Learning in Proteomics., Tobias G Rehfeldt, Ralf Gabriels, Robbin Bouwmeester, Siegfried Gessulat, Benjamin A Neely, Magnus Palmblad, Yasset Perez-Riverol, Tobias Schmidt, Juan Antonio Vizcaíno, and Eric W Deutsch